Results 131 to 140 of about 176,278 (292)
Short‐ and Long‐Term Outcomes of Open, Laparoscopic, and Robot‐Assisted Surgery for Rectal Cancer
Annals of Gastroenterological Surgery, EarlyView.Robot‐assisted rectal resection demonstrated superior short and long‐term outcomes compared to laparoscopic and open approaches. ABSTRACT Background Robot‐assisted surgery has short‐term benefits in rectal cancer surgery; however, its long‐term advantages remain unclear. This study compared short‐ and long‐term outcomes of open, laparoscopic, and robot‐
Marie Hanaoka +8 more
wiley +1 more source
Myocardial protection by insulin at reperfusion requires early administration and is mediated via Akt and p70s6 kinase cell-survival signaling [PDF]
, 2001 The "metabolic cocktail" comprising glucose-insulin-potassium administrated at reperfusion reduces infarct size in the in vivo rat heart. We propose that insulin is the major component mediating this protection and acts via Akt prosurvival signaling ...
Jonassen, A.K. +3 more
core
Cell Membrane‐Coated Lipid Nanoparticles for Drug Delivery
Aggregate, EarlyView.This review highlights recent progress in cell membrane‐coated lipid nanoparticles (CMC‐LNPs), focusing on their design, preparation methods, functional integration, and biomedical applications. It discusses various types of LNPs and coating strategies, characterization techniques, therapeutic functions, and applications.
Moataz B. Zewail +5 more
wiley +1 more source
The Expanding Clinical and Genetic Spectrum of Muscle Glycogen Storage Disease 0, (GSD0B)
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Glycogen storage disorders are a group of genetic disorders affecting glucose homeostasis in the body. Muscular glycogen stores are essential for liberating glucose for energy supply during bursts of activity and sustained muscle work. Muscle glycogen storage disease 0 (GSD0B) is associated with biallelic variants in GYS1 causing muscular ...
Sarah Donoghue +16 more
wiley +1 more source
Protective Action of Methylprednisolone on the Myocardium during Experimental Myocardial Ischemia in the Cat [PDF]
, 1974 James A. Spath +2 more
openalex +1 more source
Autophagy in myocardial ischemia and ischemia/reperfusion
Cardiovascular PathologyMyocardial infarction (MI) is a life-threatening condition that leads to loss of viable heart tissue. The best way to treat acute MI and limit the infarct size is to re-open the occluded coronary artery and restore the supply of oxygenated and nutrient-rich blood, but reperfusion can cause additional damage.
Aleksandra Aljakna Khan, Sara Sabatasso
openaire +3 more sources
m6A Methylation‐Induced Autophagy Impairment by TFEB Regulation in SOD1‐G93A ALS Cell Model
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT We investigate the role of m6A RNA methylation in regulating transcription factor EB (TFEB) and its contribution to mitochondrial autophagy (mitophagy) dysfunction in amyotrophic lateral sclerosis (ALS). ALS cell models were used to analyse mitophagy markers and TFEB expression under METTL3 and TFEB modulation, using RT‐qPCR, Western blot ...
Di An +7 more
wiley +1 more source
The Pathophysiology of Malignant Ventricular Arrhythmias During Acute Myocardial Ischemia [PDF]
, 1974 David O. Williams +4 more
openalex +1 more source
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.ABSTRACT Turner syndrome (TS) is frequently complicated by congenital heart disease (CHD). While left‐sided lesions such as bicuspid aortic valve (BAV) and coarctation of the aorta are the most common structural heart lesions in TS, other anomalies, such as aortic arch malformations, hypoplastic left heart syndrome (HLHS), persistent left superior vena
Katya de Groote +9 more
wiley +1 more source