Results 51 to 60 of about 430,076 (285)

Real‐World Safety and Effectiveness of JAK Inhibitors in Systemic Sclerosis: A Propensity‐Matched Study From the EUSTAR Cohort

Arthritis Care &Research, EarlyView.
Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato, Marie‐Elise Truchetet, Marco Minerba, Oliver Distler, Juan José Alegre Sancho, Yolanda Braun‐Moscovici, Christina Bergmann, Petros Sfikakis, Jeska K. de Vries‐Bouwstra, Murray Baron, Silvia Bellando‐Randone, Lorenzo Dagna, Christopher P. Denton, Madelon C. Vonk, Vanessa Smith, Ivan Castellvi, Gabriela Riemekasten, Andra Balanescu, Masataka Kuwana, Maria De Santis, Kamal Solanki, Anastas Batalov, Vahan Mukuchyan, Marco Matucci‐Cerinic, Yannick Allanore, Francesco Del Galdo, Michael Hughes, EUSTAR Collaborators   +27 more
wiley   +1 more source

Value of segmental myocardial strain by 2-dimensional strain echocardiography for assessment of scar area induced in a rat model of myocardial infarction

Cardiovascular Ultrasound, 2012
Objectives Two-dimensional strain echocardiography (2DSE) technique has enabled accurate quantification of regional myocardial function. This experimental study was aimed to investigate the value of 2DSE in detection of segmental regional myocardial ...
Liao Shu-sheng, Ruan Qin-yun, Lin Mei-yan, Yan Lei   +3 more
doaj   +1 more source

Microvascular Damage Is Associated With Carotid Wall Structural Changes in Systemic Sclerosis: A Capillaroscopy and Ultrasound‐Based Observational Study

Arthritis Care &Research, EarlyView.
Objective Systemic sclerosis (SSc) is characterized by cardiovascular risk excess not fully explained by traditional factors. Whether the severity of microvascular damage correlates with structural subclinical atherosclerosis remains unclear. We investigated the relationship between nailfold videocapillaroscopy (NVC) abnormalities and carotid ...
Eugenio Capparelli, Luca Clerici, Francesco Lapia, Giusy C. Moltisanti, Eleonora Zaccara, Greta Pellegrino, Daniela Bompane, Francesca Capelli, Letizia Ferrami, Laura Castelnovo, Antonio Tamburello, Maria Sole Chimenti, Paola Faggioli, Antonino Mazzone   +13 more
wiley   +1 more source

Power Modulation Echocardiography to Detect and Quantify Myocardial Scar

Journal of the American Society of Echocardiography, 2022
Myocardial scar correlates with clinical outcomes. Traditionally, late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) is used to detect and quantify scar. In this prospective study using LGE CMR as reference, the authors hypothesized that nonlinear ultrasound imaging, namely, power modulation, can detect and quantify myocardial ...
Papachristidis, Alexandros, Theodoropoulos, Konstantinos C., Marvaki, Apostolia, Queiros, Sandro, D'hooge, Jan, Masoero, Giovanni, Pagnano, Gianpiero, Huang, Marilou, Dancy, Luke, Sado, Daniel, Shah, Ajay M., Murgatroyd, Francis D., Monaghan, Mark J.   +12 more
openaire   +2 more sources

Topically Delivered Treg‐Attracting Microparticle‐Hydrogel Composites Recruit Regulatory T Cells and Limit Cardiac Injury After Severe Ischemia

Advanced Healthcare Materials, EarlyView.
CCL22‐releasing PLGA microparticles (MP) suspended in topically applied hydrogels (HEART) establish a sustained chemokine gradient at the injured myocardium. HEART recruits CCR4+ regulatory T cells, reduces infarct size and graft fibrosis, and improves cardiac function.
Matthew A. Borrelli, Alexis T. Reese, Jordan J. P. Warunek, Betsy Ann Varghese, Canxing Lin, Jeffery J. Baust, Brenda McMahon, Steven R. Little, Hēth R. Turnquist   +8 more
wiley   +1 more source

A Myocardial Scar Threshold Segmentation Algorithm Based on Grey-level Correction

四川大学学报. 自然科学版, 2016
Isolation of the myocardial scar from delayed enhancement cardiac magnetic resonance image (DEMRI) for a qualitative and quantitative assessment is of significant early diagnostic and accurate prognostic value for patients with ischemic heart diseases ...
LI Xiao-Ning, LI Yuan-Jie, ZHANG Hao-Yang, CHEN Yu-Cheng   +3 more
doaj  

Myocardial Scar in Sarcoidosis by 12‐lead ECG and Pathology [PDF]

Annals of Noninvasive Electrocardiology, 2011
This case demonstrates the use of QRS scoring to quantify myocardial scar in a patient with cardiac sarcoidosis and left bundle branch block who progressively received an implantable defibrillator, cardiac resynchronization therapy (CRT), left ventricular assist device and cardiac transplantation.
David G, Strauss, Ronald H, Selvester, Louis R, Dibernardo   +2 more
openaire   +2 more sources

Mapping the infarct scar

, 2017
This case describes late potentials with decremental conduction in post-myocardial infarction ...
Mattias Duytschaever, Hein Heidbuchel, Haran Burri   +2 more
core   +1 more source

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

Advanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang, Yu Dong, Yongsheng Du, Rui Gao, Lin Zhang, Fei Tong   +5 more
wiley   +1 more source

Ectopic Ossification in the Scar Tissue of Rats with Myocardial Infarction

Cell Transplantation, 2006
We describe the occurrence of bone-like formations in the left ventricular wall of infarcted rats treated or not with bone marrow cells injected systemically or locally into the myocardium. The incidence of ectopic calcification in hearts has been reported in rare cases in children with infarcts without previous coronary artery disease.
Karla Consort Ribeiro, Elisabete César Mattos, João Pedro Saar Werneck-de-Castro, Vanessa Pinho Ribeiro, Ricardo Henrique Costa-e-Sousa, Amarildo Miranda, Emerson Lopes Olivares, Marcos Farina, José Geraldo Mill, Regina Coeli dos Santos Goldenberg, Masako Oya Masuda, Antônio Carlos Campos de Carvalho   +11 more
openaire   +4 more sources