Results 261 to 270 of about 122,056 (334)

Durvalumab with or without tremelimumab vs platinum-based chemotherapy as first-line treatment for metastatic non-small cell lung cancer: MYSTIC

Annals of Oncology, 2018
N. Rizvi, B. Cho, N. Reinmuth, K. Lee, M. Ahn, A. Luft, M. V. D. Heuvel, M. Cobo, A. Smolin, D. Vicente, V. Moiseyenko, S. Antonia, S. Moulec, G. Robinet, R. Natale, K. Nakagawa, Luping Zhao, P. Stockman, V. Chand, S. Peters   +19 more
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Abstract CT074: Tumor mutational burden (TMB) as a biomarker of survival in metastatic non-small cell lung cancer (mNSCLC): Blood and tissue TMB analysis from MYSTIC, a Phase III study of first-line durvalumab ± tremelimumab vs chemotherapy.

Clinical Trials, 2019
Background High TMB is predictive of PFS benefit with anti-PD-(L)1 ± anti-CTLA-4 therapy in mNSCLC. Preliminary results from MYSTIC (NCT02453282), an open-label, Phase III trial of first-line durvalumab (D; anti-PD-L1), ± tremelimumab (T; anti-CTLA-4 ...
S. Peters, B. Cho, N. Reinmuth, K. Lee, Alexander Luft, M. Ahn, P. Baas, M. C. Dols, A. Smolin, D. Vicente, V. Moiseyenko, S. Antonia, K. Nakagawa, S. Goldberg, Edward J. Kim, R. Raja, P. Brohawn, D. Clemett, P. Thiyagarajah, Urban J. Scheuring, Feng Liu, N. Rizvi   +21 more
semanticscholar   +1 more source

Blood tumor mutational burden (bTMB) and tumor PD-L1 as predictive biomarkers of survival in MYSTIC: First-line durvalumab (D) ± tremelimumab (T) versus chemotherapy (CT) in metastatic (m) NSCLC.

Journal of Clinical Oncology, 2019
9016 Background: MYSTIC, an open-label, Ph3 trial of first-line D (anti-PD-L1) ± T (anti-CTLA-4) vs platinum-based CT, showed an improvement in OS with D vs CT in pts with tumor cell PD-L1 expression ≥25% (PD-L1 TC ≥25%; HR 0.76 [97.54% CI 0.56–1.02], p =
N. Rizvi, B. Cho, N. Reinmuth, K. Lee, A. Luft, M. Ahn, Michel M. van den Heuvel, M. C. Dols, D. Vicente, A. Smolin, V. Moiseyenko, S. Antonia, K. Nakagawa, S. Goldberg, Edward S. Kim, Jill Walker, R. Raja, Feng Liu, Urban J. Scheuring, S. Peters   +19 more
semanticscholar   +1 more source

Investing Time for Your In-Game Boyfriends and BFFs: Time as Commodity and the Simulation of Emotional Labor in Mystic Messenger

Games Cult., 2018
Mystic Messenger is a real-time mobile dating simulator and otome game that simulates how people fall in love online. In this essay, I will look at significant parallels between casual games and otome games and point out the ways in which both define ...
S. Ganzon
semanticscholar   +1 more source

Dr. A.M.—A case of a modern mystic? Implications for psychology and medicine.

Spirituality in Clinical Practice, 2019
In this article we report some excerpts from the writings of Dr A.M., a healthy adult female, in relation to the knowledge she acquired during the regular mystical experiences she has been having since April 2014.
E. Facco, Daniela Lucangeli, Patrizio Emanuele Tressoldi   +2 more
semanticscholar   +1 more source

Mysticism and Mysticism

Blackfriars, 1957
Professor Zaehner’s new book is most timely, and—to anybody with any interest in the subject, from whatever point of view—quite absorbing. It is also a pioneer work, for although the study of ‘comparative mysticism’ is not totally new, the little that has hitherto been written about it has been mainly from an a priori standpoint with little regard for ...
openaire   +1 more source

Mystic: Mystifying IP Cores Using an Always-ON FSM Obfuscation Method

IEEE Computer Society Annual Symposium on VLSI, 2018
The separation of manufacturing and design processes in the integrated circuit industry to tackle the ever increasing circuit complexity and time to market issues has brought with it some major security challenges.
A. Patooghy, Ehsan Aerabi, H. Rezaei, Miguel Mark, M. Fazeli, Michel A. Kinsy   +5 more
semanticscholar   +1 more source

Mystics' Critiques of Mystical Experience

Revue de l'histoire des religions, 2004
Lorsque les mystiques critiquent l'expérience mystique Les études existantes sur le mysticisme ont souligné la place tenue par l' "expérience" dans l'écriture et la pratique mystiques. Cependant, l'examen de textes issus de traditions mystiques differentes montre que plusieurs auteurs mystiques étaient réservés sur la poursuite de cette ...
openaire   +2 more sources

Limochores mystic subsp. mystic

Limochores mystic mystic (Long Dash): Breeding resident. BRI, KEN, NEW, PRO, WAS. May 27- September 14.
openaire   +1 more source

Pascal’s mystic hexagram, and a conjectural restoration of his lost treatise on conic sections

, 2020
A. Centina
semanticscholar   +1 more source