Results 101 to 110 of about 108,555 (300)

Multiresolution spatiotemporal mechanical model of the heart as a prior to constrain the solution for 4D models of the heart. [PDF]

open access: yes, 2019
In several nuclear cardiac imaging applications (SPECT and PET), images are formed by reconstructing tomographic data using an iterative reconstruction algorithm with corrections for physical factors involved in the imaging detection process and with ...
Gullberg, Grant T   +6 more
core   +2 more sources

Stress Myocardial Perfusion Imaging— The Beginning…

open access: yesJACC: Cardiovascular Imaging, 2008
“There are no problems—only opportunities to be creative.”Dorye Roettger ([1][1]) Myocardial perfusion imaging was developed to meet the need to noninvasively detect the presence and extent of coronary disease.
openaire   +3 more sources

Loss of Hepatic Angiotensinogen Attenuates Diastolic Dysfunction in Heart Failure with Preserved Ejection Fraction

open access: yesAdvanced Science, EarlyView.
Increased hepatic angiotensinogen (AGT) abundance leads to cardiac diastolic dysfunction via the AngII‐independent pathway. Liver‐derived AGT is internalized by LRP2 in cardiac endothelial cells, subsequently contributing to myocardial diastolic dysfunction by suppressing microvascular angiogenesis via inhibiting the GATA2/Pim3 pathway.
Zetao Heng   +7 more
wiley   +1 more source

CD11b+CD43hiLy6Clo splenocyte‐derived macrophages exacerbate liver fibrosis via spleen–liver axis

open access: yesHepatology, EarlyView., 2022
A population of splenic monocytes migrate into the liver and shift to macrophages, which account for the exacerbation of liver fibrosis. Abstract Background and Aims Monocyte‐derived macrophages (MoMFs), a dominant population of hepatic macrophages under inflammation, play a crucial role in liver fibrosis progression.
Shaoying Zhang   +18 more
wiley   +1 more source

The relative contributions of myocardial perfusion, blood volume and extracellular volume to native T1 and native T2 at rest and during adenosine stress in normal physiology

open access: yesJournal of Cardiovascular Magnetic Resonance, 2019
Background Both ischemic and non-ischemic heart disease can cause disturbances in the myocardial blood volume (MBV), myocardial perfusion and the myocardial extracellular volume fraction (ECV). Recent studies suggest that native myocardial T1 mapping can
Jannike Nickander   +6 more
doaj   +1 more source

Noninvasive stress testing of myocardial perfusion defects: head-to-head comparison of thallium-201 SPECT to MRI perfusion [PDF]

open access: yes, 2018
Background: To evaluate the diagnostic value of magnetic resonance imaging (MRI) of myocardial perfusion in the assessment of flow-limiting epicardial stenosis in a head-to-head comparison with abnormal thallium-201 (201TI) single photon emission ...
Ambrosio, Giuseppe   +8 more
core  

Prognostic implications of myocardial perfusion imaging and coronary calcium score in a Macedonian cohort of asymptomatic patients with type 2 diabetes [PDF]

open access: yes, 2017
Aim: Type 2 diabetes is a risk factor for coronary artery disease; however, a number of studies have shown that patients are asymptomatic for coronary artery disease.
Apostolopoulos, Vasso   +5 more
core   +1 more source

Microglia Drive Peripapillary Vascular Density Reduction in Normal Tension Glaucoma by Regulating the Rpl17/Stat5b/Apoa1 Axis

open access: yesAdvanced Science, EarlyView.
This study revealed that E50K mutant microglia drive retinal peripapillary vascular density reduction in NTG via the Rpl17/Stat5b/Apoa1 axis and identified Apoa1 as a novel suppressor of retinal vascular endothelial cells. These findings identify a potential therapeutic target for glaucoma and support the clinical potential of EA for protecting RGCs ...
Di Zhang   +9 more
wiley   +1 more source

MYOCARDIAL PERFUSION IMAGING [PDF]

open access: yesThe Lancet, 1977
SimonP. Joseph   +3 more
openaire   +3 more sources

Targeting Histamine H4 Receptor in the Rostral Ventromedial Medulla to Relieve Hypertension

open access: yesAdvanced Science, EarlyView.
H4R and its downstream TRPV1 channel mediate the excitatory effect of TMN histaminergic afferent inputs on GABAergic sympathoinhibitory neurons in RVMM. Intranasal delivery of selective H4R agonist VUF 8430 suppresses renal sympathetic outflow and elicits sustained depressor and bradycardia responses in SHRs and CUMS‐induced hypertensive rats ...
Ying Shi   +18 more
wiley   +1 more source

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