Results 121 to 130 of about 45,547 (280)

Incidence, severity and potential pathomechanism of immune‐related pruritus in melanoma patients undergoing immune checkpoint inhibitor therapy

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Pruritus is a frequent cutaneous immune‐related adverse event (irAE) associated with immune checkpoint inhibitors (ICI), impacting patients' quality of life. This study investigates the incidence, severity and management of pruritus in melanoma patients treated with ICI.
Andrea Roggo, Nikolina Ivanovic, Patrick Turko, Lukas Kraehenbuehl, Mitchell Levesque, Reinhard Dummer, Barbara Meier‐Schiesser   +6 more
wiley   +1 more source

Adult and juvenile-onset inflammatory myopathy: autoantibodies and muscle MRI in a cohort of Egyptian patients

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery
Background Idiopathic inflammatory myopathies are a group of autoimmune conditions primarily affecting the proximal muscles and can involve other organs, such as the skin, joints, and lungs. Many diagnostic and classification criteria have been suggested
Yosra Fahmy Eid, Abeer Elsayed Shehab, Dahlia Abdel Mohsen Hussein, Nagia Aly Fahmy   +3 more
doaj   +1 more source

Walsh & Hoyt: Idiopathic Myositis

, 2005
Idiopathic myositis affecting the extraocular muscles usually occurs as an isolated phenomenon unassociated with systemic disease. In some cases, however, orbital myositisis part of a systemic process. Myositis limited to the orbit.
Paul H. Phillips, MD
core  

Increased Risk of Myositis-Specific and Myositis-Associated Autoantibodies After COVID-19 Pandemic and Vaccination: A Spanish Multicenter Collaborative Study

Background: Emerging evidence suggests that SARS-CoV-2 infection and vaccines may trigger autoimmune responses in predisposed individuals. Idiopathic inflammatory myopathies (IIMs) are diseases with diverse clinical manifestations, often associated with ...
Candelas Rodríguez, Gloria Del Mar, García Bravo, Laura, Sánchez Ramón, Silvia María, Fernández Arquero, Miguel, Ochoa Grullón, Juliana   +4 more
core   +1 more source

Comminuted fractures of the proximal phalanx in horses: A multicentre retrospective review

Equine Veterinary Education, EarlyView.
Summary Background Comminuted fractures of the proximal phalanx (CFPP), defined as the presence of three or more major fracture fragments, present difficult management challenges. Feedback from practitioners and long‐term follow‐up can be helpful to reassess evidence‐based treatment strategies and improve clinical outcomes.
C. de Chaisemartin, M. Farfan, B. Dal Cero, A. Martens, F. Rossignol, A. Kalinovskiy, C. Lischer, C. Tessier, S. Grulke, G. Manneveau, V. Gouzer, G. Gomez, J. Samsel, C. Mespoulhes‐Riviere, F. Pichereau, L. Alfonso Gracia Calvo, M. Trécu, A. Spadaro Rossello, P. Planes, X. Peyrecave, C. Mansuy, C. Henry‐Perin, A. Guezennec, M. C. Schramme   +23 more
wiley   +1 more source

The 2025 ATS/ERS update of the international multidisciplinary classification of the interstitial pneumonias: implications for the pathologist

Histopathology, EarlyView.
This review highlights changes relevant to pathologists in the updated multidisciplinary classification of interstitial pneumonias. Changes include expansion beyond idiopathic disease, subclassification as interstitial (fibrotic vs non‐fibrotic) and alveolar filling disorders, expansion to include additional patterns (e.g.
Andrew G Nicholson, Wendy A. Cooper, Aurelie Fabre, William Travis, Lida P. Hariri, Ayodeji Adegunsoye, Sara Piciucchi, Christopher J Ryerson   +7 more
wiley   +1 more source

Diagnostic utility of inflammatory markers in formalin‐fixed and paraffin‐embedded muscle biopsies for idiopathic inflammatory myopathies

Histopathology, EarlyView.
Formalin‐fixed, paraffin‐embedded (FFPE) muscle tissue supports robust immunohistochemical detection of MHC II, MxA, and p62 with performance comparable to frozen sections. This approach reliably identifies the pathological signatures of inclusion body myositis, dermatomyositis, immune‐mediated necrotizing myopathy, and overlap myositis, enhancing the ...
Chinnawut Suriyonplengsaeng, Jariya Waisayarat   +1 more
wiley   +1 more source

A szerológiai csoportosítás és a gyógytorna jelentősége idiopathiás inflammatorikus myopathiákban

, 2014
Kutatásunknak két fő célja volt. Első, hogy a klinikopathológiai klasszifikáció figyelembevétele mellett további szerológiai csoportosítást végezzünk myositis-specifikus antitest (MSA) pozitivitás alapján.
Farkas, Flóra
core  

Evolving treatments for Sjögren disease: current approaches and emerging targets

Internal Medicine Journal, EarlyView.
Abstract Sjögren disease (SjD) is a prevalent systemic autoimmune condition characterised by exocrine gland dysfunction, systemic inflammation and heterogeneous organ involvement. Current management remains largely symptomatic, with no approved disease‐modifying therapies available and substantial unmet clinical need. However, advances in understanding
Mansi Bhurani, Adrian Y. S. Lee, Maureen Rischmueller, Alberta Hoi   +3 more
wiley   +1 more source

Nailfold capillaroscopy in myositis: A case series

SAGE Open Medical Case Reports
Nailfold capillaroscopy is well established in systemic sclerosis; however, abnormalities (scleroderma or scleroderma-like patterns) are identified in other connective tissue diseases, such as myositis, even in the absence of Raynaud’s phenomenon ...
Thaisa Cotton, Marie Hudson, Yves Troyanov, Valérie Leclair, Geneviève Gyger   +4 more
doaj   +1 more source