Results 41 to 50 of about 886,856 (278)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Cardiac PET in the Last Five Years: Established Tracers, Novel Radiopharmaceuticals, and Translational Challenges

Applied Sciences
Cardiac positron emission tomography (PET) has undergone substantial development in recent years, moving beyond conventional perfusion imaging toward a multiparametric and increasingly quantitative assessment of cardiovascular disease.
Agostino Chiaravalloti, Luca Verdesca, Marco Alfonso Perrone, Antonio Chiaravalloti, Daniele Di Biagio   +4 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Myocardial Viability Multimodality Visualization: Ukrainian Cardiovascular Surgeons Association Expert Consensus Guidelines

Український журнал серцево-судинної хірургії, 2022
Myocardial loss due to necrosis in coronary artery disease (CAD) remains the main cause of heart failure. In these circumstances myocardial mass loss severity identification by cardiac visualization and, conversely, myocardial visualization evaluation ...
Vasyl V. Lazoryshynets, Anatoliy V. Rudenko, Svitlana V. Fedkiv, Sergiy V. Potashev, Sergii V. Salo, Oleksandra A. Mazur   +5 more
doaj  

Does myocardial viability detection improve using a novel combined 99mTc sestamibi infusion and low dose dobutamine infusion in high risk ischemic cardiomyopathy patients?

Anatolian Journal of Cardiology, 2020
Objective: Early identification of viable myocardium in ischemic cardiomyopathy (ICM) patients is essential for early intervention and better clinical outcome.
Padma Subramanyam, Shanmuga Sundaram Palaniswamy   +1 more
doaj   +1 more source

Myocardial Viability – An Important Decision Making Factor in the Treatment Protocol for Patients with Ischemic Heart Disease

Acta Medica Bulgarica, 2022
Ischemic heart disease (IHD) affects > 110 million individuals worldwide and represents an important contributor to the rise in the prevalence of heart failure and the associated mortality and morbidity.
Grigorov V., Grigorov M., Grigorov E., Nocheva H.   +3 more
doaj   +1 more source

Effects of Causal Beliefs About Gout on Public Views About Gout Management: A Randomized Experimental Study

Arthritis Care &Research, EarlyView.
Objective Despite well‐described biologic causes, the public views unhealthy lifestyle choices as the primary cause of gout. This study investigated how causal beliefs about gout influence the public's views about its management. Methods In a randomized study, 201 members of the public viewed one of two 2‐minute videos about gout.
Rachel Murdoch, Borislav Mihov, Anne Horne, Keith J. Petrie, Gregory D. Gamble, Lachlan Fleck, Nicola Dalbeth   +6 more
wiley   +1 more source

PET imaging with FDG to guide revascularization in patients with systolic heart failure

The Egyptian Heart Journal, 2013
The assessment of myocardial viability is important in the management of patients with coronary artery disease and left ventricular systolic dysfunction.
Justin R. McCrary, L. Samuel Wann, Randall C. Thompson   +2 more
doaj   +1 more source

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source

A precise oral glucose loading 18F-FDG PET myocardial metabolic imaging protocol in coronary artery disease patients complicated by diabetes mellitus: an exploratory prospective cohort study

Frontiers in Medicine
ObjectivesWe evaluated the feasibility of using a precise oral glucose loading combined with subcutaneous insulin administration protocol for 18F-FDG PET myocardial metabolic imaging in patients with coronary artery disease (CAD) complicated by diabetes ...
Liang Yin, Yangyang Lin, Jianlan Yue, Zhichun Lin, Hongtao Sun   +4 more
doaj   +1 more source