Results 151 to 160 of about 1,818,147 (330)

Lactate‐Activated GPR132‐Src Signal Induces Macrophage Senescence and Aggravates Atherosclerosis Under Diabetes

Advanced Science, EarlyView.
Elevated lactate in diabetes activates the GPR132‐Src pathway in macrophages, inducing macrophage senescence and further enhancing foam cell formation. This mechanism exacerbates atherosclerotic progression. Abstract Diabetes is widely acknowledged as a significant risk factor for atherosclerosis, facilitating plaque formation through various ...
Xiaofeng Ge, Shuying Wang, Zhaokai Li, Jing Yu, Binbin Liu, Ruiying Wang, Shichen Bu, Nawsher wan, Yan Wang, Cuilian Dai, Yijun Lin   +10 more
wiley   +1 more source

Use of Pressor Agents in Shock in Myocardial Infarction [PDF]

, 1958
O. Garai, Karen S. Smith
openalex   +1 more source

Delivery of Molecular Hydrogen for Precision Immunomodulation: Mechanisms, Detection Methods, and Applications

Advanced Science, EarlyView.
This review focuses on the immunomodulatory mechanisms of molecular hydrogen, the recent detection methods, and the classification advanced molecular hydrogen delivery materials. It provides a detailed description of their applications in areas such as arthritis, chronic wounds, cardiovascular injury, tumors, and bacterial infections, aiming to enhance
Gangfeng Li, Hannan Cui, Ruixiao Fan, Guming Liu, Zishuo Hou, Yibo Zhang, Xuanming Che, Tengjiao Wang, Hongbo Wei, Peng Li   +9 more
wiley   +1 more source

The Prevention of Thromboembolic Complications in Myocardial Infarction by Anticoagulant Therapy [PDF]

, 1956
Helen I. Glueck, Henry W. Ryder, P. Wasserman   +2 more
openalex   +1 more source

PFKM‐Driven Lactate Overproduction Promotes Atrial Fibrillation via Triggering Cardiac Fibroblasts Histone Lactylation

Advanced Science, EarlyView.
The upregulation of PFKM activates glycolysis, thereby enhancing lactate production in atrial tissue. Atrial lactate accumulation promotes global lactylation and H3K18 lactylation in atrial fibroblasts. P300‐mediated H3K18 lactylation up‐regulates TGF‐β1 transcription, leading to fibroblast activation and thereby contributing to atrial fibrosis.
Ning Fang, Ning Zhang, Xiaohui Jiang, Sen Yan, Zhiqi Wang, Qianhui Gao, Mingcheng Xu, Lin Mu, Xiaoming Li, Jiuling Chen, Song Zhang, Yu Duan, Fengxiang Yun, Luyifei Li, Yun Zhang, Yongtai Gong   +15 more
wiley   +1 more source

Real‐World Comparison of Ticagrelor and Clopidogrel: Rosetta Stone or Lost in Translation?

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Brian A. Bergmark
doaj   +1 more source

Thromboembolic Complications Following So-called "Good Risk" Cases of Myocardial Infarction [PDF]

, 1956
Adolfo Francisco, Irving S. Wright
openalex   +1 more source

Human cardiac organoids for the modelling of myocardial infarction and drug cardiotoxicity

Nature Biomedical Engineering, 2020
D. Richards, D. Richards, Yang Li, Charles M. Kerr, Jenny Yao, Jenny Yao, G. Beeson, Robert C. Coyle, Xun Chen, Jia Jia, B. Damon, Robert C. Wilson, E. Hazard, G. Hardiman, G. Hardiman, D. Menick, C. Beeson, Hai Yao, Tong Ye, Ying Mei, Ying Mei   +20 more
semanticscholar   +1 more source

Catalytic Hairpin Assembly‐Propelled Weak‐Inputs‐Strong‐Outputs (CP‐WISO) DNA Logic Nanodevices with Orthogonal Design and Contrary Logic Responses

Advanced Science, EarlyView.
Catalytic hairpin assembly‐propelled weak‐inputs‐strong‐outputs (CP‐WISO) DNA logic nanodevices with orthogonal design and contrary logic responses are innovatively fabricated. Moreover, the even and odd parity generators/checkers for ensuring normal molecular data transmission, and the logic‐programmed miRNA biosensors with ratiometric fluorescent ...
Xujuan Lv, Jiawen Han, Juan Wang, Zhihua Lv, Baojian Huang, Shuai Qin, Xuxin Yan, Shaojun Dong, Daoqing Fan   +8 more
wiley   +1 more source

Effects of Papaverine upon Ectopic Ventricular Tachycardia Produced by Myocardial Infarction [PDF]

, 1953
A. Sidney Harris, A Estandía, ABDO BISENI, Herbert T. Smith   +3 more
openalex   +1 more source