Results 141 to 150 of about 103,083 (287)

Coronary Wave Intensity Analysis as an Invasive and Vessel-Specific Index of Myocardial Viability. [PDF]

Circ Cardiovasc Interv, 2022
Ryan M, De Silva K, Morgan H, O'Gallagher K, Demir OM, Rahman H, Ellis H, Dancy L, Sado D, Strange J, Melikian N, Marber M, Shah AM, Chiribiri A, Perera D.   +14 more
europepmc   +1 more source

Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases

Animal Models and Experimental Medicine, EarlyView.
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam, Aashika Raagavi Jeanpierre, Salma Mohammed, Rajesh Srinivasan, Aman Kumar Mohanty   +4 more
wiley   +1 more source

Myocardial viability testing: all STICHed up, or about to be REVIVED? [PDF]

Eur Heart J, 2022
Ryan M, Morgan H, Chiribiri A, Nagel E, Cleland J, Perera D.   +5 more
europepmc   +1 more source

Small vesicles, big potential: A review of innovative exosome delivery and molecular mechanisms in preclinical myocardial infarction models

Animal Models and Experimental Medicine, EarlyView.
This narrative review discusses animal models of exosome‐based myocardial infarction treatments. Emerging techniques aim to improve exosome stability, targeting, and bioavailability for MI treatment as drug delivery vehicles and regenerative mediators that promote myocardial regeneration. Abstract Exosomes have emerged as promising therapeutic carriers,
Chayanisa Phutiyothin, Kovit Pattanapanyasat, Sarawut Kumphune   +2 more
wiley   +1 more source

Role of Late Gadolinium Enhancement in the Assessment of Myocardial Viability. [PDF]

Cureus, 2022
Shah DV, Kalekar DT, Gupta DA, Lamghare DP.   +3 more
europepmc   +1 more source

[Myocardial viability assessment].

Acta medica portuguesa, 2012
The prognosis for patients with chronic coronary artery disease and severe left ventricular dysfunction is poor, despite advances in different therapies. The assessment of myocardial viability has become an important aspect of the diagnosis, prognosis and management of patients with ischemic cardiomyopathy.
Hélder, Fernandes, Alexandra, Sousa, José, Campos, José, Patrício, Patrícia, Oliveira, Tiago, Vieira, Ana, Oliveira, Teresa, Faria, Berta, Perez, Elisabete, Martins, Jorge, Pereira   +10 more
openaire   +1 more source

Multi‐omics data mining combined with experimental validation reveals ferroptosis‐ and autophagy‐associated hub genes as diagnostic candidates and immune modulators in atherosclerosis

Animal Models and Experimental Medicine, EarlyView.
Using the GSE225650 dataset, we performed differential expression gene (DEG) screening, Weighted Gene Coexpression Network Analysis (WGCNA), and immune infiltration profiling on atherosclerosis (AS) samples, yielding 104 shared candidate genes. Subsequently, these 104 candidate genes were intersected with ferroptosis‑ and autophagy‑related gene sets ...
Xinou Zheng, Jinling Zheng, Xuezhuang Li, Hua Chen, Li Zhang, Yuqiong Zhao, Yahao Ling   +6 more
wiley   +1 more source

Myocardial viability assessment and utility in contemporary management of ischemic cardiomyopathy. [PDF]

Clin Cardiol, 2022
Katikireddy CK, Samim A.
europepmc   +1 more source

Astrocytic Mitochondria Transplantation Rescues Neuron Loss and Dendritic Injuries in Acute Cerebral Ischemic Stroke Mouse Model by Flexibly Regulating Mitochondria Dynamics

Annals of Neurology, EarlyView.
Objective Cerebral ischemic stroke causes neuronal oxygen/energy deprivation, disrupting mitochondrial function including reduced membrane potential and bioenergetics, exacerbating neuronal injury. Mitochondrial defects are, therefore, a central neuropathological node and potential therapeutic target.
Ning Bian, Jianing Shen, Linwei Tian, Jinghui Li, Lu Yang, Bo Yuan, Shulin Li, Yuyu Niu, Lu Zhao, Jingkuan Wei   +9 more
wiley   +1 more source

High salt intake damages myocardial viability and induces cardiac remodeling via chronic inflammation in the elderly. [PDF]

Front Cardiovasc Med, 2022
Li K, Song H, Wei F, Liu D, Zhao Y, Yin H, Cui Y, Zhang H, Liu Z.   +8 more
europepmc   +1 more source