Results 151 to 160 of about 190,574 (306)

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

Evaluation of the Effect of Myocardial Localisation Errors on Myocardial Blood Flow Estimates from Myocardial Perfusion MRI [PDF]

, 2010
Biglands, J, Boyle, RD, Jerosch-Herold, M, Larghat, A, Magee, D, Plein, S, Radjenovic, A   +6 more
core   +1 more source

Incidence, contributing factors, and predictors of diagnostic errors in medical inpatients: A retrospective cohort study

Journal of Hospital Medicine, EarlyView.
Abstract Background Diagnostic error is a major patient safety concern in hospitals, yet most studies have focused on selected high‐risk subgroups, leaving the broader general internal medicine inpatient population understudied. Objectives To determine the incidence, contributing factors, resulting harm, and predictors of diagnostic error in medical ...
Caterina E. Marx, Elena Hofmann, Martin Perrig, Gurpreet Dhaliwal, Wolf Hautz, Jörg P. Isenegger, Ernst Lipp, Drahomir Aujesky, Manuel R. Blum, Tobias Tritschler   +9 more
wiley   +1 more source

Early prediction of multiple organ failure for sepsis patients based on machine learning algorithms

Journal of Intelligent Medicine, EarlyView.
Abstract In recent years, there has been a notable rise in sepsis incidence leading to more multiple organ failure and higher mortality. The lack of effective treatments for sepsis highlights the importance of early prediction in preventing multiple organ failure. This study aimed to develop a model for the early prediction of multiple organ failure in
Runnan He, Nan Su, Yuqing Wang, Yulin Sun, Xin Weng, Tania Pereira, Chenggong Hu, Keliang Xie, Meijun Pang, Kuo Zhang, Chuanxiang Huang, Xiuyun Liu   +11 more
wiley   +1 more source

Towards Clinical Translation of Intravoxel Incoherent Motion MRI: Acquisition and Analysis Consensus Recommendations

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Intravoxel incoherent motion (IVIM) MRI allows for simultaneous assessment of tissue microcirculation (perfusion) and diffusion of water. In single‐center studies, IVIM has shown great potential for diagnosis, treatment outcome prediction, and treatment monitoring for many different diseases and organs.
Eric E. Sigmund, Susanne S. Rauh, Mami Iima, Christian Federau, Diego Hernando, Oscar Jalnefjord, Jacobus F. A. Jansen, Jonas Jasse, Neil Peter Jerome, Misha P. T. Kaandorp, Sila Kurugol, Frederik B. Laun, Mira M. Liu, Alexandra Ljimani, Thoralf Niendorf, David A. Reiter, Mohammed Salman Shazeeb, Amita Shukla‐Dave, Julia Stabinska, Andreas Wetscherek, Peter T. While, Dan Wu, Denis Le Bihan, Oliver J. Gurney‐Champion   +23 more
wiley   +1 more source

Incidental Detection of Inadvertent Pacing Lead Placement in the Left Ventricle by Myocardial Perfusion Imaging Study [PDF]

, 2020
Tung, Robert
core   +2 more sources

Tranexamic Acid in Lower Extremity Endoprosthetic Reconstruction for Oncologic Indications: A Retrospective Comparative Study of 617 Patients

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives While tranexamic acid (TXA) reduces blood loss in orthopedic surgery, thromboembolic concerns in cancer patients have limited adoption in orthopedic oncology. This study evaluated TXA efficacy and safety in patients undergoing endoprosthetic reconstruction for oncologic indications.
Stephen W. Chenard, Akhil Rekulapelli, Riley S. Gilbertson, Connor S. Charton, William F. Hefley, Michael J. Colello, Jennifer L. Halpern, Herbert S. Schwartz, Daniel J. Johnson, Jonathan G. Schoenecker, Joshua M. Lawrenz   +10 more
wiley   +1 more source

Deubiquitinase USP7 Regulates Neutrophil Extracellular Trap Formation and Inflammation in Lipopolysaccharide‐Treated Mice Through ICAM‐1 Expression

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Sepsis is typified by organ failure due to an unchecked host reaction to infection. This study aims to explore the mechanism of ubiquitin‐specific peptidase 7 (USP7) in sepsis with the involvement of intercellular adhesion molecule‐1 (ICAM‐1).
Hui Xu, Qi Wang, Jing‐Xian Fan, Yong‐Fu Xu, Jiao Yu   +4 more
wiley   +1 more source

Triglyceride‐Glucose Index‐Based Nomogram for Predicting Short‐Term Mortality in Sepsis Patients

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The triglyceride‐glucose (TyG) index, a marker of insulin resistance, is associated with outcomes in critical illness; however, its predictive role for 28‐day mortality in Asian patients with sepsis has not been established. To address this, the current investigation was designed to evaluate its prognostic significance and to construct a risk ...
Jing Zhang, Yu‐Jing Jiang, Ya‐Ting Lv, Tong‐Qin Li, Li Ma   +4 more
wiley   +1 more source

Protective Effects of Riociguat Against Contrast‐Induced Nephropathy: An Experimental and Machine Learning‐Based Study in Rats

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Contrast‐induced nephropathy (CIN) is an important cause of acute kidney injury following exposure to iodinated contrast media, and effective preventive strategies remain limited. This study investigated the renoprotective effects of riociguat, a soluble guanylate cyclase stimulator, in an experimental rat model of CIN and explored machine ...
Mustafa Begenc Tascanov, Kenan Toprak, Sibel Turedi, İsmail Koyuncu, Zulkif Tanrıverdi, Necip Fazıl Dedeoglu, Halil Fedai, Asuman Bicer, İbrahim Halil Altıparmak, Recep Demirbag, Gencay Sarıısık   +10 more
wiley   +1 more source