Results 181 to 190 of about 92,434 (342)

First‐Line Therapy in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: A Retrospective, Multicenter, Real‐World Study

open access: yesHead &Neck, Volume 47, Issue 11, Page 2939-2949, November 2025.
ABSTRACT Background In Europe, pembrolizumab with or without chemotherapy is the recommended first‐line treatment for recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC), with a combined positive score (CPS) ≥ 1. In France, the TPExtreme (TPEx) regimen is preferred for CPS < 1.
Alizée Simon   +6 more
wiley   +1 more source

Good's Syndrome Presenting With Weaning Failure From Ventilation and Myasthenia Gravis in a Post‐Thymectomy Patient

open access: yesRespirology Case Reports, Volume 13, Issue 11, November 2025.
This case highlights the importance of long‐term vigilance in patients with thymoma, even after apparently successful resection, as Good's syndrome may manifest years later. Clinicians should maintain a high index of suspicion for Good's syndrome in any thymectomized patient presenting with unexplained infections, diarrhoea, or autoimmune complications,
Asmita Anilkumar Mehta   +4 more
wiley   +1 more source

Myositis-specific and myositis-associated autoantibodies: their clinical characteristics and potential pathogenic roles

open access: yesImmunological Medicine
In recent years, various myositis-specific and myositis-associated autoantibodies have been identified in idiopathic inflammatory myopathies, including dermatomyositis (DM), anti-synthetase syndrome (ASS), immune-mediated necrotizing myopathy (IMNM), and
Mariko Ogawa-Momohara, Yoshinao Muro
doaj   +1 more source

Testicular Function After Immune‐Checkpoint Inhibitors Treatment

open access: yesClinical Endocrinology, Volume 103, Issue 5, Page 721-728, November 2025.
ABSTRACT Objective To investigate the effects of immune‐checkpoint inhibitors (ICIs) on spermatogenesis and testicular endocrine function in reproductive‐age men with melanoma. Design Prospective, mixed longitudinal and cross‐sectional cohort study. Patients Twenty‐nine men aged 19–46 years undergoing ICI therapy for melanoma at two Australian centres ...
Andrea Boutros   +8 more
wiley   +1 more source

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