Results 21 to 30 of about 22,681 (186)

Molecular mechanisms underlying liposarcoma subtype transition and proteasome-associated targeted interventions [PDF]

Journal of Translational Medicine
Background Liposarcoma (LPS) is one of the most common soft tissue sarcomas and is characterized by marked heterogeneity and a strong tendency toward recurrence.
Jiahao Liu, Mingke Huo, Sihan Wu, Zhen Wang, Sanfei Peng, Yang Fu   +5 more
doaj   +2 more sources

B7-H3 membranous expression correlates with histological grading in a two-center cohort of 133 pre-treatment bone and soft tissue sarcoma samples [PDF]

BMC Cancer
Background B7-H3 targeted therapies are an upcoming promising treatment option for a variety of solid tumors. High levels of B7-H3 expression have only been reported for a few sarcoma subtypes in previous studies, but a systematic analysis in an ...
Linus D. Kloker, Robert Rottscholl, Jonas S. Heitmann, Peter Bronsert, David Braig, Katrin Benzler, Lars Zender, Christoph K. W. Deinzer   +7 more
doaj   +2 more sources

Atypical Spindle Cell/Pleomorphic Lipomatous Tumor with Atypical Imaging Features [PDF]

Diagnostics
A 54-year-old female patient presented with a gradually enlarging mass on the ulnar side of the left wrist. Magnetic resonance imaging demonstrated a fat-containing lesion deep within the flexor carpi ulnaris that showed heterogeneous signal intensity ...
Jiro Ichikawa, Tomonori Kawasaki, Kojiro Onohara, Masanori Wako, Rikito Tatsuno, Taro Fujimaki, Kouhei Mitsui, Tetsuhiro Hagino, Hirotaka Haro   +8 more
doaj   +2 more sources

Myxoid Pleomorphic Liposarcoma Imitating Recurrent Traumatic Hemopericardium. [PDF]

JACC Case Rep
Lo SW, Ikram J, Alqahtani M, Badwan O, Shaban M, Dermawan JKT, Klein AL.   +6 more
europepmc   +2 more sources

The Conundrum of Dedifferentiation in a Liposarcoma at a Peculiar Location: A Case Report and Literature Review

Medicina, 2023
Dedifferentiated liposarcoma of the deep soft tissue of the lower extremities is an infrequent finding. Myxoid liposarcoma is considered the most common soft tissue neoplasia arising in this anatomic region.
Ana-Maria Ciongariu, Adrian-Vasile Dumitru, Cătălin Cîrstoiu, Bogdan Crețu, Maria Sajin, Dana-Antonia Țăpoi, Aminia-Diana Ciobănoiu, Adrian Bejenariu, Andrei Marin, Mariana Costache   +9 more
doaj   +1 more source

Orbital liposarcoma: a retrospective, single-center study of thirteen patients [PDF]

International Journal of Ophthalmology, 2023
AIM: To explore the clinical and pathological characteristics of thirteen patients with orbital liposarcoma. METHODS: The clinical history data of thirteen patients diagnosed as orbital liposarcoma at Beijing Tongren Hospital, from 2006 to 2021 were ...
Ning Gao, Xin Ge, Cheng Pei, Jian-Min Ma, Ya-Guang Hu   +4 more
doaj   +1 more source

Comprehensive genomic profiling of a unique liposarcoma arising in a patient with Li–Fraumeni syndrome and the novel detection of c-myc amplification: a case report

Diagnostic Pathology, 2022
Background Germline TP53 mutations have been frequently reported in patients with Li–Fraumeni syndrome (LFS), resulting in a predisposition to various malignancies.
Hirofumi Watanabe, Fumiyoshi Fujishima, Toru Motoi, Yayoi Aoyama, Tetsuya Niihori, Masanobu Takahashi, Sho Umegaki, Hisashi Oishi, Hiroshi Tada, Ryo Ichinohasama, Hironobu Sasano   +10 more
doaj   +1 more source

Primary intrathoracic liposarcomas: A clinicopathologic and molecular study of 43 cases in one of the largest medical centers of China

Frontiers in Oncology, 2022
IntroductionPrimary intrathoracic liposarcoma is extremely rare, and most published series lack genetic analyses. The aim of our study is to better understand the clinicopathologic and genetic features of these rare lesions.Materials and methodsForty ...
You Xie, Wenyi Jing, Wei Zhao, Ran Peng, Min Chen, Ting Lan, Heng Peng, Xin He, Huijiao Chen, Zhang Zhang, Hongying Zhang   +10 more
doaj   +1 more source

Exploring Neutrophil Extracellular Traps in Canine Soft Tissue Sarcomas: A Preliminary Study With Translational Insights. [PDF]

Vet Med Sci
Neutrophil Extracellular Traps (NETs) in Canine Soft Tissue Sarcomas This study investigated the presence of neutrophil extracellular traps (NETs) in canine soft tissue sarcomas using dual immunohistochemistry for citrullinated histone‐3 and myeloperoxidase.
Yildirim B, Ipek V.
europepmc   +2 more sources

Well‐differentiated liposarcoma of tongue: A case report

Clinical Case Reports, 2023
Key Clinical Message It is important to consider WDLS as a potential cause of tongue lesions and include it in the list of differential diagnoses. When performing surgical intervention, it is crucial to remove enough tissue around the lesion, and regular
Moushami Singh, Arun R. Napit, Gunja Piya, Prabhat Chandra Thakur, Sambit Mohanty, Sayali Shinde, Ekta Jain, Hari Prasad Dhakal   +7 more
doaj   +1 more source