Results 41 to 50 of about 1,070,380 (336)

Understanding myocardial infarction [PDF]

open access: yesF1000Research, 2018
Over the last 40 years, our understanding of the pathogenesis of myocardial infarction has evolved and allowed new treatment strategies that have greatly improved survival. Over the years, there has been a radical shift in therapy from passive healing of the infarction through weeks of bed rest to early discharge usually within 2 to 3 days as a result ...
Moussa Saleh, John A Ambrose
openaire   +3 more sources

Dietary Capsaicin Improves Glucose Homeostasis and Alters the Gut Microbiota in Obese Diabetic ob/ob Mice

open access: yesFrontiers in Physiology, 2017
Background: The effects of capsaicin on obesity and glucose homeostasis are still controversial and the mechanisms underlying these effects remain largely unknown.
Jun-Xian Song   +23 more
doaj   +1 more source

The heartbreak of depression: 'Psycho-cardiac' coupling in myocardial infarction [PDF]

open access: yes, 2017
Ample evidence identifies strong links between major depressive disorder (MDD) and both risk of ischemic or coronary heart disease (CHD) and resultant morbidity and mortality. The molecular mechanistic bases of these linkages are poorly defined. Systemic
Budiono, Boris P   +5 more
core   +1 more source

Competing Risks of Cardiovascular Versus Noncardiovascular Death During Long‐Term Follow‐Up After Acute Coronary Syndromes

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundUnderstanding the relative risk of cardiovascular versus noncardiovascular death is important for designing clinical trials. These risks may differ depending on patient age, sex, and type of acute coronary syndrome (ACS).
Alexander C. Fanaroff   +9 more
doaj   +1 more source

Coronary CT Angiography and 5-Year Risk of Myocardial Infarction. [PDF]

open access: yes, 2018
BACKGROUND: Although coronary computed tomographic angiography (CTA) improves diagnostic certainty in the assessment of patients with stable chest pain, its effect on 5-year clinical outcomes is unknown.
Adamson, Philip D.   +37 more
core   +6 more sources

Determination of Nitric Oxide and Its Metabolites in Biological Tissues Using Ozone-Based Chemiluminescence Detection: A State-of-the-Art Review

open access: yesAntioxidants
Ozone-based chemiluminescence detection (CLD) has been widely applied for determining nitric oxide (•NO) and its derived species in many different fields, such as environmental monitoring and biomedical research.
Junjie Li   +3 more
doaj   +1 more source

Comparing routine administrative data with registry data for assessing quality of hospital care in patients with myocardial infarction using deterministic record linkage

open access: yesBMC Health Services Research, 2016
Background Assessment of quality of care in patients with myocardial infarction (MI) should be based on data that effectively enable determination of quality.
Birga Maier   +8 more
doaj   +1 more source

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

open access: yesFEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson   +7 more
wiley   +1 more source

An unusual myocardial infarction [PDF]

open access: yesEcho Research and Practice, 2014
SummaryWe present a 74-year-old male with a chondrosarcoma, who presented with chest pain. The history, electrocardiogram (ECG), and biomarkers established the diagnosis of myocardial infarction (MI); angiography did not show coronary atherosclerosis and, both initial transthoracic echocardiogram and chest computed tomography (CT), did not demonstrate ...
Domenico Galzerano   +3 more
openaire   +3 more sources

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