Results 141 to 150 of about 583,924 (247)

A randomized, double-blind, placebo-controlled trial of olanzapine versus placebo plus ondansetron and dexamethasone for antiemetic prophylaxis in patients receiving oxaliplatin-, irinotecan-, or carboplatin-based chemotherapy. [PDF]

Support Care Cancer
Harikul W, Nimmannit A, Laocharoenkeat A, Phisalprapa P, Kositamongkol C, Thongkijpreecha P, Ithimakin S.   +6 more
europepmc   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

Clinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott, Sharon Nachman, Ethel D. Weld, Rachel Daley, Shakir Atoyebi, Robert Bies, Catriona Waitt, Adeniyi Olagunju   +7 more
wiley   +1 more source

A prokinetic agent DA-9701 formulated with Corydalis tuber and Pharbitidis semen improves nausea in migraine: A prospective observational study. [PDF]

Medicine (Baltimore)
Son H, Lee S, Lee MJ, Kim M.
europepmc   +1 more source

2016 MASCC and ESMO guideline update for the prevention of chemotherapy- and radiotherapy-induced nausea and vomiting and of nausea and vomiting in advanced cancer patients.

Annals of Oncology, 2016
F. Roila, A. Molassiotis, J. Herrstedt, M. Aapro, R. Gralla, E. Bruera, R. Clark-Snow, L. Dupuis, L. Einhorn, P. Feyer, P. Hesketh, K. Jordan, I. Olver, B. Rapoport, J. Roscoe, C. Ruhlmann, D. Walsh, D. Warr, M. D. Wetering   +18 more
semanticscholar   +1 more source

More Than a Question of Correlation: Characterization of the Evidentiary Basis for Biomarker Surrogates Used in European Marketing Authorizations

Clinical Pharmacology &Therapeutics, EarlyView.
Traditionally, clinical outcomes measuring how a patient feels, functions, or survives are preferred endpoints in clinical trials; however, some may take a long time to manifest in slowly developing diseases. Biomarkers, if properly validated, can serve as surrogate endpoints, acting as substitutes for clinical outcomes.
Renske Johanna Grupstra, Viktoriia Starokozhko, Elisabeth Bakker, Anna Maria Gerdina Pasmooij, Peter Gerardus Maria Mol   +4 more
wiley   +1 more source

Letter regarding "efficacy of esketamine in reducing nausea and vomiting after anesthesia: a systematic review and meta-analysis of randomized controlled trials". [PDF]

Ann Med
Mao M, Chen J.
europepmc   +1 more source

Cytologic Findings in Esophageal Perforation: An Institutional Experience With Pleural Fluid Specimens

Diagnostic Cytopathology, EarlyView.
ABSTRACT Introduction Esophageal perforation (EP) is a rare but life‐threatening condition, and most cases are due to iatrogenic causes. The rest occur spontaneously, due to malignancies, or trauma. The mortality rates can approach 50%, and delayed diagnosis of EP exacerbates patient outcomes.
Mason Marshall, Samer Khader, Sigfred Lajara, Liron Pantanowitz   +3 more
wiley   +1 more source

Efficacy of intravenous amisulpride and ondansetron in preventing post-operative nausea and vomiting in patients undergoing craniotomy for supratentorial tumour surgery: A randomised non-inferiority trial. [PDF]

Indian J Anaesth
Ravindranath S, Hrishi AP, Sethuraman M, Praveen CSR, Kesavapisharady K.   +4 more
europepmc   +1 more source

Aprepitant Has Mixed Effects on Nausea and Reduces Other Symptoms in Patients With Gastroparesis and Related Disorders.

Gastroenterology, 2018
P. Pasricha, Katherine P. Yates, I. Sarosiek, R. McCallum, T. Abell, K. Koch, L. Nguyen, W. Snape, W. Hasler, J. Clarke, S. Dhalla, E. Stein, Linda A. Lee, L. Miriel, M. V. Van Natta, M. Grover, G. Farrugia, J. Tonascia, F. Hamilton, H. Parkman   +19 more
semanticscholar   +1 more source

Understanding Engagement Experiences in an Adapted Digital Cognitive Behavioral Intervention for Lower‐Income Adults With Eating Disorders With Binge Eating and/or Purging: A Qualitative Analysis of Barriers and Facilitators

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This study explored the experiences of lower‐income adults in accessing and engaging with an adapted digital guided self‐help cognitive behavioral intervention for binge and/or purge‐type eating disorders. This study sought to inform future adaptation of evidence‐based eating disorder interventions to improve accessibility ...
Kimberly Yu, Siena Vendlinski, Hannah Beck, Nancy Jacquelyn Pérez‐Flores, Catherine R. Drury, Ellen E. Fitzsimmons‐Craft, Erin C. Accurso   +6 more
wiley   +1 more source