Results 111 to 120 of about 430,076 (285)

Allogeneic Human Bone Marrow‐Derived Mesenchymal Stem Cells Accelerate Diabetic Wound Healing via Inflammation Suppression and Angiogenesis Promotion: A Preclinical Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Mesenchymal stem cells (MSCs) have been shown to enhance tissue regeneration and wound healing. This preclinical study investigated the therapeutic potential of human bone marrow‐derived mesenchymal stem cells (hBM‐MSCs) for accelerating diabetic wound healing.
Rong‐Fu Chen, Keng‐Fan Liu, Chia‐Chun Lee, Yu‐Han Chen, Hsin‐Hsin Shen, Yur‐Ren Kuo   +5 more
wiley   +1 more source

Electrocardiographic Imaging of Myocardial Ischemia, Infarction and Scar: Correlation with SPECT, MRI and Arrhythmias

, 2010
This thesis focuses on the development and testing of electrocardiographic (ECG) methods to diagnose and characterize myocardial ischemia, infarction and fibrosis (scar).
Strauss, David G
core   +1 more source

An extracellular matrix paradox in myocardial scar formation [PDF]

Signal Transduction and Targeted Therapy, 2020
Sangkyun Cho, David T. Paik, Joseph C. Wu   +2 more
openaire   +2 more sources

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

Rotating Frame Spin‐Lock Cardiac MRI Method at 9.4 T Can Characterize Diffuse Fibrosis in Progressing Hypertensive Heart Disease in Mice

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose This study aimed to investigate the applicability of rotating frame spin‐lock continuous wave (CW) T1ρ and relaxation along a fictitious field with Rank 2 (RAFF2) methods complementary to native T1 and late gadolinium enhancement (LGE) for cardiac magnetic resonance imaging (CMRI) of diffuse fibrosis in mice with advancing hypertensive
Riku Kiviluoto, Diana Törmä, Ahmed Tawfek, Aleksi Leikas, Eetu Räihä, Mari Merentie, Anna‐Kaisa Ruotsalainen, Seppo Ylä‐Herttuala, Elias Ylä‐Herttuala   +8 more
wiley   +1 more source

Ejection fraction in left bundle branch block is disproportionately reduced in relation to amount of myocardial scar

, 2018
Introduction: The relationship between left ventricular (LV) ejection fraction (EF) and LV myocardial scar can identify potentially reversible causes of LV dysfunction.
Klem, Igor, Arheden, Håkan, Jablonowski, R., Sörensson, Peder, Ugander, M., Sigfridsson, Andreas, Wieslander, Björn, Strauss, David G., Atwater, Brett D., Arheden, H., Engblom, H., Axelsson, J., Atwater, B.D., Schelbert, Erik B., Nijveldt, R., Chaudhry, Uzma, Axelsson, Jimmy, Jablonowski, Robert, Klem, I., Wieslander, B., Engblom, Henrik, Ugander, Martin, Borgquist, R., Nijveldt, Robin, Sorensson, P., Platonov, P.G., Schelbert, E.B., Platonov, Pyotr G., Chaudhry, U., Sigfridsson, A., Borgquist, Rasmus, Strauss, D.G., Schelbert, EB, Arheden, Håkan,, Nijveldt, R, Sorensson, P, Klem, Igor,, Nijveldt, Robin,, Wieslander, Björn,, Atwater, Brett D.,, Platonov, PG, Sigfridsson, Andreas,, Wieslander, B,, Lund University., Schelbert, Erik B.,, Axelsson, J, Klem, I, Engblom, Henrik,, Jablonowski, Robert,, Borgquist, Rasmus,, Ugander, Martin,, Jablonowski, R, Sigfridsson, A, Platonov, Pyotr G.,, Chaudhry, U, Axelsson, Jimmy,, Sörensson, Peder,, Strauss, David G.,, Chaudhry, Uzma,   +58 more
core   +1 more source

Immediate Resumption of Positive Airway Pressure Following Sinus Surgery: A Prospective Controlled Multicenter Study

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Untreated obstructive sleep apnea (OSA) in the perioperative period confers significant cardiopulmonary risk. However, many otolaryngologists defer restarting positive airway pressure (PAP) therapy following functional endoscopic sinus surgery (FESS) due to perceived risk of epistaxis, mucosal injury, and wound healing.
Garret Choby, Jose L. Mattos, Erin K. O'Brien, Devyani Lal, Michael J. Marino, Spencer Payne, Carlos N. Pinheiro‐Neto, Nicholas R. Rowan, Anthony Tang, Eric W. Wang, Janalee Stokken   +10 more
wiley   +1 more source

Role of feature tracking cardiac MRI in evaluation of ischemic cardiomyopathy

The Egyptian Journal of Radiology and Nuclear Medicine
Background Ischemic cardiomyopathy (ICM) is characterized by profound left ventricular (LV) remodelling, impaired systolic function, and variable myocardial viability.
Yomna Abdulwahab Mohamed Rihan, Maha Mohamed Zaki Bilal, Amina Ahmed Sultan, Dina El-Metwally Mansour   +3 more
doaj   +1 more source

Gramine Suppresses Myofibroblast Activation and ECM Accumulation in Renal Fibrosis by Targeting the NF‐κB/NLRP3 and TGF‐β1/Smad Pathways

Phytotherapy Research, EarlyView.
ABSTRACT Chronic kidney disease (CKD) is driven by persistent inflammation and progressive fibrosis, leading to irreversible renal damage. Gramine (GMN), an indole alkaloid, has broad pharmacological benefits. However, its therapeutic potential against renal fibrosis remains unexplored.
Shobhit Gairola, Archana Bhatta, Tushar Mishra, Ravinder K. Kaundal   +3 more
wiley   +1 more source

Treg‐stromal cell axis in tissue repair and autoimmune diseases: Mechanisms and clinical translation

Rheumatology &Autoimmunity, EarlyView.
The Treg‐stromal cell axis as a central regulator of tissue repair and immune tolerance. Under physiological conditions, bidirectional communication between Tregs and stromal cells—mediated by cell‐surface molecular contacts, anti‐inflammatory cytokines, and extracellular vesicles—orchestrates inflammation resolution, immune tolerance, and complete ...
Peiyan Zhang, Rongyuan Gao, Zhaohui Zheng   +2 more
wiley   +1 more source