Results 161 to 170 of about 1,289,832 (353)

(Apo)Lipoprotein Profiling with Multi‐Omics Analysis Identified Medium‐HDL‐Targeting PSRC1 with Therapeutic Potential for Coronary Artery Disease

Advanced Science, EarlyView.
Lipid content in medium high‐density lipoprotein (HDL) particles, particularly cholesteryl esters, is identified as causally protective of atherosclerosis, and further ASCVD. Evidence from multi‐omics layers of data consistently supports PSRC1 with therapeutic potential for coronary artery disease (CAD), but not ischemic stroke.
Yingmei Li, Sihan Wang, Ling Liu, Hao Cai, Yacan Huang, Mingjing Gao, Xiaogang Zhang, Qingqing Wu, Gaokun Qiu   +8 more
wiley   +1 more source

Review of Atrioventricular Node Ablation Combined with Permanent His-Purkinje Conduction System Pacing in Patients with Atrial Fibrillation with Heart Failure

Reviews in Cardiovascular Medicine
With the advancement of pacing technologies, His-Purkinje conduction system pacing (HPCSP) has been increasingly recognized as superior to conventional right ventricular pacing (RVP) and biventricular pacing (BVP).
Lina Wang, Chen Tan, Jingshu Lei, CHONGYOU LEE   +3 more
doaj   +1 more source

LncRNA CAIF inhibits autophagy and attenuates myocardial infarction by blocking p53-mediated myocardin transcription

Nature Communications, 2018
Increasing evidence suggests that long noncoding RNAs (lncRNAs) play crucial roles in various biological processes. However, little is known about the effects of lncRNAs on autophagy.
Cuiyun Liu, Yuhui Zhang, Ruibei Li, Luyu Zhou, T. An, Rong-cheng Zhang, M. Zhai, Yan Huang, K. Yan, Yanhan Dong, M. Ponnusamy, Chan Shan, Sheng Xu, Qi Wang, Yan-hui Zhang, Jian Zhang, Kun Wang   +16 more
semanticscholar   +1 more source

KLF1 Promotes Cardiomyocyte Proliferation and Heart Regeneration Through Regulation of Wnt/β‐Catenin Signaling Pathway

Advanced Science, EarlyView.
In KLF1‐on (neonatal and Klf1 overexpression hearts) models, KLF1 regulates Wnt/β‐catenin signaling pathway and the expression of cell proliferation‐related genes via transcriptional and epigenetic mechanisms, which induces cardiomyocyte proliferation and cardiac regeneration in mice after myocardial infarction.
Yanglin Hao, Xi Zhang, Shuan Ran, Yuan Li, Weicong Ye, Song Wang, Xiaohan Li, Zilong Luo, Jiulu Zhao, Junjie Zong, Kexiao Zheng, Ran Li, Han Zhang, Longyong Lai, Pinyan Huang, Zifeng Zou, Wang Zhan, Zhang Yue, Jie Wu, Jiahong Xia   +19 more
wiley   +1 more source

Targeting miRNA‐1a and miRNA‐15b: A Novel Combinatorial Strategy to Drive Adult Cardiac Regeneration

Advanced Science, EarlyView.
The article explores a novel therapeutic strategy for cardiac regeneration by targeting miRNA‐1a and miRNA‐15b. Combinatorial inhibition of miR‐1a and miR‐15b enhances cardiomyocyte proliferation, improves heart function, and reduces fibrosis in myocardial infarction models.
Ting Yuan, Meiqian Wu, Chaonan Zhu, Hao Yu, Minh Duc Pham, Katharina Bottermann, Yijie Mao, Yue Wang, Mathias Langner, Mirko Peitzsch, Arka Provo Das, Silke Kauferstein, Jonathan Ward, Peter Mirtschink, Andreas Michael Zeiher, Stefanie Dimmeler, Jaya Krishnan   +16 more
wiley   +1 more source

Changes in the precordial electrocardiogram produced by extension of anteroseptal myocardial infarction [PDF]

, 1945
Francis F. Rosenbaum, Frank N. Wilson, Franklin D. Johnston   +2 more
openalex   +1 more source

MYOCARDIAL INFARCTION [PDF]

Heart, 1944
T E, Lowe, W B, Wartman
openaire   +4 more sources

Myocardial infarction [PDF]

Heart, 2002
M K, Davies, A, Hollman
openaire   +2 more sources

Neutrophils in Post-myocardial Infarction Inflammation: Damage vs. Resolution?

Frontiers in Cardiovascular Medicine, 2019
Inflammation not only plays a crucial role in acute ischemic cardiac injury, but also contributes to post-infarction repair and remodeling. Traditionally, neutrophils have been merely considered as detrimental in the setting of an acute myocardial ...
S. Puhl, S. Steffens
semanticscholar   +1 more source

MMP9High Neutrophils are Critical Mediators of Neutrophil Extracellular Traps Formation and Myocardial Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
During a heart attack, neutrophils rapidly activate and differentiate into a specific subset characterized by high levels of MMP9, a tissue‐damaging enzyme, via the SPI1/CST7 pathway. These neutrophils form harmful net‐like structures (Neutrophil extracellular traps, NETs) that exacerbate heart injury.
Shiyu Hu, Feng Zhang, Jingpu Wang, Jian Zhang, Chenguang Li, Yang Lyu, Yiwen Wang, Rong Huang, Yang Gao, Hongbo Yang, Juying Qian, Wenwen Tang, Jiatian Cao, Junbo Ge   +13 more
wiley   +1 more source