Results 181 to 190 of about 99,848 (257)

Collagen Type VI Alpha 1 as a Regulator of Redox Homeostasis in Antioxidant‐Enhanced Osteogenesis of Dental Stem Cells

open access: yesCell Proliferation, EarlyView.
Under physiological conditions, NAC activates the PI3K‐AKT‐COL6A1 axis to sustain redox balance and enhance osteogenesis. COL6A1 deficiency, however, compromises this axis, inducing oxidative stress and impairing NAC's osteogenic efficacy. ABSTRACT Alveolar bone injury represents a prevalent clinical challenge in dentistry, for which stem cell‐based ...
Zhaosong Meng   +11 more
wiley   +1 more source

ACTA1-Related Adult-Onset Scapuloperoneal Myopathy With Cores and Rods. [PDF]

open access: yesNeuropathol Appl Neurobiol
Caramizaru A   +10 more
europepmc   +1 more source

Hypercortisolism: Causes, Consequences and Clinical Significance – A Review of Pathophysiology

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Hypercortisolism or Cushing syndrome is a heterogeneous clinical spectrum caused by chronic glucocorticoid excess, ranging from exogenous Cushing syndrome to rare endogenous aetiologies and the increasingly recognised entity of mild autonomous cortisol secretion (MACS). Physiological cortisol production is tightly regulated by the hypothalamic–
Mohamed Eldib   +3 more
wiley   +1 more source

Early recognition and successful management of dermatomyositis-systemic lupus erythematosus overlap syndrome: case study of a young adult. [PDF]

open access: yesAnn Med Surg (Lond)
Shivashankar T   +10 more
europepmc   +1 more source

Hypercortisolism: An Under‐Recognised Pathway Linked to Multi‐System Complications

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT The clinical understanding of hypercortisolism (HC) has evolved from a classic overt syndrome with florid Cushingoid features to a broader spectrum of disease that includes milder presentations, often referred to as mild autonomous cortisol secretion (MACS).
Hernan Daniel Sacoto, Vivian A. Fonseca
wiley   +1 more source

Case Report: Overlap syndrome with concurrent polymyositis, masticatory myositis, and lymphocytic thyroiditis in a dog. [PDF]

open access: yesFront Vet Sci
Crawford-Jennings MI   +7 more
europepmc   +1 more source

Is Hypercortisolism Treatable? Which Patients Should Be Treated and How—A Practical Guide for Clinicians

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To provide a practical guide on when to suspect endogenous hypercortisolism, how to use the overnight 1‐mg dexamethasone suppression test (DST) for targeted case‐finding, and which patients are most likely to benefit from treatment.
Juan Pablo Frias
wiley   +1 more source

Nicotinamide riboside prevents mitochondrial dysfunction in nemaline myopathy type 6. [PDF]

open access: yesHum Mol Genet
Baelde RJ   +16 more
europepmc   +1 more source

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