Results 91 to 100 of about 31,118 (262)

Secretopathies emerge as a new class of neurocristopathies

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira, Cassandra Millet‐Boureima, Joshua A. Moore, Loydie A. Jerome‐Majewska   +3 more
wiley   +1 more source

Convergent innate immune and regulated cell-death pathways in selected myopathies

Frontiers in Immunology
Myopathies are a heterogeneous group of skeletal muscle disorders caused by genetic mutations or acquired insults, including inflammation, infection, endocrine imbalance, and toxic exposure. Myopathies affect a substantial number of individuals worldwide
Moe Yamashita, Moe Yamashita, Jaewoo Park, Sehee Park, Hae Ji Kang, Yoon-Seok Chung, Seon Ah Lim, SangJoon Lee, SangJoon Lee   +8 more
doaj   +1 more source

Myopathy [PDF]

Proceedings of the Royal Society of Medicine, 1936
openaire   +2 more sources

Proteomic profiling of Elp1‐deficient trigeminal ganglia reveals disruption of neurotrophic and metabolic pathways in a familial dysautonomia mouse model

Developmental Dynamics, EarlyView.
Abstract Background Elp1, a subunit of the Elongator complex, is essential for tRNA modification and neuronal development. Mutations in ELP1 underlie familial dysautonomia (FD), a disorder marked by sensory and autonomic neuropathy. While loss of Elp1 disrupts trigeminal ganglion formation and survival, the downstream molecular consequences remain ...
Carrie E. Leonard, Lauren Clarissa Tang, Beatrix Ueberheide, Lisa A. Taneyhill   +3 more
wiley   +1 more source

Role of selenium in the pathophysiology of cardiorenal anaemia syndrome

ESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai, Minoru Yasukawa, Shigeru Shibata   +2 more
wiley   +1 more source

Editorial: Avian Muscle Development and Growth Mechanisms: Association With Muscle Myopathies and Meat Quality Volume II

Frontiers in Physiology, 2021
Massimiliano Petracci, Sandra G. Velleman   +1 more
doaj   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Editorial: Imaging of Neuromuscular Diseases

Frontiers in Neurology, 2021
Jordi Diaz-Manera, Anna Pichiecchio, Anna Pichiecchio, Francesco Santini, Francesco Santini, Francesco Santini, Massimiliano Filosto, Massimiliano Filosto   +7 more
doaj   +1 more source

Repurposed Nrf2 activator dimethyl fumarate rescues muscle inflammation and fibrosis in an aggravated mdx mouse model of Duchenne muscular dystrophy

Redox Biology
In inherited neuromuscular disease, Duchenne muscular dystrophy (DMD), glucocorticoids significantly slow disease progression yet impart side effects severe enough to preclude use in a significant proportion of patients. Extending our findings that acute
Stephanie Kourakis, Cara A. Timpani, Ryan M. Bagaric, Bo Qi, Benazir A. Ali, Rebecca Boyer, Guinevere Spiesberger, Nitika Kandhari, Xu Yan, Jujiao Kuang, Ankita Tulangekar, Judy B. de Haan, Deanna Deveson-Lucas, Nicole Stupka, Dirk Fischer, Emma Rybalka   +15 more
doaj   +1 more source

Muscle Abnormalities in Nonhospitalised Patients With Post–COVID‐19 Condition

Journal of Cachexia, Sarcopenia and Muscle
Background Post‐COVID condition (PCC) affects ~10% of SARS‐CoV‐2–infected individuals and manifests as persistent symptoms such as fatigue, exercise intolerance and muscle weakness.
Andrea Tryfonos, Gustav Jörnåker, Håkan Rundqvist, Kaveh Pourhamidi, Michael Melin, Helena Wallin, Filip J. Larsen, Spyridon Pantelios, Anders P. Mutvei, Veronika Tillander, Uwe J. F. Tietge, Sergio Perez Diaz, Douglas Crafoord, Alen Lovric, Rodrigo Fernandez‐Gonzalo, Eric Rullman, Per Stål, Thomas Gustafsson, Helene Rundqvist, Tommy R. Lundberg   +19 more
doaj   +1 more source