Results 41 to 50 of about 123,187 (262)
Bivalirudin started during emergency transport for primary PCI. [PDF]
, 2013 BACKGROUND: Bivalirudin, as compared with heparin and glycoprotein IIb/IIIa inhibitors, has been shown to reduce rates of bleeding and death in patients undergoing primary percutaneous coronary intervention (PCI).Berg, J. van den, Bernstein, D., Clayton, T., Clemmensen, P., Coste, P., Deliargyris, E.N., Eggink, G.J., et al., Goldstein, P., Grunsven, P. van, Hamm, C.W., Hamon, M., Hof, A. van't, Huber, K., Lapostolle, F., Nef, H., Nibbe, L., Orto, M. Campo dell', Pocock, S., Prats, J., Schuette, D., Soulat, L., Steg, P.G., Steinmetz, J., Verheugt, F.W.A., Zeymer, U. +25 morecore +1 more sourceInfusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction
Advanced Healthcare Materials, EarlyView.We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman +18 morewiley +1 more sourceEffects of sacubitril/valsartan in the PARADIGM-HF Trial (Prospective Comparison of ARNI with ACEI to Determine Impact on Global Mortality and Morbidity in Heart Failure) according to background therapy [PDF]
, 2016 Background—In the PARADIGM-HF trial (Prospective Comparison of ARNI with ACEI to Determine Impact on Global Mortality and Morbidity in Heart Failure), the angiotensin receptor neprilysin inhibitor sacubitril/valsartan was more effective than the ...Gong, Jianjian, Jhund, Pardeep S., Lefkowitz, Martin P., McMurray, John J.V., Okumura, Naoki, Packer, Milton, Rizkala, Adel R., Rouleau, Jean L., Shi, Victor C., Solomon, Scott D., Swedberg, Karl, Zile, Michael R. +11 morecore +2 more sourcesPAF Triggered Pyroptotic NETosis Aggravates Myocardial Ischemia/Reperfusion Injury
Advanced Science, EarlyView.Platelet activating factor (PAF) secreted by cardiomyocytes during MI/R, drives NETs formation and subsequent NETosis. PAF/NETosis signaling activation is an initiative and causal factor in driving MI/R injury. This study identifies dapagliflozin as a potent NETosis inhibitor, and demonstrates that manipulating PAF‐NETosis signal by dapagliflozin or ...Jiawei Wu, Shule Zhang, Ruofan Du, Lina Kang, Guodong Zhao, Xue Bao, Haochi Yang, Ziqing Xie, Tianyu He, Huiyong Sun, Haiping Hao, Lijuan Cao +11 morewiley +1 more sourceGuidelines for pre-operative cardiac risk assessment and perioperative cardiac management in non-cardiac surgery : the Task Force for Preoperative Cardiac Risk Assessment and Perioperative Cardiac Management in Non-cardiac Surgery of the European Society of Cardiology (ESC) and endorsed by the European Society of Anaesthesiology (ESA) [PDF]
, 2009 Non-cardiac surgery; Pre-operative cardiac risk assessment; Pre-operative cardiac testing; Pre-operative coronary artery revascularization; Perioperative cardiac management; Renal disease; Pulmonary disease; Neurological disease; Anaesthesiology; Post ...Don Poldermans, Jeroen J. Bax, Eric Boersma, Stefan De Hert, Erik Eeckhout, Gerry Fowkes, Bulent Gorenek, Michael G. Hennerici, Bernard Iung, Malte Kelm, Keld Per Kjeldsen, Steen Dalby Kristensen, Jose Lopez-Sendon, Paolo Pelosi, François Philippe, Luc Pierard, Piotr Ponikowski, Jean-Paul Schmid, Olav F.M. Sellevold, Rosa Sicari, Greet Van den Berghe, Frank Vermassen, Sanne E. Hoeks, Ilse Vanhorebeek, Alec Vahanian, Angelo Auricchio, Jeroen J. Bax, Claudio Ceconi, Veronica Dean, Gerasimos Filippatos, Christian Funck-Brentano, Richard Hobbs, Peter Kearney, Theresa McDonagh, Keith McGregor, Bogdan A. Popescu, Zeljko Reiner, Udo Sechtem, Per Anton Sirnes, Michal Tendera, Panos Vardas, Petr Widimsky, Raffaele De Caterina, Stefan Agewall, Nawwar Al Attar, Felicita Andreotti, Stefan D. Anker, Gonzalo Baron-Esquivias, Guy Berkenboom, Laurent Chapoutot, Renata Cifkova, Pompilio Faggiano, Simon Gibbs, Henrik Steen Hansen, Laurence Iserin, Carsten W. Israel, Ran Kornowski, Nekane Murga Eizagaechevarria, Mauro Pepi, Massimo Piepoli, Hans Joachim Priebe, Martin Scherer, Janina Stepinska, David Taggart, Marco Tubaro, Schwartz, Almanaseer, Poldermans, Lee, Boersma, Poldermans, Poldermans, Poldermans, Devereaux, Naughton, Mangano, Ferguson, Carroll, National Center for Health Statistics, Hoeks, Hoeks, Hoeks, Wirthlin, Fleisher, Schouten, Blankensteijn, Holte, Nguyen, Gurusamy, Hlatky, Fletcher, Biccard, Wiklund, Morris, Detsky, Goldman, Maisel, Thygesen, Sabatine, Cannon, Priebe, Tsimikas, Wang, Omland, Bibbins-Domingo, Feringa, Dernellis, Rodseth, Cuthbertson, Cuthbertson, Fox, Jeger, Noordzij, Klocke, Kertai, Etchells, Shaw, Elhendy, Sicari, Das, Nandalur, Rerkpattanapipat, Danias, Hamon, Gerber, Pouleur, Boersma, Reilly, Brunelli, Older, Piepoli, Bassand, Silber, Van de Werf, Cruickshank, Raby, Brady, Juul, Mangano, Yang, Zaugg, Auerbach, McGory, Schouten, Stevens, Bangalore, Devereaux, Wiesbauer, Beattie, Lindenauer, Dunkelgrun, Hoeks, Shammash, Dickstein, Paravastu, van Gestel, Feringa, Boersma, Graham, Rosenson, Hindler, Williams, Durazzo, Schouten, Schouten, Schouten, Coriat, Dodds, Sun, Oosterga, Filion, Wijeysundera, Kertai, Shchukin Iu, Oliver, Wallace, Wijeysundera, Vitez, Macdonald, Shah, Domanski, Lindblad, Robless, Burger, Biondi-Zoccai, Douketis, Vahanian, De Caterina, Pengo, Poldermans, Eagle, Huber, Kaluza, Howard-Alpe, Nuttall, Rabbitts, Douketis, McFalls, Poldermans, Serruys, Kazmers, Hammill, Bhatia, Karagiannis, Feringa, Mancia, Weksler, Iung, Kertai, Vahanian, Habib, Wilson, Forrest, Forrest, Katz, Bertrand, Zipes, Amar, Cox, O'Kelly, Polanczyk, Amar, Atlee, Fuster, Maisel, Balser, Balser, Bayliff, Jakobsen, Mahla, Vardas, Eagle, Gregoratos, Erdman, Potyk, Simon, Shapiro, Madigan, Pinski, Cockcroft, Kertai, Welten, Kheterpal, McCullough, Merten, Maioli, Salem, Murkin, Newman, Selim, Armstrong, Sin, Ramakrishna, Welten, van Gestel, Galiè, Biagini, Leung, Leung, Kaplan, London, Landesberg, Kertai, Landesberg, Martinez, Drew, Landesberg, Fleisher, Mangano, Mangano, London, Eisenberg, Practice guidelines for perioperative transesophageal echocardiography, Polanczyk, Sandham, Feringa, Noordzij, Umpierrez, Vanhorebeek, van den Berghe, Van den Berghe, Gandhi, Ammori, Ellger, Finfer, De Hert, Slogoff, Rodgers, Wu, Bode, Mauermann, Rigg, Birkmeyer, Liu, White, Polomano, Dolin, Jorgensen, Block, Schug +299 morecore +3 more sourcesMechanically Robust Biodegradable Stents With Theragenerative Vascular Responses via Combined 3D Printing and Janus Nanoengineering
Advanced Science, EarlyView.This work introduces a theragenerative 3D‐printed biodegradable stent with Janus nanoarchitecture for spatially controlled vascular healing. A luminal tantalum ion–implanted surface accelerates endothelialization and hemocompatibility, while an abluminal sirolimus/poly‐L‐lactic acid–tantalum layer provides sustained drug release and suppresses smooth ...Jong Hwa Seo, Dong‐Sung Won, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Chan Ho Moon, Ji Won Kim, Yubeen Park, Minho Kang, Dong Yun Lee, Donghyun Lim, Kisuk Yang, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Seokbeom Kim, Jun‐Kyu Park, Jung‐Hoon Park, Hyun‐Do Jung +19 morewiley +1 more sourceInfarct size and left ventricular remodelling after preventive percutaneous coronary intervention [PDF]
, 2016 Objective: We hypothesised that, compared with culprit-only primary percutaneous coronary intervention (PCI), additional preventive PCI in selected patients with ST-elevation myocardial infarction with multivessel disease would not be associated with ...Berry, Colin, Carrick, David, Das, Rajiv, Edwards, Richard J., Eteiba, Hany, Hennigan, Barry W., Mangion, Kenneth, Mason, Maureen, McClure, John, McEntegart, Margaret, Oldroyd, Keith G., Payne, Alexander R., Petrie, Mark C., Wilson, Rebecca +13 morecore +1 more source