Results 151 to 160 of about 62,398 (280)
ACR Open Rheumatology, Volume 8, Issue 3, March 2026.Objective Juvenile‐onset systemic sclerosis (jSSc) is a rare, heterogeneous pediatric autoimmune disease. Existing severity tools are often adapted from adult systemic sclerosis and lack pediatric‐specific validation. The Juvenile Systemic Sclerosis Severity Score (J4S) was developed to address this gap by capturing multiorgan disease burden.
Samantha A. Branton, Kathryn S. Torok
wiley +1 more source
ACR Open Rheumatology, Volume 8, Issue 3, March 2026.Objective To assess the predictive performance of inflammatory biomarkers, including C‐reactive protein (CRP) and Krebs von den Lungen 6 (KL‐6), for the development of progressive pulmonary fibrosis (PPF) in patients with systemic sclerosis (SSc)–associated interstitial lung disease (ILD).
Keina Yomono +3 more
wiley +1 more source
Osmolytes as mediators of the muscle tissue’s responses to inflammation : emerging regulators of myositis with therapeutic potential [PDF]
, 2017 Chronic inflammation of skeletal muscle tissues termed myositis is associated with inherited muscular dystrophy and with acquired inflammatory myopathy.
De Paepe, Boel
core +1 more source
Click Chemistry and Bioorthogonal Reaction for Aggregation‐Induced Emission Bioconjugates
Aggregate, Volume 7, Issue 3, March 2026.This review highlights the construction of AIE active bioconjugates via click chemical or bioorthogonal reactions, and their applications in biosensing, bioimaging, and image‐guided treatment. The challenges and perspectives in the area are also discussed.
Xinzhe Yang +3 more
wiley +1 more source
Case‐Based Immunology: B Cells and Systemic Sclerosis Interstitial Lung Disease
Arthritis &Rheumatology, Volume 78, Issue 3, Page 566-581, March 2026.Interstitial lung disease (ILD) is an important complication of systemic sclerosis (SSc), with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to US Food and Drug Administration–approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of ILDs of other systemic autoimmune
Nina Goldman +2 more
wiley +1 more source
Transition From Juvenile Dermatomyositis to Spondyloarthritis: A Novel Overlapping Inflammatory Phenotype [PDF]
ACR Open RheumatolObjective Juvenile dermatomyositis (JDM) is a rare childhood inflammatory myopathy, whereas spondyloarthritis (SpA) is an inflammatory arthropathy characterized by enthesitis and peripheral or axial involvement. We describe a series of patients diagnosed with JDM in childhood who later fulfilled classification criteria for SpA, a sequential phenotype ...
Grooms A +3 more
europepmc +2 more sources
Arthritis &Rheumatology, Volume 78, Issue 3, Page 592-602, March 2026.Objective The optimal treatment strategy for rheumatoid arthritis–associated interstitial lung disease (RA‐ILD) remains uncertain, and direct comparative data between biologics are limited. This study aimed to evaluate the effectiveness and safety of abatacept compared with rituximab in patients with RA‐ILD.
Po‐Cheng Shih +2 more
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Clinical Case Reports, Volume 14, Issue 3, March 2026.ABSTRACT Anti‐synthetase syndrome (ASS) is a rare autoimmune disorder of idiopathic inflammatory myopathy spectrum, characterized by the presence of aminoacyl‐tRNA synthetase antibodies, most commonly anti‐Jo‐1. Clinically presents with interstitial lung disease (ILD), myositis, and arthritis, and may be confused with other autoimmune conditions such ...
Ali Gohar +7 more
wiley +1 more source
IJU Case Reports, Volume 9, Issue 2, March 2026.ABSTRACT Introduction Anti‐melanoma differentiation‐associated gene 5 antibody‐positive interstitial lung disease is a rare but fatal adverse event following immune checkpoint inhibitor treatment for cancers. However, such cases have not been previously reported in patients with urothelial carcinoma.
Akira Saito +4 more
wiley +1 more source