Results 11 to 20 of about 183,642 (350)
A multistate transition model for statin‐induced myopathy and statin discontinuation
CPT: Pharmacometrics & Systems Pharmacology, 2021 The overarching goal of this study was to simultaneously model the dynamic relationships among statin exposure, statin discontinuation, and potentially statin‐related myopathic outcomes.
Yuxi Zhu +9 more
doaj +2 more sources
JACC: Basic to Translational Science, 2019 Summary: This paper discusses the evolving concept of atrial myopathy by presenting how it develops and how it affects the properties of the atria. It also reviews the complex relationships among atrial myopathy, atrial fibrillation (AF), and stroke ...
Mark J. Shen, MD +2 more
doaj +4 more sources
Current Opinion in Neurology, 2014 Purpose of reviewOur aim is to highlight major advances reported in the last few years in drug-induced muscle toxicity.Recent findingsOur focus is on myopathies induced by statins and immune checkpoint inhibitors with a brief overview of rare steroid myopathies.
Mamatha, Pasnoor +2 more
openaire +3 more sources
Altered splicing of the BIN1 muscle-specific exon in humans and dogs with highly progressive centronuclear myopathy [PDF]
, 2013 Amphiphysin 2, encoded by BIN1, is a key factor for membrane sensing and remodelling in different cell types. Homozygous BIN1 mutations in ubiquitously expressed exons are associated with autosomal recessive centronuclear myopathy (CNM), a mildly ...
A Buj-Bello +58 more
core +7 more sources
Aquaporin-4 expression in distal myopathy with rimmed vacuoles
BMC Neurology, 2012 Background Distal myopathy with rimmed vacuoles/hereditary inclusion body myopathy is clinically characterized by the early involvement of distal leg muscles. The striking pathological features of the myopathy are muscle fibers with rimmed vacuoles.
Hoshi Akihiko +5 more
doaj +1 more source
A Case of Statin-Associated Autoimmune Myopathy. [PDF]
, 2017 A 70-year-old previously independent man developed progressive proximal leg weakness resulting in a fall at home suffering traumatic brain injury. He was prescribed a statin medication two years prior, but this was discontinued on admission to the ...
Dokukin, Andrei N +6 more
core +3 more sources
A rare structural myopathy: nemaline myopathy [PDF]
Türk Pediatri Arşivi, 2018 Nemaline myopathy, which is characterized by the accumulation of ''rod'' bodies in muscle fibers is a very rare inherited muscle disease. According to the underlying mutation, the disease has varying severity of clinical outcomes. Patients with severe forms of the disease die because of hypotonia, feeding difficulties, aspiration pneumonia, and ...
Yeşilbaş, Osman +7 more
openaire +2 more sources
Chloroquine and Hydroxychloroquine Myopathy: Clinical Spectrum and Treatment Outcomes
Frontiers in Neurology, 2021 Chloroquine (CQ) and hydroxychloroquine (HCQ) have been associated with muscle toxicity, mostly described as a proximal myopathy with evidence of lysosomal dysfunction on muscle biopsy.
Elie Naddaf +2 more
doaj +1 more source
Journal of the Saudi Heart Association, 2019 A well-known side effect of statin therapy is myopathy. We report a case of statin induced necrotizing autoimmune myopathy, a rare variant of statin-induced myopathy. A 64-year-old gentleman on atorvastatin presented with muscle weakness.
Yehia Saleh +3 more
doaj +1 more source
Lower Limb Radiology of Distal Myopathy due to the S60F Myotilin Mutation [PDF]
, 2009 Distal myopathies are a clinically and genetically heterogenous group of disorders in which the distal limb musculature is selectively or disproportionately affected.
Birchall, Daniel +8 more
core +1 more source