Results 231 to 240 of about 430,076 (285)

A Rare Case Report on Dedifferentiated Liposarcoma of the Thigh Mimicking an Abscess With Vascular Features: A Diagnostic Challenge With Fatal Outcome

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Dedifferentiated liposarcoma (DDLPS) is an aggressive malignant soft tissue tumor comprising approximately 15%–20% of all liposarcomas. When presenting in the extremities, its atypical clinical and radiological features may mimic vascular or infectious conditions, posing a serious diagnostic challenge that can delay curative intervention. A 60‐
Rashid Shahriar Sazal, Md. Hashibul Hasan Shawon, Mahin Zubaer, Md. Abul Kalam Azad, Khaled Mahbub Murshed, Kazi Ali Aftab   +5 more
wiley   +1 more source

Heart Failure Progression in the Setting of Persistent Atrial Fibrillation, Frequent Premature Ventricular Complexes, and Malignancy‐Related Limitations to Guideline‐Directed Medical Therapy: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
Persistent atrial fibrillation, frequent premature ventricular complexes, and limited tolerance of guideline‐directed medical therapy contributed to progressive ventricular dysfunction, with LVEF declining from approximately 50% to 20%–25%. AV nodal ablation with CRT‐D implantation provided durable ventricular rate control and biventricular pacing.
Douni Roger, Waleed Shaker, Majid Yavari, Rajan Thakur, Mark Castellani, Zan Siddiqi, Maurice Tiotsop   +6 more
wiley   +1 more source

Lactate metabolism and protein lactylation in programmed cell death: From novel mechanism to therapeutic strategies in human diseases

Clinical and Translational Medicine, Volume 16, Issue 10, October 2026.
This review highlights protein lactylation as a metabolic‐epigenetic regulator linking lactate reprogramming to programmed cell death. By modulating histone and non‐histone targets, lactylation reshapes cell fate decisions and represents a promising biomarker and therapeutic target in human diseases.
Yue Chen, Xiwen Wang, Xiuping Wang, Na Lin, Wenjie Wang, Ruiqi Fu, Yutong Wu, Yi Liu, Hengwei Liu   +8 more
wiley   +1 more source

Radiation‐induced AXL upregulation in CCR2+ monocytes promotes cardiac fibrosis

Clinical and Translational Medicine, Volume 16, Issue 10, October 2026.
1. IR_D30 is characterised by established cardiac fibrosis and ongoing immune remodelling. 2. Cardiac CCR2+ monocytes accumulate after irradiation and contribute to fibroblast activation through paracrine signalling. 3. AXL contributes to this fibroblast‐activating activity, at least in part through MEK/ERK signalling. 4.
Ying‐Yi Li, Jian‐Qi Xiong, Zhi‐Hui Zhang, Xin Liu, Yi‐Xin Cheng, Yong‐Xin Chi, Guan‐Qiao Li, Wen‐Huan Zhong, Shuang Chen, Zhen‐Yu He   +9 more
wiley   +1 more source

Association Between HIV Infection Duration and Left Ventricular Concentric Remodeling and Myocardial Fibrosis: A Cross‐Sectional Study Using Cardiac MRI

Journal of Magnetic Resonance Imaging, Volume 64, Issue 4, Page 1037-1049, October 2026.
ABSTRACT Background Antiretroviral therapy has transformed HIV into a chronic condition, yet cardiac injury remains a major issue. Purpose To assess the ability of cardiac MR imaging markers to predict cardiac injury and disease progression in HIV‐infected individuals. Study Type Prospective.
Chunyan Deng, Wei Sun, Tianhu Gao, Haixia Chen, Lu Liu, Ran Li   +5 more
wiley   +1 more source

Fully automated contrast selection of joint bright- and black-blood late gadolinium enhancement imaging for robust myocardial scar assessment.

Magn Reson Imaging
de Villedon de Naide V, Maes JD, Villegas-Martinez M, Ribal I, Maillot A, Ozenne V, Montier G, Boullé T, Sridi S, Gut P, Küstner T, Stuber M, Cochet H, Bustin A.   +13 more
europepmc   +1 more source