Results 101 to 110 of about 22,681 (186)

Neoadjuvant chemotherapy in soft tissue sarcomas: latest evidence and clinical implications

open access: yesTherapeutic Advances in Medical Oncology, 2017
Soft tissue sarcomas are a rare and multifaceted group of solid tumours. Neoadjuvant chemotherapy is increasingly used to limit loss of function after wide surgical excision with the ultimate aim of improving patient survival.
Sandro Pasquali, Alessandro Gronchi
doaj   +1 more source

Physical Mapping of Chromosome 12q Breakpoints in Lipoma, Pleomorphic Salivary Gland Adenoma, Uterine Leiomyoma, and Myxoid Liposarcoma

open access: yesGenomics, 1994
We report here the physical mapping of recurrent chromosome 12q13-q15 breakpoints in cell lines derived from primary myxoid liposarcoma, lipoma, uterine leiomyoma, and pleomorphic adenoma of the salivary glands. In fluorescence in situ hybridization (FISH) experiments, we first mapped the position of the chromosome 12 translocation breakpoint in ...
E F, Schoenmakers   +9 more
openaire   +2 more sources

Myxoid liposarcoma in a 91-year-old patient [PDF]

open access: yes, 2015
Background: Myxoid liposarcoma is a mesenchymal malignancy most commonly presenting in young adults. This tumor is known for its characteristic chromosomal rearrangement at the DDIT3 locus.
Sheffield, Brandon S., Nielsen, Torsten
core   +1 more source

Primary Orbital Pleomorphic Liposarcoma: An Aggressive Course

open access: yes, 2012
An aggressively poor course of primary orbital pleomorphic liposarcoma is presented. A 59-year-old man had suffered from multiple local recurrences and died 1 year after diagnosis of orbital pleomorphic liposarcoma.
Lee, Sang Yeul   +5 more
core   +1 more source

Efficacy of trabectedin in advanced soft tissue sarcoma: beyond lipo- and leiomyosarcoma

open access: yesDrug Design, Development and Therapy, 2015
Rita De Sanctis,1 Andrea Marrari,1 Silvia Marchetti,1 Chiara Mussi,2 Luca Balzarini,3 Fabio Romano Lutman,3 Primo Daolio,4 Stefano Bastoni,4 Alexia Francesca Bertuzzi,1,5 Vittorio Quagliuolo,2 Armando Santoro1 1Department of Medical Oncology and ...
De Sanctis R   +10 more
doaj  

FUS–DDIT3 Fusion Protein-Driven IGF-IR Signaling is a Therapeutic Target in Myxoid Liposarcoma

open access: yes, 2017
Purpose: Myxoid liposarcoma is an aggressive disease with particular propensity to develop hematogenic metastases. Over 90% of myxoid liposarcoma are characterized by a reciprocal t(12;16)(q13;p11) translocation.
Ilka Isfort   +16 more
core   +1 more source

Abstracts

open access: yesMolecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Trabectedin and Campthotecin Synergistically Eliminate Cancer Stem Cells in Cell-of-Origin Sarcoma Models

open access: yesNeoplasia: An International Journal for Oncology Research, 2017
Trabectedin has been approved for second-line treatment of soft tissue sarcomas. However, its efficacy to target sarcoma initiating cells has not been addressed yet.
Lucia Martinez-Cruzado   +8 more
doaj   +1 more source

Myxoid liposarcoma of the spermatic cord: A case report

open access: yes, 2007
Introduction: Myxoid liposarcoma is a rare condition and a very little number of cases have been described in the spermatic cord to date. It presents as painless scrotal or inguinal masses that are often confused with hydroceles or inguinal hernias ...
Vuruşkan, Hakan   +4 more
core  

The FUS-DDIT3 interactome in myxoid liposarcoma

open access: yes, 2019
Myxoid liposarcoma is a malignant fatty tumour that develops in the deep soft tissue. While local control rates are good, current chemotherapy options remain ineffective against metastatic disease.
Yu, Jamie Simin Emma
core   +1 more source

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