Results 81 to 90 of about 122,056 (334)
Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy
Advanced Science, EarlyView.Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee +11 more
wiley +1 more source
The Optimal Uncertainty Algorithm in the Mystic Framework [PDF]
, 2012 We have recently proposed a rigorous framework for Uncertainty Quantification (UQ) in which UQ objectives and assumption/information set are brought into the forefront, providing a framework for the communication and comparison of UQ results.
McKerns, M. +4 more
core +1 more source
Advanced Science, EarlyView.Multi‐omic profiling of T1 high‐grade bladder cancer identifies a high‐risk subtype (T1HG1) driven by NQO1, which couples anoikis resistance with immune evasion. NQO1 orchestrates macrophage–T cell crosstalk suppression via CXCL9 modulation. Pharmacological NQO1 inhibition with skullcapflavone II enhances cisplatin efficacy, representing a promising ...
Bin Guo +20 more
wiley +1 more source
Jean-Paul Sartre: Mystical Atheist or Mystical Antipathist? [PDF]
, 2013 Jean-Paul Sartre is rarely discussed in the philosophy of religion. In 2009, however, Jerome Gellman broke the silence, publishing an article in which he argued that the source of Sartre’s atheism was neither philosophical nor existential, but mystical ...
Kirkpatrick, Kate
core
The challenge of the oceanic feeling: Romain Rolland’s mystical critique of psychoanalysis and his call for a ‘new science of the mind’ [PDF]
, 2017 In a letter written in 1927, the French writer Romain Rolland asked Sigmund Freud to analyse the “oceanic feeling,” a religious feeling of oneness with the entire universe.
Maharaj, Ayon
core +1 more source
Advanced Science, EarlyView.Accurate prediction of early recurrence in pancreatic ductal adenocarcinoma is vital for optimizing treatment. A novel, integrated radiomics‐pathology machine learning model successfully forecasts recurrence risks by analyzing preoperative CT images and computational pathology.
Sihang Cheng +17 more
wiley +1 more source
Shock and Vibration, 2004 Marine composite materials typically exhibit significant rate dependent response characteristics when subjected to extreme dynamic loading conditions.
James Lua +3 more
doaj +1 more source
Advanced Science, EarlyView.A semi‐interpenetrating engineered living material (sIHSELM), fabricated via thermosensitive hydroxybutyl chitosan and covalent protein self‐assembly, demonstrates exceptional mechanical properties and environmental stability. Shielding bacteria from harsh conditions, sIHSELM exhibits remarkable efficacy in ulcerative colitis treatment and pollutants ...
Zixian Bao +8 more
wiley +1 more source
A Revised Model for Muscarine Biosynthesis Involving Lysine Trimethylation
Angewandte Chemie, EarlyView.The fatal mushroom toxin l‐(+)‐muscarine is one of the most prominent natural products. We elucidated its biosynthetic origin in the sweating mushroom Collybia rivulosa based on incorporation of stable isotope‐labeled compounds and extensive mass spectrometric analyses.
Sebastian Dörner +4 more
wiley +2 more sources
Book Review: Mother of the Universe: Visions of the Goddess and Tantric Hymns of Enlightenment [PDF]
, 1995 A review of Lex Hixon\u27s Mother of the Universe: Visions of the Goddess and Tantric Hymns of ...
Dand, Arti
core +2 more sources