Results 231 to 240 of about 11,460,446 (385)

Blocking Lysine Crotonylation and Aerobic Glycolysis as Targeting Strategy Against mpox Virus Replication

Advanced Science, EarlyView.
Wei et al. report that MPXV infection induces aerobic glycolysis, a process mediated by the viral protein I3 through lysine crotonylation at its K102 residue. The acetyltransferase MYST1 catalyzes the crotonylation of I3 to inhibit the ubiquitin‐mediated degradation of WDR26.
Pengjun Wei, Zongzheng Zhao, Ruoqi Xu, Qin Yan, Liangzi Jiang, Fuxiao Geng, Yang Gu, Tianjiao Wang, Jing Zhou, Xiao Li, Qin Yan, Chun Lu, Wan Li   +12 more
wiley   +1 more source

Prognostic role of myocardial work in patients with heart failure and reduced ejection fraction treated by sacubitril/valsartan [PDF]

, 2021
Elena Galli, Yanis Bouali, Alban Gallard, Arnaud Hubert, Christophe Leclercq, Erwan Donal   +5 more
openalex   +1 more source

Bifurcate Regulation of Hematopoietic Homeostasis and Bone Osteogenesis by VHL‐HIF2α‐Controlled Adipocyte Function

Advanced Science, EarlyView.
The VHL‐HIF2α (VHL is Von Hippel‐Lindau) axis in adipocytes differentially regulates hematopoiesis and bone formation through stem cell factor (SCF) and chemerin, respectively. This hypoxia‐responsive pathway in adipocytes establishes a systemic signaling network with HSCs and MSCs to maintain tissue homeostasis, revealing a targetable axis for ...
Qian Li, Jia Li, Anshu Tang, Cong Li, Chao Zhang, Congcong Zhang, Yun‐Cai Liu   +6 more
wiley   +1 more source

Peak myocardial work index: a novel nonproprietary approach for the assessment of global constructive myocardial work by strain echocardiography. [PDF]

Int J Cardiovasc Imaging
Chen P, Kiriakou C, Aurich M, Greiner S, Maliandi G, Müller-Hennessen M, Giannitsis E, Meder B, Frey N, Pleger S, Mereles D.   +10 more
europepmc   +1 more source

Investigating myocardial work as a CRT response predictor is not a waste of work [PDF]

European Heart Journal, 2020
Frits W Prinzen, Joost Lumens
openaire   +3 more sources

Redox‐Responsive Tellurium‐Bridged Covalent Organic Frameworks/PEG Composites for Targeted Therapy of Diabetic Cardiomyopathy

Advanced Science, EarlyView.
This study unlocks the immense potential of COF@polymer nanocomposites as a multifunctional therapeutic platform for targeted drug delivery in diabetic cardiomyopathy. Abstract Diabetic cardiomyopathy, a major complication of diabetes, is strongly associated with elevated levels of glycated hemoglobin (HbA1c) and reactive oxygen species (ROS). However,
Jing Xue, Jialu Zhuang, Taotao Fan, Songtao Tang, Junjun Wang, Xiaohui Liu, Jian Liu, Jin Shi, Jiaji Li, Wanjun Li, Danyou Hu, Xiaoqian Zhang, Hua Wang, Guiyang Zhang   +13 more
wiley   +1 more source

Return to Work after Uncomplicated Acute Myocardial Infarction [PDF]

Marie Smith, Brenda Shipley, James Thurston, Timothy M. Moore, Ziyang Wang   +4 more
openalex   +1 more source

Echocardiographic study of myocardial work in elderly type 2 diabetes mellitus patients with microalbuminuria. [PDF]

BMC Geriatr
Wen H, Li H, Hong M, Tian W, Peng L, Chen Y.   +5 more
europepmc   +1 more source

Faecalibaculum rodentium Alleviates Ionizing Radiation‐Induced Damage in Mice by Improving Intestinal Integrity and Hematopoiesis via Its Metabolite Butyrate

Advanced Science, EarlyView.
The model shows the probiotics screening and underlying mechanisms of F. rodentiumn in alleviating IR‐induced tissue injury. Stress‐induced STAT3 mitochondria localization decreases F. rodentium abundance and butyrate concentration. Supplementation of F.
Hanyong Zhu, Hui Guo, Na Sun, Rui Xiao, Binbin Ji, Ruihan Jiang, Fuxing Dong, Chen Yao, Xuerong Wang, Rongqing Li, Jie Zhao, Xueqin Li, Shengzhe Gong, Yongqin Qin, Xin Chen, Yuchen Pan, Takayuki Ikezoe, Jing Yang   +17 more
wiley   +1 more source

Evaluation of the Effect of Myocardial Localisation Errors on Myocardial Blood Flow Estimates from Myocardial Perfusion MRI [PDF]

, 2010
Biglands, J, Boyle, RD, Jerosch-Herold, M, Larghat, A, Magee, D, Plein, S, Radjenovic, A   +6 more
core   +1 more source