Results 251 to 260 of about 554,014 (305)

Inhibition of late sodium current prevents pathological hyperactivation of calcium/calmodulin‐dependent protein kinase IIδ in a murine model of acute doxorubicin‐related cardiotoxicity

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Doxorubicin (DOX) is a highly effective anthracycline, whose clinical application for cancer is limited by cardiotoxicity. The mechanisms underlying doxorubicin‐induced toxic cardiomyopathy (DICM) involve electrophysiological remodelling with intracellular Na+ overload because of increased late INa and hyperactivation of
Anna‐Lena Feder, Anna‐Maria Pfützenreuter, Lea Maria Funke, Maria Johanna Baier, Daniel Tarnowski, Laura Stengel, Lars Siegfried Maier, Can Martin Sag   +7 more
wiley   +1 more source

Heart failure medication to prevent cancer therapy–related cardiac dysfunction: A narrative review

British Journal of Pharmacology, EarlyView.
Advances in oncological therapies have improved cancer survival but also have increased the clinical incidence of cancer therapy–related cardiac dysfunction (CTRCD), a spectrum of conditions ranging from subclinical biomarker or strain abnormalities to progressive heart failure and cardiogenic shock.
Fabian Voß, Paul Goerke, Malte Kelm, Amin Polzin   +3 more
wiley   +1 more source

Myocardial perfusion improvement of saphenous vein Y-composite versus aortocoronary grafts during the first year after surgery. [PDF]

JTCVS Open
Sohn SH, Kang Y, Paeng JC, Hwang HY.
europepmc   +1 more source

Signal detection and characterisation of a novel drug–drug interaction between methadone and a synthetic cannabinoid receptor agonist

British Journal of Pharmacology, EarlyView.
Background and Purpose Little is known about how synthetic cannabinoid receptor agonist (SCRA) co‐use with other psychoactive substances may exacerbate risk of death. This study aimed to characterise the polypharmacy of deaths where SCRAs were detected at post‐mortem, investigate the cardiotoxicity of SCRAs and probe their inhibition of human ether‐a ...
Kirsten L. Rock, Louise M. Hesketh, Hongwei Cheng, Shuoqi Chen, Simon Hudson, Graeme Henderson, Jules C. Hancox, Michael J. Shattock, Michael J. Curtis, Caroline S. Copeland   +9 more
wiley   +1 more source

Flipping the Script: Pharmacologic Myocardial Perfusion Imaging and Percutaneous Coronary Intervention in a Patient With Dextrocardia and Situs Inversus Totalis. [PDF]

Cureus
Lacourt Sosa GL, Cota Ley R, Huertas Gomez Y, Rivera-Berrios R.   +3 more
europepmc   +1 more source

Multicenter Evaluation of Myocardial Flow Reserve as a Prognostic Marker for Mortality in ¹³N-Ammonia PET Myocardial Perfusion Imaging. [PDF]

Circ Cardiovasc Imaging
Ramirez G, Builoff V, Miller RJH, Lemley M, Carvajal-Juarez I, Alexanderson E, Rosamond TL, Song N, Travin MI, Slipczuk L, Einstein AJ, Wopperer SB, Di Carli MF, Chareonthaitawee P, Slomka PJ.   +14 more
europepmc   +1 more source

Impact of myocardial perfusion abnormalities on clinical outcomes in patients treated with percutaneous coronary intervention for chronic total occlusions. [PDF]

Eur Heart J Imaging Methods Pract
Henningsen JB, Søndergaard MM, Jørgensen SH, Søby JH, Böttcher M, Rasmussen LD, Christiansen EH, Holck EN, Jensen LO, Veien KT, Bouchelouche K, Pedersen CT, Kragholm KH, Eftekhari A.   +13 more
europepmc   +1 more source

Adenosine stress myocardial perfusion imaging and myocardial work in evaluating INOCA. [PDF]

Sci Rep
Zhang X, Dou S, Zhang F, Lou P, Jin J, Zhao Y, Zhao X, Li F, Li Y.   +8 more
europepmc   +1 more source

Coronary Artery Disease and Axillary Lymphadenopathy Post COVID-19 Vaccine Administration: Insights from Tl-201 Myocardial Perfusion Imaging. [PDF]

In Vivo
Chen TY, Tseng TC, Shen DH, Shiue YL, Yang JH, Chan HP.   +5 more
europepmc   +1 more source

Sotagliflozin Enhances Left Ventricular Function and Myocardial Perfusion in Chronic Myocardial Ischemia Through Metabolic and Redox Remodeling. [PDF]

Arterioscler Thromb Vasc Biol
Muir KC, Stone C, Reddy R, Kanuparthy M, Hamze J, Harris DD, Abid MR, Sellke FW.   +7 more
europepmc   +1 more source