Results 71 to 80 of about 26,572 (220)
Can human pluripotent stem cell-derived cardiomyocytes advance understanding of muscular dystrophies? [PDF]
, 2016 Muscular dystrophies (MDs) are clinically and molecularly a highly heterogeneous group of single-gene disorders that primarily affect striated muscles.
Denning, Chris +2 more
core +4 more sources
Narcolepsy and rapid eye movement sleep
Journal of Sleep Research, Volume 34, Issue 2, April 2025.Summary Since the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Francesco Biscarini +4 more
wiley +1 more source
Depression in Myotonic Dystrophy type 1: clinical and neuronal correlates [PDF]
, 2010 Background This study was designed to investigate the prevalence and correlates of depression in Myotonic dystrophy type 1 (DM1). Methods Thirty-one patients with DM1 and 47 subjects in a clinical contrast group, consisting of other neuromuscular ...
Stefan Winblad +4 more
core +1 more source
Journal of Sleep Research, EarlyView.ABSTRACT Multiple sclerosis is frequently associated with sleep disorders. This study aimed to evaluate subjective and objective sleep parameters in de novo relapsing–remitting multiple sclerosis patients compared to healthy controls and to explore correlations with cerebrospinal fluid cytokines.
A. Romigi +10 more
wiley +1 more source
Identification of plant-derived alkaloids with therapeutic potential for myotonic dystrophy type I [PDF]
, 2016 Myotonic dystrophy type I (DM1) is a disabling neuromuscular disease with no causal treatment available. This disease is caused by expanded CTG trinucleotide repeats in the 3 UTR of the dystrophia myotonica protein kinase gene. On the RNA level, expanded
Erne, B. +9 more
core +1 more source
Journal of Medical Genetics, 2002 As with the second edition of this book, published back in 1989, this third edition is an excellent account of clinical and scientific aspects of myotonic dystrophy. The book is easy to read, sustaining this reviewer’s attention to scan the whole book in a single sitting, while subsequently being of value as a reference for closer consultation on ...
openaire +1 more source
Senolytics and exercise: Dual modalities for rejuvenating muscle
The Journal of Physiology, EarlyView.Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican +4 more
wiley +1 more source
IDMC-6 - The Sixth International Myotonic Dystrophy Consortium Meeting
European Journal of Histochemistry, 2009 In 1992 three groups of investigators found that myotonic dystrophy of Steinert, classical myotonic dystrophy, now known as myotonic dystrophy type 1 (DM1), results from an unstable CTG repeat expansion in the non-coding 3’ region of serinethreonine ...
G Meola
doaj +1 more source
Pediatric Obesity, Volume 21, Issue 4, April 2026.ABSTRACT Background Nutritional care in Duchenne muscular dystrophy (DMD), a progressive neuromuscular disorder, is particularly important due to the high risk of obesity in childhood and malnutrition in adolescence. Objectives The study aimed to evaluate metabolic complications in DMD, such as liver USS (ultrasound scan) abnormalities and abnormal ...
Karolina Śledzińska +14 more
wiley +1 more source