Results 51 to 60 of about 22,681 (186)

Axitinib has antiangiogenic and antitumorigenic activity in myxoid liposarcoma [PDF]

, 2016
Myxoid liposarcoma is a rare form of soft-tissue sarcoma. Although most patients initially respond well to treatment, approximately 21% relapse, highlighting the need for alternative treatments.
Kerr, Lauren T., Johns, Terrance G., Kerr, LT, Wilding, AL, Donoghue, JF, Wilding, Alexander L., Donoghue, Jacqueline F., Johns, TG   +7 more
core   +1 more source

Primary Splenic Pleomorphic Liposarcoma in a Bitch [PDF]

, 2021
Background: Liposarcoma is a malignant neoplasm of lipoblasts with low incidence in dogs, representing 1.7% of neoplasms diagnosed in the spleen. In veterinary medicine, this neoplasm is classified morphologically into the myxoid, well-differentiated ...
Nascente, Eduardo de Paula, Matos, Moema Pacheco Chediak, Santin, Ana Paula Iglesias, Moura, Veridiana Maria Brianezi Dignani de, Santos, Adriana da Silva, Porto, Regiani Nascimento Cagno, Adorno, Brunna Rocha   +6 more
core   +2 more sources

Routine MDM2 FISH Testing and Preoperative Biopsy Reduces Recurrence Rate of Atypical Lipomatous Tumours

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background Although MDM2 FISH test has been increasingly used to differentiate ALT and benign lipomatous tumours, its impact on clinical outcome remains underexplored. This study investigated whether routine MDM2 FISH testing on preoperative biopsy is associated with a reduction in the recurrence risk of ALT.
Samuel O. H. Ching, Anderson S. M. Leung, Raymond C. H. Yau, Albert Y. L. Lam, Tony W. H. Shek, Maximus C. F. Yeung   +5 more
wiley   +1 more source

Intraoperative Evaluation of Sarcoma Surgical Margins With Indocyanine Green Fluorescence Imaging: Results From an Observational Study

Journal of Surgical Oncology, EarlyView.
ABSTRACT Introduction Sarcomas are rare malignancies that affect both adults and children. Surgical removal with negative histopathological margins is the foundation of sarcoma treatment. Failure to achieve negative margins puts patients at risk of local recurrence (LR). LR rates range between 10% and 30%.
Sumail Bhogal, Matthew Gong, William Li, Brenda Diergaarde, Alma Heyl, Clark Roth, Lawrence Garvin II, Alexander Hoffman, Amanda Locker, Ines Lohse, Maria Silvaggio, Stella Lee, Richard McGough, Kurt Weiss   +13 more
wiley   +1 more source

Hsp90 inhibition by AUY922 as an effective treatment strategy against myxoid liposarcoma [PDF]

, 2015
Liposarcoma is one of the most common soft tissue sarcomas in adults. Recognized histological subtypes include well differentiated/dedifferentiated liposarcoma (WD/DDLS), myxoid liposarcoma (MLS) and pleomorphic liposarcoma.
Steinmann, S., Steinmann, Sara M., Agaimy, Abbas, Åman, Pierre, Haller, F., Schneider-Stock, R., Abou Merhi, R., Gali-Muhtasib, H., Schneider-Stock, Regine, Åman, Pierre,, Haller, Florian, Al-Halabi, R., Huebner, Kerstin, al-Halabi, Racha, Agaimy, A., Gali-Muhtasib, Hala Uthman, Abou-Merhi, Raghida, Huebner, K.   +17 more
core   +1 more source

Survival and prognostic factors among different types of liposarcomas based on SEER database

Scientific Reports
The aim of this study is to elucidate the disparities in survival and risk factors among different subtypes of liposarcoma, through analysis of epidemiological and prognostic data.
Jiaqi Zhao, WenLi Du, XiaoLiang Tao, AiAi Li, Yi Li, Shuai Zhang   +5 more
doaj   +1 more source

Pleomorphic Liposarcoma Arising in the Neck with Myxoid/Round Cell Features Showing DDIT3 Amplification [PDF]

American Journal of Clinical Pathology, 2015
Pleomorphic liposarcoma (PLPS) is the most rare type of LPS, accounting for fewer than 15% of LPSs. It usually presents in older adults and is most commonly located in the retroperitoneum or deep soft tissue of the extremities. PLPS is a high-grade sarcoma with 1/3 showing local recurrence and having overall 5-year survival rate …
Sara Mustafa, Delenya Allen, Adedoyin Kalejaiye, Edward Lee, Julie Fanburg-Smith, Farhan Khan, Tammey Naab   +6 more
openaire   +1 more source

Fat‐Containing Soft Tissue Lesions of the Limbs and Body Wall—A Pictorial Essay

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Lipomatous tumours are frequently encountered on imaging. The spectrum of lipomatous tumours ranges from simple lipomas, which can be monitored clinically, to high‐grade liposarcomas, which require timely, multidisciplinary management. The presence of fat within lesions may also be observed in non‐lipomatous tumours, as well as in a variety of
Kai‐Zheong Lim, Cathryn Hui
wiley   +1 more source

Evaluating Fine Needle Aspiration Cytology for Diagnostics of Soft Tissue and Bone Tumours

Cytopathology, EarlyView.
Systematic comparison of needle aspiration cytology and histopathology for 503 tumours in soft tissue and bone showed high concordance (positive predictive value 94%–100%, negative predictive value 83%–89%). In this original study, the authors show that FNAC is a safe and non‐invasive method for diagnosing suspected sarcomas, with the main objective to
Amanda Husu, Sandra Wessman, Karin Wallander, Felix Haglund de Flon   +3 more
wiley   +1 more source

Soft tissue sarcoma subtypes exhibit distinct patterns of acquired uniparental disomy

BMC Medical Genomics, 2012
Background Soft tissue sarcomas (STS) are heterogeneous mesenchymal tumors with diverse subtypes. STS can be classified into two main categories according to the type of genomic alteration: recurrent translocation driven STS, and non-recurrent ...
Tuna Musaffe, Ju Zhenlin, Amos Christopher I, Mills Gordon B   +3 more
doaj   +1 more source