Results 91 to 100 of about 11,460,446 (385)

Microvascular Dysfunction Is Associated With Impaired Myocardial Work in Obstructive and Nonobstructive Hypertrophic Cardiomyopathy: A Multimodality Study

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2022
Background Two‐dimensional speckle tracking echocardiography has been shown to correlate with microvascular dysfunction, a hallmark of hypertrophic cardiomyopathy (HCM).
P. Garcia Brás, S. A. Rosa, I. Cardoso, L. Branco, A. Galrinho, A. Gonçalves, B. Thomas, J. Viegas, A. Fiarresga, G. Branco, R. Pereira, M. Selas, Filipa Silva, I. Cruz, L. Baquero, R. Ferreira, L. R. Lopes   +16 more
semanticscholar   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Work‐Related Outcomes After a Myocardial Infarction [PDF]

, 2004
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90385/1/phco.24.16.1515.50946 ...
Cooper, Jeanna V., Eagle, Kim A., Erickson, Steven R., Kline‐Rogers, Eva M., McBurney, Christopher R., Smith, Dean E.   +5 more
core   +1 more source

Comparison of Myocardial Layer-Specific Strain and Global Myocardial Work Efficiency During Treadmill Exercise Stress in Detecting Significant Coronary Artery Disease

Frontiers in Cardiovascular Medicine, 2022
Background Myocardial layer-specific strain can identify myocardial ischemia. Global myocardial work efficiency (GWE) based on non-invasive left ventricular (LV) pressure-strain loops is a novel parameter to determine LV function considering afterload ...
Jingru Lin, Lijian Gao, Jia He, Mengyi Liu, Yuqi Cai, L. Niu, Ying Zhao, Xiaoni Li, Jiangtao Wang, Weichun Wu, Zhenhui Zhu, Hao Wang   +11 more
semanticscholar   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Deep learning analysis of the myocardium in coronary CT angiography for identification of patients with functionally significant coronary artery stenosis

, 2017
In patients with coronary artery stenoses of intermediate severity, the functional significance needs to be determined. Fractional flow reserve (FFR) measurement, performed during invasive coronary angiography (ICA), is most often used in clinical ...
Išgum, Ivana, Leiner, Tim, Lessmann, Nikolas, van Hamersvelt, Robbert W., Viergever, Max A., Voskuil, Michiel, Wolterink, Jelmer M., Zreik, Majd   +7 more
core   +2 more sources

Strain and Myocardial Work Index during Echo Exercise to Evaluate Myocardial Function in Athletes

Journal of Cardiovascular Echography, 2022
The aim of the study was to evaluate the application of global longitudinal strain (GLS) and myocardial work (MW) at rest and during exercise in healthy sedentary or trained participants, to test their ability to improve echocardiographic information and
D. Borzì, S. Saladino, Valentina Losi, D. Faro, I. Monte   +4 more
semanticscholar   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Long-term cardiovascular consequences of cancer therapy-related cardiac dysfunction: insights from ventricular–arterial coupling and myocardial work [PDF]

Eur Heart J Imaging Methods Pract
Anthony F. Yu, Jessica M. Scott, Jessica Flynn, Chaya S. Moskowitz, Chau T. Dang, Lee Jones, Richard M. Steingart, Jennifer E. Liu   +7 more
openalex   +3 more sources

Myocardial work in electrical dyssynchrony due to left bundle branch block

Российский кардиологический журнал
Aim. To evaluate myocardial function in different groups of patients with left bundle branch block (LBBB) and the LBBB "model" — right ventricular pacing (RVP).Material and methods.
E. M. Rimskaya, S. V. Dobrovolskaya, E. V. Kukharchuk, S. Yu. Kashtanova, N. A. Mironova, G. S. Tarasovsky, A. E. Komlev, T. E. Imaev, M. A. Saidova, S. P. Golitsyn   +9 more
doaj   +1 more source