Results 191 to 200 of about 26,691 (226)

MyoD−E12 Heterodimers and MyoD−MyoD Homodimers Are Equally Stable

Biochemistry, 1997
Muscle development is controlled by the MyoD family of basic helix-loop-helix (bHLH) DNA-binding proteins. These proteins dimerize with ubiquitous products of the E2A gene (E12 and E47) and bind in a sequence-specific manner to enhancer regions of muscle-specific genes activating their expression.
S J, Maleki, C A, Royer, B K, Hurlburt
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MyoD and the transcriptional control of myogenesis

Seminars in Cell & Developmental Biology, 2005
The basic helix-loop-helix myogenic regulatory factors MyoD, Myf5, myogenin and MRF4 have critical roles in skeletal muscle development. Together with the Mef2 proteins and E proteins, these transcription factors are responsible for coordinating muscle-specific gene expression in the developing embryo.
Berkes, Charlotte A., Tapscott, Stephen J.   +1 more
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Jmjd2C increases MyoD transcriptional activity through inhibiting G9a-dependent MyoD degradation

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2015
Skeletal muscle cell differentiation requires a family of proteins called myogenic regulatory factors (MRFs) to which MyoD belongs. The activity of MyoD is under epigenetic regulation, however, the molecular mechanism by which histone KMTs and KDMs regulate MyoD transcriptional activity through methylation remains to be determined.
Eun-Shil Jung, Ye-Ji Sim, Hoe-Su Jeong, Su-Jin Kim, Ye-Jin Yun, Joo-Hoon Song, Su-Hee Jeon, Chungyoul Choe, Kyung-Tae Park, Chang-Hoon Kim, Kye-Seong Kim   +10 more
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MyoD and Regulation of Prostaglandin H Synthase

Experimental Cell Research, 1993
MM14 myoblasts, in contrast to their differentiation defective variant (DD-1) cells, do not synthesize detectable levels of prostaglandins or of the initial enzyme in the pathway of prostaglandin synthesis, prostaglandin H synthase (PGHS) but do exhibit readily detectable level of PGHS mRNA (Steiner, S., et al., 1991, Exp. Cell Res. 192, 643).
J R, Wolf, Y, Hu, R R, Hirschhorn, S M, Steiner   +3 more
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Hypermethylated Myoblasts Specifically Deficient in MyoD Autoactivation as a Consequence of Instability of MyoD

Experimental Cell Research, 1996
MyoD is one of a family of basic helix loop helix (bHLH) transcription factors acting as master switches of skeletal muscle differentiation. In addition to transcriptionally activating differentiation-specific genes, it autoactivates its own expression through a positive feedback loop. It was cloned following the observation that treatment with the DNA
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Rat Monoclonal Antibody Specific for MyoD

Hybridoma, 2010
Myogenic determination 1 (MyoD) is a myogenic regulatory factor (MRF) possessing a basic domain and a helix-loop-helix domain. MRFs play a critical role in myoblast fate and terminal differentiation. MyoD is a transcriptional factor that induces transcription by binding with gene regulatory factors expressed in skeletal muscle.
Akihito, Harada, Yasuyuki, Ohkawa, Shinpei, Ao, Jun, Odawara, Seiji, Okada, Masayuki, Azuma, Yuko, Nishiyama, Mako, Nakamura, Taro, Tachibana   +8 more
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MyoD and myogenesis in C. elegans

BioEssays, 1995
AbstractOne of the goals in developmental biology is the identification of key regulatory genes that govern the transition of embryonic cells from a pluripotent potential to a specific, committed cell fate. During vertebrate skeletal myogenesis, this transition is regulated by the MyoD family of genes. C.
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MyoD: A Regulatory Gene of Skeletal Myogenesis

1990
MyoD is expressed only in skeletal muscle (1), and could be considered a master regulatory gene of myogenesis. When expressed in non-muscle cells, MyoD converts those cells to myoblasts (2). Specifically, the mouse fibroblast cell line 10T1/2 does not express either MyoD or any of several muscle specific genes. Forced expression of MyoD in l0Tl/2 cells
S J, Tapscott, R L, Davis, A B, Lassar, H, Weintraub   +3 more
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MyoD and the paradoxes of myogenesis

Current Biology, 1992
E N, Olson, W M, Perry
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Distribution and Molecular Diversity of Paranoplocephala kalelai (Tenora, Haukisalmi & Henttonen, 1985) Tenora, Murai & Vaucher, 1986 in Voles (Rodentia: Myodes) in Eurasia

Diversity, 2022
S A Abramov, Sergey Konyaev, Egor Vlasov   +2 more
exaly