Results 211 to 220 of about 11,293,345 (337)

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

Advanced Science, EarlyView.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang, Min‐Yu Tsou, Pin‐Hung Li, Jo‐Ching Chen, Yen‐Liang Liu, Gideon Meyerowitz‐Katz, Tsung‐Hsun Tsai, Pen‐Hua Su   +7 more
wiley   +1 more source

Effect of Transcatheter Aortic Valve Implantation on Non-Invasive Myocardial Work Parameters: A Systematic Review and Meta-Analysis. [PDF]

J Clin Med
Leo I, Sicilia F, Sabatino J, Cersosimo A, Carabetta N, Strangio A, Panuccio G, Canino G, Ielapi J, Salerno N, Sorrentino S, Torella D, De Rosa S.   +12 more
europepmc   +1 more source

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source

Did you know? Is there a reserve in myocardial work via the Frank‐Starling mechanism in healthy humans? [PDF]

Meihan Guo, David Montero
openalex   +1 more source

Distribution of myocardial work in arterial hypertension: insights from non-invasive left ventricular pressure-strain relations

, 2020
Filip Lončarić, M Marciniak, L Nunno, M Mimbrero, João Filipe Fernandes, Dora Fabijanović, Laura Sanchís, Adelina Doltra, Sílvia Montserrat, Maja Čikeš, Pablo Lamata, Bart Bijnens, Marta Sitges   +12 more
openalex   +2 more sources

Chaperone‐Mediated Autophagic Degradation of USP9X in Macrophages Exacerbates Postmyocardial Infarction Inflammation and Cardiac Dysfunction

Advanced Science, EarlyView.
This study demonstrates that inflammatory stimuli induce the acetylation‐triggered, chaperone‐mediated autophagic degradation of ubiquitin‐specific peptidase 9 X‐linked (USP9X) in macrophages. USP9X acts as a macrophage “inflammation switch” after myocardial infarction (MI). USP9X loss destabilizes tumor necrosis factor receptor‐associated factor (TRAF)
Biqing Wang, Xiangheng Cai, Mengqi Li, Xue Liu, Junhui Xue, Ye Liu, Ding Ai, Xinyang Hu   +7 more
wiley   +1 more source

Non-invasive left ventricular myocardial work indices in preterm neonates born to mothers with severe preeclampsia in pregnancy. [PDF]

Arch Gynecol Obstet
Chen H, Li X, Sun F, Zhang J, Liu W, Dong X, Li H, Xu Q, Han B.   +8 more
europepmc   +1 more source

A stepwise strategy integrating dynamic stress CT myocardial perfusion and deep learning–based FFRCT in the work-up of stable coronary artery disease [PDF]

Lijuan Lyu, Jichen Pan, Dumin Li, Dexin Yu, Xinhao Li, Wei Yang, Mei Dong, Yeming Han, Yongfeng Liang, Pengfei Zhang, Mei Zhang   +10 more
openalex   +1 more source

Programmable Pentamolecular Cross‐Scale Imaging Reveals the Multiplicative Synergistic Effect of High‐Fat / High‐Salt Diet on Atherosclerosis

Advanced Science, EarlyView.
This study demonstrates multifactorial lifestyle impacts on the pathogenesis and progression of cardiovascular diseases by a nanofluorescence sensor array for detecting four redox species and protein phosphorylation levels. Through cross‐scale fluorescence imaging of rats with different diets, we revealed that compared with single dietary interventions,
Jin Li, Na Zhao, Mengmeng Lu, Ruize Zhao, Wei Zhang, Ping Li, Yue Tang, Wen Zhang, Hui Wang, Bo Tang   +9 more
wiley   +1 more source

The Role of Diastolic Stress Echo and Myocardial Work in Early Detection of Cardiac Dysfunction in Women with Breast Cancer Undergoing Chemotherapy. [PDF]

Biomedicines
Sokratous S, Kyriakou M, Khattab E, Alexandraki A, Fotiou EL, Chrysanthou N, Papakyriakopoulou P, Korakianitis I, Constantinidou A, Kadoglou NPE.   +9 more
europepmc   +1 more source