Results 331 to 340 of about 177,501 (382)

MiR-425-5p intervenes in autoimmune myocarditis by regulating Treg cell differentiation through NRAS. [PDF]

Front Cell Dev Biol
Zhou S, Zhang L, Duan X, Liu K, Yingnan Y, Ma M, Han B.   +6 more
europepmc   +1 more source

Trametinib alters contractility of paediatric Noonan syndrome‐associated hypertrophic myocardial tissue slices

ESC Heart Failure, Volume 12, Issue 3, Page 2321-2334, June 2025.
Abstract Aims No curative treatment is available for RASopathy‐associated childhood‐onset hypertrophic cardiomyopathy (RAS‐CM). Preclinical data and individual reports suggest a beneficial effect of small molecules targeting the RAS–mitogen‐activated protein (MAP) kinase (MAPK) pathway in severely affected RAS‐CM patients.
Jules Hamers, Payel Sen, Sarala Raj Murthi, Laura Papanakli, Maria von Stumm, Francesca Baessato, Julie Cleuziou, Christian Meierhofer, Peter Ewert, Andreas Dendorfer, Daphne Merkus, Cordula M. Wolf   +11 more
wiley   +1 more source

Severe Parvovirus B19-Associated Myocarditis in Children in the Post-COVID-19 Era: A Multicenter Observational Cohort Study. [PDF]

Open Forum Infect Dis
Russell N, Hatcher J, Best T, Breuer J, Charlesworth J, Muir P, Vipond B, Paulus S, Saxena R, Simmonds J, Vergnano S, Davis P, Kadambari S.   +12 more
europepmc   +1 more source

A stochastic probability model to quantify the risk of transmission of foot and mouth disease virus at the wildlife/livestock interface of Kruger national park, South Africa [PDF]

, 2010
Etter, Eric, Gummow, Bruce, Jori, Ferran, Vosloo, Wilna   +3 more
core  

In heart failure, echocardiographic parameters of right ventricular function are powerful tools to predict renal failure

ESC Heart Failure, Volume 12, Issue 3, Page 2310-2320, June 2025.
Abstract Background Chronic kidney disease (CKD) has a high prevalence in patients with heart failure (HF) and is associated with prolonged hospitalization, increased need for intensive care and mortality. There is an urgent need to identify factors that influence the interaction between heart and kidney disorders, often described as cardiorenal ...
Alexander Reinecke, Paulina Dißmann, Norbert Frey, Oliver J. Müller, Hatim Seoudy, Johanne Frank, Derk Frank, Martina E. Spehlmann   +7 more
wiley   +1 more source

ICI-induced cardiovascular toxicity: mechanisms and immune reprogramming therapeutic strategies. [PDF]

Front Immunol
Zheng J, Yi Y, Tian T, Luo S, Liang X, Bai Y.   +5 more
europepmc   +1 more source

Discovery of miRNAs unique to actively transcribed erythroparvovirus infection in heart failure patients

ESC Heart Failure, Volume 12, Issue 3, Page 1872-1882, June 2025.
Abstract Aims miRNAs, small non‐coding RNAs, play key roles in gene regulation, cell differentiation and tissue development. They influence viral infection outcomes by directly interacting with viral genomes or modifying the host microenvironment. This study demonstrates miRNAs' ability to selectively suppress transcriptionally active erythroparvovirus,
Ganna Aleshcheva, Sara Salih, Christian Baumeier, Felicitas Escher, C. Thomas Bock, Heinz‐Peter Schultheiss   +5 more
wiley   +1 more source

Distinctive clinical traits of lupus-related myocarditis: a multicentre retrospective study. [PDF]

Rheumatology (Oxford)
Ramirez GA, Holopainen NEA, Gerosa M, De Luca G, Bellocchi C, Arroyo-Sánchez D, Sala S, Peretto G, Moroni L, Mastropaolo F, Argolini LM, Pizzetti G, Palmisano A, Esposito A, Cariddi A, Sartorelli S, Campochiaro C, Beretta L, Bozzolo EP, Caporali R, Dagna L.   +20 more
europepmc   +1 more source

Relaxin mimetic in pulmonary hypertension associated with left heart disease: Design and rationale of Re‐PHIRE

ESC Heart Failure, Volume 12, Issue 3, Page 1956-1964, June 2025.
Abstract Aims Despite receiving guideline‐directed medical heart failure (HF) therapy, patients with pulmonary hypertension associated with left heart disease (PH‐LHD) experience higher mortality and hospitalization rates than the general HF population.
Marcin Ufnal, Kathleen Connolly, Marcus Millegard, Elena Surkova, Marco Guazzi, Diana Bonderman, Justin Ezekowitz, Finn Gustafsson, Michał Ciurzyński, Raquel López Vilella, Tariq Ahmad, Roy Gardner, Pavel Jansa, Sandra van Wijk, Koichiro Kinugawa, Erik Björklund, Zhi‐Cheng Jing, Stephan Rosenkranz   +17 more
wiley   +1 more source

Severe immune-mediated myocarditis caused by sintilimab combined with gemcitabine: a case report and literature review. [PDF]

Front Cardiovasc Med
Yang H, Sun M, Zhou X, Han Y, Zhang S, Zhang K, Zhang X.   +6 more
europepmc   +1 more source