Results 71 to 80 of about 104,281 (302)

Prevalence of myocardial viability assessed by single photon emission computed tomography in patients with chronic ischaemic left ventricular dysfunction [PDF]

, 2002
OBJECTIVE: To assess the prevalence of myocardial viability by technetium-99m (Tc-99m)-tetrofosmin/fluorine-18-fluorodeoxyglucose (FDG) single photon emission computed tomography (SPECT) in patients with ischaemic cardiomyopathy. DESIGN:
Bax, J.J. (Jeroen), Boersma, H. (Eric), Elhendy, A. (Abdou), Poldermans, D. (Don), Roelandt, J.R.T.C. (Jos), Schinkel, A.F.L. (Arend), Sozzi, F. (Fabiola), Valkema, R. (Roelf)   +7 more
core   +1 more source

A Soft Robotic Model for Simulating Heart Valve Disease and Cardiac Interventions

Advanced Science, EarlyView.
This paper introduces a fully synthetic fabrication methodology for a soft robotic, in‐vitro model of the left‐heart, complete with a functioning mitral valve apparatus. With a view towards patient‐specific modeling, we demonstrate physiological flow and pressure waveforms, tunable mitral valve function with clinical imaging compatibility, and its use ...
James Davies, Emanuele Nicotra, Kefan Zhu, Chi Cong Nguyen, Bibhu Sharma, Adrienne Ji, Phuoc Thien Phan, Jingjing Wan, Patrick Pruscino, Hermione Truong, Jelena Rnjak‐Kovacina, Hoang‐Phuong Phan, Christopher Hayward, Nigel Hamilton Lovell, Thanh Nho Do   +14 more
wiley   +1 more source

The Value of Cardiovascular Magnetic Resonance Myocardial Perfusion Imaging Combined with CT Fractional Flow Reserve in Predicting Cardiovascular Adverse Events in Obstructive Coronary Heart Disease

Guoji laonian yixue zazhi
Objective To analyze the predictive value of cardiovascular magnetic resonance (CMR) myocardial perfusion imaging combined with CT fractional flow reserve(CT-FFR) parameters in predicting cardiovascular adverse events in obstructive coronary heart ...
Jianchang Zhou, Liping Ji, Zhihong Meng, Fan Zhang, Yujia Cao, Wenhui Li   +5 more
doaj   +1 more source

Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis

Advanced Science, EarlyView.
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu, Yaqian Cui, Yongqiang Zhou, Yihui Zheng, Lijiang Huang, Leiming Jin, Qianhui Zhang, Pan Chen, Mengsha Lin, Jiaxi Ye, Yongqiang Xiong, Joo Young Huh, Xiang Hu, Xiaokun Li, Wu Luo, Guang Liang   +15 more
wiley   +1 more source

Unraveling septal perfusion abnormalities in Ebstein's anomaly: A case report contrasting PET MPI with myocardial reality

Radiology Case Reports
In Ebstein's anomaly, septal perfusion abnormality poses a challenge in traditional interpretations of myocardial blood flow. We report a single case of a 43‐year‐old female with known Ebstein’s anomaly who was referred for preoperative cardiac ...
Haluk Alibazoglu, MD, Adam M Khalil, Deniz Alibazoglu, Ahmed Sherif, MD, Ahmed Bafadel, MD, Amany Hillis, MD, Hidayath A Ansari, MD, Hani Sabbour, MD, Buket Alibazoglu, MD, Rawan A Hussein, CNMT, Mohammed E Khalil, MD   +10 more
doaj   +1 more source

Microvascular dysfunction in the immediate aftermath of chronic total coronary occlusion recanalization [PDF]

, 2016
Objectives The aim of this study was to compare microvascular resistance under both baseline and hyperemic conditions immediately after percutaneous coronary intervention (PCI) of a chronic total occlusion (CTO) with an unobstructed reference vessel in ...
Alamgir, Farquad, Cunnington, Michael S., Hoye, Angela, Ladwiniec, Andrew, Rossington, Jennifer, Thackray, Simon   +5 more
core   +2 more sources

Bench‐to‐Bedside Translation of Self‐Healing Colloidal Hydrogels as Next Generation Design of Flowable Hemostatic Matrix: From Preclinical Evaluation to Human Clinical Trials

Advanced Science, EarlyView.
ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng, Kaiwen Chen, Qiwei Ying, Shuya Wang, Xin Li, Guanlin Li, Yantao Zhao, Binghua Ma, Huanan Wang, Dawei Li, Lijun Zhang, Jian Zhang, Yu Zhao, Changle Ren, Baodong Chen, Yueming Song   +15 more
wiley   +1 more source

Perfusion Computed Tomography for the Assessment of Myocardial Viability — a Case Series

Journal of Interdisciplinary Medicine, 2016
Myocardial viability plays an important role in preventing the development of left ventricular remodeling following an acute myocardial infarction. A preserved viability in the infarcted area has been demonstrated to be associated with a lower amplitude ...
Morariu Mirabela, Opincariu Diana, Stănescu Alexandra   +2 more
doaj   +1 more source

Role of Tc-99m sestamibi SPECT/CT myocardial perfusion imaging in management of spontaneous coronary artery dissection: A case report

IHJ Cardiovascular Case Reports, 2018
Spontaneous coronary artery dissection (SCAD) is a rare sporadic disorder of abrupt dissection in the coronary arteries resulting in impaired perfusion to the myocardium. The authors present two cases of SCAD where myocardial perfusion imaging (MPI) done
Shelvin Kumar Vadi, Deepa Singh, Ashwani Sood, Ajay Bahl, Madan Parmar, Bhagwant Rai Mittal   +5 more
doaj   +1 more source

Mechanically Robust Biodegradable Stents With Theragenerative Vascular Responses via Combined 3D Printing and Janus Nanoengineering

Advanced Science, EarlyView.
This work introduces a theragenerative 3D‐printed biodegradable stent with Janus nanoarchitecture for spatially controlled vascular healing. A luminal tantalum ion–implanted surface accelerates endothelialization and hemocompatibility, while an abluminal sirolimus/poly‐L‐lactic acid–tantalum layer provides sustained drug release and suppresses smooth ...
Jong Hwa Seo, Dong‐Sung Won, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Chan Ho Moon, Ji Won Kim, Yubeen Park, Minho Kang, Dong Yun Lee, Donghyun Lim, Kisuk Yang, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Seokbeom Kim, Jun‐Kyu Park, Jung‐Hoon Park, Hyun‐Do Jung   +19 more
wiley   +1 more source