Results 221 to 230 of about 217,798 (269)

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source

Metformin Attenuates Myocardial Ischemia-Reperfusion Injury in Rats by Modulating JNK Pathway and Inhibiting PANoptosis Mechanisms. [PDF]

Cardiovasc Ther
Hou B, Hou X, Zhang L, Liu T, Li Y, Dong R.   +5 more
europepmc   +1 more source

Incident heart failure: comparing management and outcome in primary and hospital settings in Western Sweden 2008–2017

ESC Heart Failure, Volume 12, Issue 2, Page 832-838, April 2025.
Abstract Aim Heart failure (HF) is a highly prevalent condition managed in both primary care (PC) and hospital care (HC)‐based settings. HF patients managed in these two settings may differ in their demography, comorbidities and outcomes, so we aimed to compare the patient management in PC and HC in the Västra Götaland Region (VGR) in Sweden.
Xiaojing Chen, Aldina Pivodic, Maria Schaufelberger, Annika Rosengren, Michael Fu   +4 more
wiley   +1 more source

Transthyretin amyloid cardiomyopathy: Literature review and red‐flag symptom clusters for each cardiology specialty

ESC Heart Failure, Volume 12, Issue 2, Page 955-967, April 2025.
Abstract Wild‐type transthyretin amyloid cardiomyopathy (ATTRwt‐CM) is a progressive and infiltrative cardiac disorder that may cause fatal consequences if left untreated. The estimated survival time from diagnosis is approximately 3–6 years. Because of the non‐specificity of initial symptom manifestation and insufficient awareness among treating ...
Yasuhiro Izumiya, Toru Kubo, Jin Endo, Seiji Takashio, Masatoshi Minamisawa, Jun Hamada, Tomonori Ishii, Hajime Abe, Hiroaki Konishi, Kenichi Tsujita   +9 more
wiley   +1 more source

Inhibition of TREM1 attenuates myocardial ischemia-reperfusion injury-induced cardiomyocyte pyroptosis by suppressing the activation of the NF-κB signaling pathway. [PDF]

PLoS One
Xu X, Cai L, Dang X, Han J, Kou Y, Rong C, Kou J.   +6 more
europepmc   +1 more source

Clinical Efficacy of Periosteum‐Preserving Iliac Crest Transverse Transport for Symptomatic High‐Level Lower Extremity Arteriosclerosis Obliterans

Chronic Diseases and Translational Medicine, EarlyView.
Guangchen Nie, Xiangyue Meng, Yong Liu, Xuguang Hao, Yang Liu, Shouyang Xiang, Yongxin Huo, Long Jiang, Qiang Xu, Yicun Lu   +9 more
wiley   +1 more source

Meta‐analysis of sotagliflozin, a dual sodium‐glucose‐cotransporter 1/2 inhibitor, for heart failure in type 2 diabetes

ESC Heart Failure, Volume 12, Issue 2, Page 968-979, April 2025.
Abstract Sodium‐glucose co‐transporters (SGLTs) mediate sodium and glucose transport across cell membranes. SGLT2 inhibitors have a recognized place within heart failure (HF) guidelines. We evaluated the effect of sotagliflozin on HF and cardiovascular outcomes in participants with type 2 diabetes. Scopus, Medline, Embase and Central were searched from
Maria Anna Bantounou, Panagiotis Sardellis, Josip Plascevic, Ribeya Awaes‐Mahmood, Justyna Kaczmarek, Daniel Black Boada, Rosa Thuemmler, Sam Philip   +7 more
wiley   +1 more source

Pathologically responsive ZnSrMo-LDH/Cu nanozymes with cascade antioxidant and angiogenic functions for myocardial ischemia-reperfusion treatment. [PDF]

Theranostics
Xu J, Zhang S, Yang Y, Wei X, Fang Y, Wang Z, Lan L, Shen J, Liu E, Hu W, Hu T, Yu C, Liang R, Lyu L.   +13 more
europepmc   +1 more source

Reviewer #2 (Public Review): Resident and recruited macrophages differentially contribute to cardiac healing after myocardial ischemia

Tobias Weinberger, Denise Messerer, Markus Joppich, Maximilian Fischer, Clarisabel Garcia, Konda Kumaraswami, Vanessa Wimmler, Sonja Ablinger, Saskia Räuber, Jiahui Fang, Lulu Liu, Wing Han Liu, Julia Winterhalter, Johannes Lichti, Lukas Tomas, Dena Esfandyari, Guelce Percin, Sandra Martin Salamanca, Andrés Hidalgo, Claudia Waskow, Stefan Engelhardt, Andrei Todica, Ralf Zimmer, Clare Pridans, Elisa Gomez Perdiguero, Christian Schulz   +25 more
openalex   +1 more source

Si-Miao-Yong-An decoction suppresses necroptosis by regulating the p53 pathway in myocardial ischemia/reperfusion injury. [PDF]

Sci Rep
Li X, Bai L, Ye M, Liu W, Lin Q, Ning X, Chen X, Ji F.   +7 more
europepmc   +1 more source