Results 211 to 220 of about 554,014 (305)

Apigenin Protects Hypertensive Intracerebral Hemorrhage by Regulating Trx1 Through Binding to PRDX2

Phytotherapy Research, EarlyView.
ABSTRACT Intracerebral hemorrhage (ICH) remains the most severe stroke subtype with high mortality and disability rates. Although apigenin has shown cerebroprotective potential in preclinical studies, its mechanism of action, particularly in hypertensive ICH, remains poorly understood.
Hao‐chen Xu, Ming Liu, Ying‐ying Sun, Jie‐Dan Ping, Qing‐hua Cui, Jing‐zhou Chen, Hao Li   +6 more
wiley   +1 more source

Protosappanin A Alleviates Atherosclerosis by Regulating the MDM2/GPX4 Axis‐Mediated Endothelial Ferroptosis

Phytotherapy Research, EarlyView.
PTA alleviates atherosclerosis by regulating the MDM2/GPX4 axis‐mediated endothelial ferroptosis. ABSTRACT Endothelial ferroptosis is a crucial pathogenic driver of atherosclerosis (AS) progression. Protosappanin A (PTA), a bioactive compound from Caesalpinia sappan L., protects cardiovascular vessels by regulating ferroptosis.
Jiamei Fu, Lin Zhu, Wenwei Yang, Mengnan Li, Zhixin Wu, Shude Sun, Yabin Zhou   +6 more
wiley   +1 more source

Creation of a Standardized Myocardial Perfusion Single-photon Emission Computed Tomography Database to Enhance Coronary Artery Disease Research. [PDF]

J Med Signals Sens
Rahimian A, Moslehi M, Rabbani H, Etehadtavakol M, Dehghani T.   +4 more
europepmc   +1 more source

Endocytosis‐independent cytosolic entry of messenger RNA via fluorous bilayer zippering attenuating Toll‐like receptor signaling and enables ischemic tissue salvage

Smart Molecules, EarlyView.
The present study establishes a paradigm shift in synthetic mRNA delivery through the convergence of three orthogonal chemistries—perfluoro‐acylation, bio‐orthogonal click cross‐linking, and disulfide reduction—within a single, modular polymer architecture. Abstract A fundamental constraint of conventional messenger RNA (mRNA) delivery systems is their
Yue Wang, Haitao Xie, Guoqing Xiang, Yanhua Li, Changgui Tong, Hongyan Cui, Qixian Chen, Haidong Li, Yan Zhao   +8 more
wiley   +1 more source

Assessing Coronary Calcium Thresholds on Attenuation-Correction CT With Myocardial Perfusion Imaging Equating to Secondary Prevention. [PDF]

JACC Adv
Kyriakoulis I, Csecs I, Ahmed AI, Wright CX, Shanbhag A, Lemley M, Slomka P, Sinusas AJ, Miller EJ, Kokkinidis DG, Feher A.   +10 more
europepmc   +1 more source

Abnormal myocardial perfusion reserve and myocardial infarction determine cardiovascular outcomes in type 2 diabetes mellitus. [PDF]

Eur Heart J Cardiovasc Imaging
Sharrack N, Knott KD, Yeo JL, Kotecha T, Brown LAE, Porcari A, Adam RD, Gulsin GS, Thirunavukarasu S, Chowdhary A, Takafuji M, Levelt E, Greenwood JP, Buckley DL, Munyombwe T, Gale CP, Kellman P, Moon JC, Fontana M, McCann GP, Swoboda PP, Plein S.   +21 more
europepmc   +1 more source

Hemodynamic Effects of Prolonged Apneic Oxygenation in Laryngologic Surgery: A Randomized Controlled Pilot Trial

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Limited data exist on cardiocirculatory responses associated with extended periods of apnea during administration of high‐flow nasal oxygen for laryngologic surgery (apneic oxygenation with HFNO, AO‐HFNO). The possibility of hemodynamic compromise in the settings of acute hypercapnia, respiratory acidosis, hyperoxia, and IV ...
Vladimir Nekhendzy, Hendrikus J. Lemmens, Amit R. Saxena, Brita M. Mittal, Edward J. Damrose, C. Kwang Sung, Raffick Bowen   +6 more
wiley   +1 more source

Aspirin therapy after heart transplantation is associated with higher myocardial perfusion reserve assessed by cardiovascular magnetic resonance imaging. [PDF]

JHLT Open
Jablonowski R, Löfman IH, Andersson HB, Gjesdal G, Fogarasi C, Kellman P, Melin M, Engblom H, Arheden H, Carlsson M, Nickander J, Braun OÖ.   +11 more
europepmc   +1 more source

Correlation Between Anastomotic Leakage and the Anastomotic Position of the Gastric Conduit After Esophagectomy Using ICG Fluorescence Imaging Stratification

World Journal of Surgery, EarlyView.
This study aimed to clarify the correlation between anastomotic leakage and anastomotic position after esophagectomy for esophageal cancer, stratified by gastric conduit blood flow assessed using indocyanine green (ICG) fluorescence imaging. ABSTRACT Background This study aimed to clarify the correlation between anastomotic leakage and anastomotic ...
Yamato Ninomiya, Kazuo Koyanagi, Rie Nakashima, Kohei Tajima, Kohei Kanamori, Mika Ogimi, Yoshiaki Shoji, Akihito Kazuno, Miho Yamamoto, Masaki Mori   +9 more
wiley   +1 more source

Utility of stress parameters to determine prognosis following normal exercise SPECT myocardial perfusion imaging. [PDF]

Int J Cardiovasc Imaging
Shirazi Z, Adinehpour Z, Small TD, Wells RG, Boczar KE, Chow BJW, Small GR.   +6 more
europepmc   +1 more source