Results 51 to 60 of about 1,762 (159)

Future of fibrodysplasia ossificans progressiva management: A systematic review of investigational therapies

Rheumatology &Autoimmunity, Volume 5, Issue 1, Page 28-36, March 2025.
Fibrodysplasia ossificans progressiva, a rare genetic disorder caused by ACVR1 mutations, leads to soft tissue ossification. Recent advancements, including food and drug administration‐approved palovarotene, show promise despite safety concerns. Therapies like tofacitinib and imatinib demonstrate potential, but larger, controlled trials are essential ...
Muhammad Ikrama, Muhammad Usama, Shifa Israr, Maryam Humayon, Muhammad Umair Javaid, Shafqat Abbas, Muhammad Aliyan Haider   +6 more
wiley   +1 more source

Calcinosis Universalis of the Elbow: A Rare Case with Classical Presentation

Case Reports in Orthopedics, Volume 2015, Issue 1, 2015., 2015
Juvenile Dermatomyositis (JDM) is a rare autoimmune disease in children and adolescents. In these patients calcinosis might be the most characteristic symptom. However there are only few reported cases of intramuscular calcinosis in Dermatomyositis. We report a case of calcinosis universalis (CU) of the elbow in JDM successfully treated with broaching.
Sebastian Philipp Boelch, Thomas Barthel, Sascha Goebel, Maximilian Rudert, Piet Plumhoff, Athanassios Papanikolaou   +5 more
wiley   +1 more source

An unusual case of bowel obstruction in emergency surgery: The heterotopic mesenteric ossification [PDF]

, 2020
The heterotopic mesenteric ossification, also known as myositis ossificans, is a rare form of heterotopic ossification, a metaplastic phenomenon where new bone is formed in the mesenteric base, generally after abdominal trauma (surgical or other).
Caramaschi, Stefani, De Ruvo, Nicola, Farinetti, Alberto, Gelmini, Roberta, Mattioli, Anna Vittoria, Ricciardolo, Andrea Aurelio, Serra, Francesco   +6 more
core   +2 more sources

Molecular, Phenotypic Aspects and Therapeutic Horizons of Rare Genetic Bone Disorders

BioMed Research International, Volume 2014, Issue 1, 2014., 2014
A rare disease afflicts less than 200,000 individuals, according to the National Organization for Rare Diseases (NORD) of the United States. Over 6,000 rare disorders affect approximately 1 in 10 Americans. Rare genetic bone disorders remain the major causes of disability in US patients.
Taha Faruqi, Naveen Dhawan, Jaya Bahl, Vineet Gupta, Shivani Vohra, Khin Tu, Samir M. Abdelmagid, Vasiliki Galani   +7 more
wiley   +1 more source

Calcinosis in juvenile dermatomyositis, a therapeutic challenge [PDF]

, 2007
Calcinosis is a common and debilitating complication of dermatomyositis. It is a hallmark of the disease, occurring mainly in pediatric patients. Little is known about its pathophysiology, and there is no universally recognized treatment.
Castro, Tânia Caroline Monteiro de, Hilário, Maria Odete Esteves, Len, Claudio Arnaldo, Terreri, Maria Teresa Ramos Ascensão, Yamashita, Edson   +4 more
core   +3 more sources

When Limb Surgery Has Become the Only Life-Saving Therapy in FOP: A Case Report and Systematic Review of the Literature [PDF]

, 2020
Fibrodysplasia ossificans progressiva (FOP) is a rare disease in which heterotopic ossification (HO) is formed in muscles, tendons and ligaments. Traumatic events, including surgery, are discouraged as this is known to trigger a flare-up with risk of ...
Botman, Esmée, Bravenboer, Nathalie, Coen Netelenbos, J, de Graaf, Pim, de Vries, Ralph, Eekhoff, Elisabeth M W, Grunwald, Zvi, Lubbers, Wouter D, Micha, Dimitra, Nieuwenhuijzen, Jakko A, Peters, Edgar J G, Raijmakers, Pieter G H M, Sabelis, Louise, Schober, Patrick R, Schwarte, Lothar A, Smilde, Bernard J, Smit, Jan Maerten, Teunissen, Bernd P, Treurniet, Sanne, van Schie, Annelies, Visser, Marieke   +20 more
core   +2 more sources

Animal models of tendon calcification: Past, present, and future

Animal Models and Experimental Medicine, Volume 7, Issue 4, Page 471-483, August 2024.
Various modeling methods for experimental animal models of tendon calcification are shown in the figure: the methods of modeling tendon calcification in experimental animals as shown in the figure can be mainly classified as trauma induced, tissue factor injections, dietary or pharmacological modifications, and gene knockouts.
Ruichen Li, Canhao Lai, Hong Luo, Yujian Lan, Xinfang Duan, Dingsu Bao, Zhipeng Hou, Huan Liu, Shijie Fu   +8 more
wiley   +1 more source

Surgical excision of post-traumatic myositis ossificans of the adductor longus in a football player [PDF]

, 2020
A football player was diagnosed with myositis ossificans of his right adductor longus muscle after an acute injury. Conservative treatment failed and 1 year after the initial trauma the patient underwent surgical excision of a large ossification.
Buijk, S.E. (Steven E.), Smet, G.H.J. de, Weir, A. (Adam)   +2 more
core   +3 more sources

Miositis osificante progresiva: ultraestructura, bioquímica e histoquímica de músculo macroscópicamente sano [PDF]

, 1995
Se estudió un caso de miositis osificante progresiva en una niña de 13 años, a la cual se le tomó una muestra de músculo gastronecmio lateral, aparentemente no afectado, en el curso de una intervención quirúrgica ortopédica.
Finol, Héctor J., Garmendia, J., Hernández, N., Martínez Conde, A., Torres, S.H.   +4 more
core  

گزارش 1 مورد بيمار مبتلا به فيبروديسپلازی(ميوزيت) اسيفيکان پيشرونده [PDF]

, 2003
فيبروپلازی(ميوزيت) اسيفيکان پيشرونده بيماری نادر بافت همبند می‌باشد که مشخصه آن استخوان‌سازی نابجا در نسج نرم و بطور منتشر در تمام بدن و هالوکس والگوس دوطرفه هيپوپلاستيک(انگشت شست کوچک در پا) می‌باشد.
شيرانی, فاطمه
core