Results 61 to 70 of about 3,408 (171)

Chronic model of tympanic perforation in rats with mitomycin C and dexamethasone

open access: yesJournal of Otology, 2019
A rat model of chronic tympanic membrane perforation was developed to be used in the search of new materials for the sealing of these perforations.
Tomás Esteban   +5 more
doaj   +1 more source

Expanding the SIAH1‐Associated Phenotypic Spectrum: Insights From Loss‐of‐Function Variants

open access: yesAmerican Journal of Medical Genetics Part A, Volume 197, Issue 8, August 2025.
ABSTRACT SIAH1 encodes for a RING‐type E3 ubiquitin ligase involved in protein ubiquitination. More specifically, it positively regulates Wnt signaling through promoting the accumulation of β‐catenin and mediates ubiquitination and degradation of Akt3 in neural development.
Liza Douiev   +14 more
wiley   +1 more source

A New EP300 ‐Related Syndrome With Prominent Developmental and Immune Phenotypes

open access: yesAmerican Journal of Medical Genetics Part A, Volume 197, Issue 8, August 2025.
ABSTRACT Rubinstein Taybi syndrome (RTS) is a disorder of chromatin remodeling and transcriptional regulation caused by heterozygous pathogenic variants in CREBBP and EP300. RTS is characterized by a distinct facial gestalt, intellectual disability, structural kidney and heart differences, feeding difficulties, and broad thumbs and great toes ...
Devi Priyanka Maripuri   +3 more
wiley   +1 more source

Hyperbaric oxygen therapy services at the Pamela Youde Nethersole Eastern Hospital hyperbaric oxygen therapy Center: A retrospective epidemiological study

open access: yesHong Kong Journal of Emergency Medicine, Volume 32, Issue 4, August 2025.
Abstract Introduction The aim of this retrospective epidemiological study is to analyze the characteristics and caseload of patients treated at the Pamela Youde Nethersole Eastern Hospital (PYNEH) hyperbaric oxygen therapy (HBOT) Center in Hong Kong from 2018 to 2023 to gain insight into the HBOT service provision and development in HK.
Kin Bong Tang   +2 more
wiley   +1 more source

Otorrhea as a Sign of Medical Treatment Failure in Acute Otitis Media

open access: yesPediatrics and Neonatology, 2013
We report two children with otitis media who developed facial palsy despite prompt antibiotic therapy. Brain images revealed silent mastoiditis. Persistent otorrhea may be a cautious sign of medical treatment failure or complication of acute otitis media,
Tzu-Chun Tsai   +4 more
doaj   +1 more source

Septic Arthritis of the Temporomandibular Joint Secondary to Acute Otitis Media in an Adult: A Rare Case with Achromobacter xylosoxidans

open access: yesCase Reports in Otolaryngology, 2017
Septic arthritis of the temporomandibular joint (SATMJ) is a rare complication of acute otitis media (AOM) with only four reported cases in the English and Japanese literature.
Ryan Chin Taw Cheong, Laura Harding
doaj   +1 more source

Comparison of Three Methods Used in the Diagnosis of Extraesophageal Reflux in Children with Chronic Otitis Media with Effusion

open access: yesGastroenterology Research and Practice, 2015
Objectives. Detection of extraesophageal reflux (EER) in children with chronic otitis media with effusion (OME) using three different diagnostic methods. Methods.
Martin Formánek   +5 more
doaj   +1 more source

CLINICAL AND TYMPANOMETRIC ASSESSMENT OF MIDDLE EAR EFFUSION VERSUS MYRINGOTOMY FINDING

open access: yesمجلة كلية الطب, 2008
Background: The present study was planned to show the accuracy of clinical examination and tympanometry in diagnosis of middle ear effusion. Patients and Methods: The study involved 80 patients (160 ears )suspected to have otitis media with effusion (OME)
Hamed M. Mohammed   +3 more
doaj   +1 more source

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