P1575 Preserved myocardial work efficiency after transcatheter aortic valve implantation-induced left bundle branch block [PDF]
, 2020 Lars Gunnar Klæboe +3 more
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Evaluation of left ventricular myocardial work quantitatively by pressure-strain loop in young strength athletes with different heart rates [PDF]
, 2021 Pengge Li +6 more
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Advanced Science, EarlyView.Normal bladders exhibit quiescent fibroblasts/macrophages, whereas neurogenic bladders show acute‐phase Itga8⁺ fibroblast expansion driven by Trem2⁺ macrophage‐secreted Fn1, which activates FAK/RhoA/ROCK signaling, promotes cytoskeletal remodeling, and upregulates pro‐fibrotic genes.
Jiaxin Wang +9 more
wiley +1 more source
Comparative Analysis of Myocardial Work After Decongestion Therapy in a Patient With Acutely Decompensated HFrEF [PDF]
, 2023 Alexandre Costa Souza +5 more
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Advanced Science, EarlyView.The study shows that noncardiac surgical inflammation rapidly disrupts HDL function and cholesterol efflux in mice and human patients. Impaired reverse cholesterol transport after surgery drives rapid lipid accumulation, NETosis, and apoptosis within atherosclerotic plaques.
Dominique M. Boucher +15 more
wiley +1 more source
XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss
Advanced Science, EarlyView.Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan +13 more
wiley +1 more source
Myocardial Work Efficiency, A Novel Measure of Myocardial Dysfunction, Is Reduced in COVID-19 Patients and Associated With In-Hospital Mortality [PDF]
, 2021 Anum Minhas +9 more
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Advanced Science, EarlyView.The Phospholamban (PLN) R9C mutation reduces SERCA2a binding, increasing calcium recycling and baseline contractility. However, the excess of free PLN promotes pentamer formation, limiting phosphorylation and blunting β‐adrenergic signaling. Under cardiac stress, enhanced functional demands overwhelm proteostasis in PLN R9C cells, leading to misfolded ...
Qi Yu +10 more
wiley +1 more source
Corrigendum: Left Ventricular Strains and Myocardial Work in Adolescents With Anorexia Nervosa
Frontiers in Cardiovascular Medicine, 2022 Justine Paysal +9 more
doaj +1 more source
Adenosine stress myocardial contrast echocardiography combined with myocardial work function in patients with ischemia and nonobstructive coronary artery disease [PDF]
Xuemei Zhang +8 more
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