Results 51 to 60 of about 1,793 (201)
Rheumatology &Autoimmunity, Volume 5, Issue 1, Page 28-36, March 2025.Fibrodysplasia ossificans progressiva, a rare genetic disorder caused by ACVR1 mutations, leads to soft tissue ossification. Recent advancements, including food and drug administration‐approved palovarotene, show promise despite safety concerns. Therapies like tofacitinib and imatinib demonstrate potential, but larger, controlled trials are essential ...
Muhammad Ikrama +6 more
wiley +1 more source
Calcinosis Universalis of the Elbow: A Rare Case with Classical Presentation
Case Reports in Orthopedics, Volume 2015, Issue 1, 2015., 2015 Juvenile Dermatomyositis (JDM) is a rare autoimmune disease in children and adolescents. In these patients calcinosis might be the most characteristic symptom. However there are only few reported cases of intramuscular calcinosis in Dermatomyositis. We report a case of calcinosis universalis (CU) of the elbow in JDM successfully treated with broaching.
Sebastian Philipp Boelch +5 more
wiley +1 more source
An unusual case of bowel obstruction in emergency surgery: The heterotopic mesenteric ossification [PDF]
, 2020 The heterotopic mesenteric ossification, also known as myositis ossificans, is a rare form of heterotopic ossification, a metaplastic phenomenon where new bone is formed in the mesenteric base, generally after abdominal trauma (surgical or other).
Caramaschi, Stefani +6 more
core +2 more sources
Molecular, Phenotypic Aspects and Therapeutic Horizons of Rare Genetic Bone Disorders
BioMed Research International, Volume 2014, Issue 1, 2014., 2014 A rare disease afflicts less than 200,000 individuals, according to the National Organization for Rare Diseases (NORD) of the United States. Over 6,000 rare disorders affect approximately 1 in 10 Americans. Rare genetic bone disorders remain the major causes of disability in US patients.
Taha Faruqi +7 more
wiley +1 more source
Miositis osificante progresiva: ultraestructura, bioquímica e histoquímica de músculo macroscópicamente sano [PDF]
, 1995 Se estudió un caso de miositis osificante progresiva en una niña de 13 años, a la cual se le tomó una muestra de músculo gastronecmio lateral, aparentemente no afectado, en el curso de una intervención quirúrgica ortopédica.
Finol, Héctor J. +4 more
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Fibrodysplasia ossificans progressiva: a case report [PDF]
, 2017 Fibrodysplasia Ossificans Progressiva is a rare debilitating disorder of the musculoskeletal system affecting one in two million individuals. It is characterized by progressive extraskeletal ossification of soft tissues resulting in the original skeleton
Baidoo, Richard O., Dayie, Makafui S.
core +2 more sources
Animal models of tendon calcification: Past, present, and future
Animal Models and Experimental Medicine, Volume 7, Issue 4, Page 471-483, August 2024.Various modeling methods for experimental animal models of tendon calcification are shown in the figure: the methods of modeling tendon calcification in experimental animals as shown in the figure can be mainly classified as trauma induced, tissue factor injections, dietary or pharmacological modifications, and gene knockouts.
Ruichen Li +8 more
wiley +1 more source
Biological activity of a genetically modified BMP-2 variant with inhibitory activity [PDF]
, 2009 Background Alterations of the binding epitopes of bone morphogenetic protein-2 (BMP-2) lead to a modified interaction with the ectodomains of BMP receptors.
Klammert, Uwe +6 more
core +3 more sources
A new spontaneous model of fibrodysplasia ossificans progressiva. [PDF]
, 2010 Fibrodisplasia ossificante progressiva (FOP) é uma doença genética caracterizada por uma acentuada, progressiva e aparentemente incontrolável ossificação dos tendões, ligamentos, faciais e músculos estriados da formação de osso heterotópico resultando na
Martin, Larry D. +2 more
core +3 more sources
Heterotopic Ossification: Cellular Basis, Symptoms, and Treatment [PDF]
, 2012 Heterotopic ossification (HO) is the process by which calcified bone develops in soft tissues. Because of the abnormal calcification, complications such as bone deformation, loss of range of motion, and joint immobility adversely affect patients.
Wolfe, Brian
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