Results 61 to 70 of about 11,177,392 (298)

Effect of Sacubitril/Valsartan or Enalapril on Left Ventricular Function in Patients With Hematologic Malignancies Treated With Bone Marrow Transplantation

JACC: Advances
Background: In patients with bone marrow transplantation (BMT) for hematologic malignancies, evidence for prevention of cancer therapy-related cardiac dysfunction (CTRCD) remains limited.
Konstantinos Katogiannis, MD, PhD, Ignatios Ikonomidis, MD, PhD, Dimitrios Farmakis, MD, PhD, John Thymis, MD, PhD, Maria Stamouli, MD, PhD, Georgia Aggeliki Koliou, MSc, George Makavos, MD, PhD, Damianos Tsilivarakis, MD, Dionisios Vythoulkas, PhD, Panagiotis Tsirigotis, MD, PhD   +9 more
doaj   +1 more source

Incremental value of non-invasive myocardial work for the evaluation and prediction of coronary microvascular dysfunction in angina with no obstructive coronary artery disease

Frontiers in Cardiovascular Medicine, 2023
BackgroundEvidence suggests that patients suffering from angina with no obstructive coronary artery disease (ANOCA) experience coronary microvascular dysfunction (CMD).
Ying Li, Dandan Sun, Hanzhang Zhao, Zhiyan Qin, Wei Ji, Wei Ji, Huihui Zhang, Ni Jiao, Bo Luan, Mingyan Ding, Fang Zhu   +10 more
doaj   +1 more source

Long-term cardiovascular consequences of cancer therapy-related cardiac dysfunction: insights from ventricular-arterial coupling and myocardial work. [PDF]

Eur Heart J Imaging Methods Pract
Yu AF, Scott JM, Flynn J, Moskowitz CS, Dang CT, Jones LW, Steingart RM, Liu JE.   +7 more
europepmc   +3 more sources

Microvascular Dysfunction Is Associated With Impaired Myocardial Work in Obstructive and Nonobstructive Hypertrophic Cardiomyopathy: A Multimodality Study

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2022
Background Two‐dimensional speckle tracking echocardiography has been shown to correlate with microvascular dysfunction, a hallmark of hypertrophic cardiomyopathy (HCM).
P. Garcia Brás, S. A. Rosa, I. Cardoso, L. Branco, A. Galrinho, A. Gonçalves, B. Thomas, J. Viegas, A. Fiarresga, G. Branco, R. Pereira, M. Selas, Filipa Silva, I. Cruz, L. Baquero, R. Ferreira, L. R. Lopes   +16 more
semanticscholar   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Myocardial Injury in Multiple Myeloma Patients With Preserved Left Ventricular Ejection Fraction: Noninvasive Left Ventricular Pressure-Strain Myocardial Work

Frontiers in Cardiovascular Medicine, 2022
Introduction Over one-half of patients with multiple myeloma (MM) die of heart failure or arrhythmia. Left ventricular ejection fraction (LVEF) is used to describe left ventricular systolic function.
Zhiyue Liu, Li Zhang, Mei Liu, Fang Wang, Yanqiu Xiong, Zhuoqin Tang, Qian Li, Qiuchen Lu, Shichu Liang, T. Niu, He Huang   +10 more
semanticscholar   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Comparison of Myocardial Layer-Specific Strain and Global Myocardial Work Efficiency During Treadmill Exercise Stress in Detecting Significant Coronary Artery Disease

Frontiers in Cardiovascular Medicine, 2022
Background Myocardial layer-specific strain can identify myocardial ischemia. Global myocardial work efficiency (GWE) based on non-invasive left ventricular (LV) pressure-strain loops is a novel parameter to determine LV function considering afterload ...
Jingru Lin, Lijian Gao, Jia He, Mengyi Liu, Yuqi Cai, L. Niu, Ying Zhao, Xiaoni Li, Jiangtao Wang, Weichun Wu, Zhenhui Zhu, Hao Wang   +11 more
semanticscholar   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Myocardial work in electrical dyssynchrony due to left bundle branch block

Российский кардиологический журнал
Aim. To evaluate myocardial function in different groups of patients with left bundle branch block (LBBB) and the LBBB "model" — right ventricular pacing (RVP).Material and methods.
E. M. Rimskaya, S. V. Dobrovolskaya, E. V. Kukharchuk, S. Yu. Kashtanova, N. A. Mironova, G. S. Tarasovsky, A. E. Komlev, T. E. Imaev, M. A. Saidova, S. P. Golitsyn   +9 more
doaj   +1 more source