Results 71 to 80 of about 15,976 (198)

Characterization of retinal pigment epithelium layer in healthy and diseased retinas with high‐resolution adaptive optics transscleral flood illumination imaging

Acta Ophthalmologica, EarlyView.
Abstract Purpose The retinal pigment epithelium (RPE) is critical in the pathophysiology of retinal diseases, such as age‐related macular degeneration. Adaptive optics transscleral flood illumination (AO‐TFI) offers rapid, detailed morphometric characterization of the RPE layer.
Leila Sara Eppenberger, Safa Mohanna, Sohrab Ferdowsi, Sonja Simon‐Zoula, Oliver Pfäffli, Christoph Amstutz, Lucas M. Bachmann, Michael A. Thiel, Martin K. Schmid   +8 more
wiley   +1 more source

Axial length, myopia progression, and myopic maculopathy in Stickler syndrome

Acta Ophthalmologica, EarlyView.
Abstract Purpose We lack knowledge on the potentially progressive nature of and the prevalence of complications to myopia as a characteristic trait of Stickler syndrome. Methods This cross‐sectional study combines ophthalmic examination and medical record data on Danish patients with genetically confirmed Stickler syndrome type 1 (COL2A1) and type 2 ...
Kirstine B. Boysen, Mette Bertelsen, Nanna D. Rendtorff, Stense Farholt, Line Kessel   +4 more
wiley   +1 more source

Aqueous Concentrations of Vascular Endothelial Growth Factor in Eyes with High Myopia with and without Choroidal Neovascularization

Journal of Ophthalmology, 2013
Purpose. To investigate aqueous concentrations of vascular endothelial growth factor (VEGF) in eyes with myopic choroidal neovascularization (CNV). Methods.
Taku Wakabayashi, Yasushi Ikuno, Yusuke Oshima, Toshimitsu Hamasaki, Kohji Nishida   +4 more
doaj   +1 more source

Longitudinal changes in choroidal thickness in high myopia: Correlation with maculopathy progression and visual outcomes

Acta Ophthalmologica, EarlyView.
Abstract Purpose To evaluate longitudinal changes in choroidal thickness (CT) in highly myopic eyes and their correlation with myopic maculopathy progression and visual outcomes. Methods Retrospective cohort study on 1228 eyes from 781 highly myopic patients with a minimum 5‐year follow‐up (mean 11.5 ± 3.1 years).
Matteo Mario Carlà, Francesco Boselli, Federico Giannuzzi, Emanuele Crincoli, Fiammetta Catania, Agnese Maria Perugini, Gloria Gambini, Stanislao Rizzo, Carlos Mateo   +8 more
wiley   +1 more source

Changes in choroidal and retinal thickness 6 months before and during 18 months of orthokeratology lens treatment in myopic children

Acta Ophthalmologica, EarlyView.
Abstract Purpose To investigate changes in choroidal and retinal thickness before and during myopia control treatment with orthokeratology lenses (OKL) in myopic children. Methods This was a sub‐study of CONTROL and CONTROL2 studies. The present study was a 2‐year, prospective, single‐group interventional study consisting of a 6‐month pre‐treatment ...
P. O. Hansen, F. Møller, T. M. Jakobsen
wiley   +1 more source

Incidence, predictors and re-treatment outcomes of recurrent myopic choroidal neo-vascularization.

PLoS ONE, 2022
ObjectivesTo evaluate incidence, predictors, and re-treatment outcome of recurrent myopic choroidal neovascularization (m-CNV).MethodsRetrospective consecutive observational series.
Mukesh Jain, Raja Narayanan, Priya Jana, Ashik Mohamed, Rajiv Raman, Pavan Verkicharla, Srikanta Kumar Padhy, Anthony Vipin Das, Jay Chhablani   +8 more
doaj   +1 more source

Factors determining the compliance of patients receiving anti-VEGF therapy for macular diseases with long-term follow-up in real-life practice

Российский офтальмологический журнал, 2021
Purpose: to identify statistically significant factors that determine adherence to long-term follow-up on the part of patients receiving anti-VEGF therapy for macular diseases.Material and methods.
E. V. Bobykin, V. Y. Krokhalev, R. V. Buslaev, O. V. Morozova   +3 more
doaj   +1 more source

MSC‐Derived Exosomal lnc‐AGT‐3: A Novel Anti‐Angiogenic Target in Age‐Related Macular Degeneration Through p53 Signaling Pathway

Aging Cell, Volume 25, Issue 2, February 2026.
MSC‐derived exosomes deliver lnc‐AGT‐3 to vascular endothelial cells, where it binds hnRNP K in the nucleus. This interaction inhibits p53 ubiquitination, enhancing p53 stabilization and transcriptional activation of anti‐angiogenic targets TSP1. Consequently, p53‐mediated signaling is potentiated, effectively suppressing choroidal neovascularization ...
Lingjie Kong, Xiaoyan Han, Siyi Qi, Duo Li, Jingyue Zhang, Linyu Zhang, Shujie Zhang, Qin Jiang, Biao Yan, Chen Zhao   +9 more
wiley   +1 more source

A comparative study of OCT findings in low and high myopia

Journal of the Egyptian Ophthalmological Society, 2020
Aim This study aimed to compare macular findings between low and high myopia. Patients and methods In all, 60 myopic eyes were included in this study. They were divided according to refraction into low myopia of less than or equal −6 SD and high myopia ...
Tarek M Abdalla, Amr I Elawamry, Ossama T Nada, Mariam R Helal   +3 more
doaj   +1 more source

Long-term outcomes of anti-vascular endothelial growth factor therapy with and without posterior scleral reinforcement on myopic maculopathy in myopic choroidal neovascularization eyes

BMC Ophthalmology
Background Anti-vascular endothelial growth factor (anti-VEGF) therapy is used for myopic choroidal neovascularization (mCNV). Patchy chorioretinal atrophy (pCRA) enlargement has been reported in mCNV cases associated with vision loss.
Mengtian Kang, Ningli Wang, Wenjun Xu, Mayinuer Yusufu, Wu Liu, Jiaxin Tian, Yue Qi   +6 more
semanticscholar   +1 more source