Results 291 to 300 of about 3,082,827 (354)

Myocardial protection and cardioplegia

Current Opinion in Cardiology, 1993
Over the past year there has been a tremendous enthusiasm for the novel technique of warm heart surgery. In contradistinction to hypothermic myocardial preservation, warm cardiac surgery provides for operative repair in a nonischemic heart. Warm cardioplegia can be administered in an antegrade or retrograde manner, continuously, and perhaps even ...
I B, Krukenkamp, S, Levitsky
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Myocardial Protection with Carvedilol

Journal of Cardiovascular Pharmacology, 1992
Carvedilol is a multiple-action cardiovascular agent that is both a beta-adrenoceptor antagonist and a vasodilator and has recently been made available for the treatment of mild-to-moderate hypertension. Clinical trials are ongoing to establish the efficacy of carvedilol in angina and congestive heart failure. beta-Adrenoceptor antagonists are known to
G Z, Feuerstein, S A, Hamburger, E F, Smith, A, Bril, R R, Ruffolo   +4 more
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Drugs mediating myocardial protection

European Journal of Anaesthesiology, 2009
The occurrence of myocardial ischaemia will result in either reversible or irreversible myocardial dysfunction. Even when revascularization is successful, some reperfusion injury may occur that transiently impairs myocardial function. Therefore, treatment should not only be directed towards prompt restoration of myocardial blood flow but measures ...
Stefan G, De Hert, Benedikt, Preckel, Markus W, Hollmann, Wolfgang S, Schlack   +3 more
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Myocardial protection for transplantation

Transplantation Proceedings, 1999
PROGRESS in the development of new techniques in surgery of heart transplantation had considerable influence on the creation of new methods for heart preservation. Currently, various cardioplegic solutions, developed for cardiac surgery, provide safe preservation of myocardial function for 5 to 6 hours, but remain unsatisfactory.
M, Garlicki, J, Kołcz, P, Rudziński, B, Kapelak, J, Sadowski, S, Wójcik, E, Pietrzyk, W, Frasik, J, Drukała, A, Dziatkowiak   +9 more
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Adenosine and myocardial protection

Journal of Cardiothoracic and Vascular Anesthesia, 1993
A DENOSINE (ADO, MW = 267.24) is an endogenous nucleoside (Fig I), which is the end-product of highenergy adenosine triphosphatc (ATP) catabolism during reduced oxygen (02) supply/demand states resulting from hypoxia and ischemia.’ In regard to the cardiovascular system, ADO may be considered a self-protective hormone or autocoid, because it is ...
J A, Gatell, H B, Barner, K, Shevde
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Melatonin and myocardial protection

International Journal of Cardiology, 2011
considerations. Circulation 2006;113:2335–62. [5] Sebastian-Gambaro MA, Liron-Hernandez FJ, Fuentes-Arderiu X. Intraand interindividual biological variability data bank. Eur J Clin Chem Clin Biochem 1997;35:845–52. [6] Dominguez-Rodriguez A, Abreu-Gonzalez P, Kaski JC.
Ronit, Lavi, Shahar, Lavi
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Myocardial Protection During Reperfusion

The Thoracic and Cardiovascular Surgeon, 1996
After prolonged periods of energy depletion, myocardial cells may rapidly deteriorate during the early stage of reperfusion. It has now been clearly demonstrated that this kind of acute lethal reperfusion injury is due to specific processes elicited by cellular re-energization.
H M, Piper, B, Siegmund, Y V, Ladilov, K D, Schlüter   +3 more
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Myocardial protection

1999
Abstract The concept of placing new grafts to bypass obstructions in coronary arteries is attractively simple. The objective of every operation should be a technically perfect result without producing myocardial damage. Currently only a minority of surgical patients present with normal left ventricular function; most have damaged ...
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Does Myocardial Protection Work?

2015
These data would suggest that hypothermia combined with potassium cardioplegia enhances protection of the ischemic myocardium over other available techniques. The ideal conduct of this myocardial protection is not yet apparent but certain aspects are worthy of emphasis.
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Polarization and myocardial protection

Current Opinion in Cardiology, 1999
Heart surgery or transplantation generally involve global ischemia, and techniques have been developed to protect the myocardium from ischemic and reperfusion injury. Hyperkalemic cardioplegia has been the gold standard for myocardial protection for years, but patients undergoing surgery almost invariably have some postoperative dysfunction. One factor
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