Results 221 to 230 of about 103,083 (287)

Multiple organ procurement [PDF]

, 1995
Doyle, HR, Kang, Y, Kormos, RL, Marino, IR, Starzl, TE   +4 more
core  

RBMX Transcriptionally Repressed by EZH2‐Associated H3K27me3 Modification Attenuates Pyroptosis in Renal Ischemia/Reperfusion Injury via Regulating SIRT3/NLRP3 Inflammasome Activation

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ischemic reperfusion injury (IRI) to kidney is a significant clinical factor in acute kidney injury (AKI). This study aimed to investigate the new role of RNA‐binding motif protein X‐linked (RBMX), a modulator of m6A methylation, in renal IRI and to examine the associated regulatory mechanisms. An in vitro renal IRI model was established using
Yi‐Han Wang, Yan Teng, Fang‐Lan Yao, Shu‐Qi Wei, Yan Li   +4 more
wiley   +1 more source

Logistics and management of the multiple organ donor [PDF]

, 1994
Doyle, HR, Marino, IR, Scotti-Foglieni, C, Starzl, TE   +3 more
core  

Early Dapagliflozin and Melatonin Treatment Ameliorated LV Fibrosis via Suppressing TGF‐β1/Smads and Activating Nrf2‐ARE Signaling in MI Rodent

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study tested whether combined dapagliflozin (DAPA) and melatonin (Mel) therapy was superior to merely one for ameliorating the left ventricular (LV) fibrosis/remodeling and improving LV ejection fraction (LVEF) in rats after acute myocardial infarction (AMI). In vitro study demonstrated that DAPA treatment significantly suppressed the TGF‐
Jiunn‐Jye Sheu, Jui‐Ning Yeh, Han‐Tan Chai, John Y. Chiang, Chi‐Ruei Huang, Jun Guo, Hon‐Kan Yip   +6 more
wiley   +1 more source

ZFP36L1 Enhances Microglial Ferroptosis in Ischemic Stroke by Reducing FTO‐Mediated N6‐Methyladenosine Demethylation of ACSL1 mRNA

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Microglia play an important role in ischemic stroke (IS). However, the molecular regulatory mechanisms underlying microglial ferroptosis in IS remain incompletely understood. In this study, blood samples were collected from 20 IS patients and 15 healthy volunteers.
Ai‐Xia Song, Han‐Xu Jin, Yuan‐Xin Sun, Wen‐Hui Kou, Xiao‐Ning Niu, Huan‐Huan Wang, Ting‐Ting Zhong, Ping Gu   +7 more
wiley   +1 more source

Vaccarin Improves Myocardial Ischemia–Reperfusion Injury by Attenuating Oxidative Stress and Ferroptosis Through Reducing NOX4‐Modulated JAK2/STAT3 Pathway Activation

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Vaccarin is a naturally occurring flavonoid glycoside with cardioprotective properties; however, its involvement in myocardial ischemia–reperfusion (MI/R) injury remains poorly defined. We herein investigated whether vaccarin protects cardiomyocytes from MI/R‐induced dysfunction in vivo and in vitro and examined the associated molecular ...
Han Yang, Mi Zhou, Feng‐Cai Zhang
wiley   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

Med Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang, Ge Zhang, Tian‐Ding Liu, Tianshu Gu, Fengyi Yu, Pengyuan Xu, Wunan Mi, Xuanjiang Zhao, Qian Guo, Honglin Zheng, Taiqi Zhao, Qiang Li, Di Lu, Mingxuan Duan, Chaoyang Yu, Ruhao Wu, Shiqian Zhang, Haonan Zhang, Zeyu Wang, Youyang Zheng, Yan Xiao, Zenglei Zhang, Ge Zhang   +22 more
wiley   +1 more source

Dynamic Mode Decomposition (DMD) for Low‐Latency Real‐Time Cardiac MRI

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To demonstrate dynamic mode decomposition (DMD) for high spatiotemporal low‐latency online reconstruction in 2D real‐time cardiac MRI. Methods DMD was applied to 2D spiral balanced steady state free precession (bSSFP) real‐time adult and fetal cardiac MRI at 0.55 T, with data from 10 healthy adult volunteers (3F/7M; age: 21–49; BMI: 20–
Ecrin Yagiz, Bilal Tasdelen, Ibrahim K. Ozaslan, Mihailo R. Jovanovic, Ye Tian, Krishna S. Nayak   +5 more
wiley   +1 more source

Optimized Reduced Field of View and Fat Suppression Methods for Interleaved Multislice In Vivo Cardiac Diffusion Tensor Imaging

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Slice interleaving, a limited phase encode (PE) field of view (FOV), and effective fat suppression are vital for efficient cardiac diffusion tensor imaging (cDTI) with minimal artifacts. This study aimed to optimize reduced FOV and fat suppression methods for interleaved multislice cDTI to improve signal‐to‐noise ratio (SNR) and ...
Yaqing Luo, Pedro F. Ferreira, Ke Wen, Ricardo Wage, Guang Yang, Dudley J. Pennell, Sonia Nielles‐Vallespin, Andrew D. Scott   +7 more
wiley   +1 more source

Faster and More Robust CK Reaction Rate Estimation at 3T Using Acquisition‐Weighted 31P Cardiac 1D‐MRSI With Compartment‐Based Reconstruction

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Quantification of the creatine kinase (CK) forward reaction rate (kf) in the human heart using phosphorus magnetic resonance spectroscopy is clinically important; however, it is limited by long acquisition times, operator subjectivity in analysis, and potential skeletal muscle contamination.
Aaron Axford, Iveta Pajanová, William D. Watson, Andrew C. Tyler, Roshan Xavier, Ferenc E. Mózes, Oliver J. Rider, Damian J. Tyler, Ladislav Valkovič   +8 more
wiley   +1 more source