Aims Amoxicillin, a widely used β‐lactam antibiotic, requires improved pharmacokinetic characterization during breastfeeding. This study used a population pharmacokinetic (PopPK) approach to model amoxicillin concentrations in breast milk, identify variability sources and estimate infant exposure, applying worst‐case scenarios.
Sarah Baklouti +9 more
wiley +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Chiari I Malformation: Review and Update of Current Treatment Options
ABSTRACT The pathophysiology of Chiari malformation type I (CM‐I) is complex, involving structural abnormalities at the craniovertebral junction that result in herniation of the cerebellar tonsils through the foramen magnum. In this study, we aim to present and evaluate current treatment options for CM‐I, with a focus on evidence‐based clinical ...
Jordan J. Lo +11 more
wiley +1 more source
Background Nausea and vomiting during awake craniotomy (AC) can increase cerebral pressure and cause asphyxia and aspiration. 5-HT3 receptor antagonists, such as granisetron, are often administered before awakening to prevent nausea during AC.
Takehito Sato
doaj +1 more source
Comparación de dos estrategias lidocaina en comprimidos vs dulce por vía iral para tratar la odinofagía post extubación [PDF]
La incidencia de náusea y vómito postoperatorios (NVPO) en la población general se estima en un 20-30% pudiendo llegar hasta un 80% en grupos de alto riesgo. Se asocian a complicaciones e insatisfacción en el post operatorio.
Villalba Egas, Javier Adrián
core
Postoperative Nausea and Vomiting: Its Etiology, Treatment, and Prevention
M. Watcha, P. White
semanticscholar +1 more source
Voclosporin‐induced gingival enlargement: A case report
Abstract Background Drug‐influenced gingival enlargement (DIGE) is a recognized adverse effect of certain medications, particularly immunosuppressants like cyclosporin and tacrolimus. However, there have been no documented cases of DIGE associated with voclosporin, a newer calcineurin inhibitor used primarily to treat lupus nephritis.
Francesca Racca +2 more
wiley +1 more source
Prevalencia de afectos adversos de los implantes contraceptivos subdérmicos en adolescentes y adultas en el Hospital Gineco Obstétrico Isidro Ayora de Quito. 2012. [PDF]
Contexto: Los implantes contraceptivos subdérmicos proveen una alta efectividad contraceptiva reversible, contienen progestinas, son una excelente opción para mujeres que tienen contraindicaciones para los métodos combinados y para aquellas que desean ...
Alvear Loachamín, María Alejandra +1 more
core
Exploring the Anti‐Diabetic Potential of Anthocyanins: From Biochemical Pathways to Human Trials
ABSTRACT Diabetes mellitus (DM) is a global health challenge with increasing prevalence rates, particularly in low‐ and middle‐income countries. Anthocyanins (ACs) are potential bioactive compounds found in various fruits and vegetables, attracting the attention of researchers due to their possible role in managing diabetes and its complications ...
Lakshay Panchal +6 more
wiley +1 more source
Retrospective, Multicenter Study of Lacosamide to Treat Neonatal Seizures
ABSTRACT Objective Most antiseizure medications (ASMs) are prescribed off label for neonates. Lacosamide's efficacy in infants and availability in intravenous formulation suggest potential utility for neonates. We evaluated the safety and efficacy of lacosamide for neonatal seizures. Methods This 10‐center, retrospective study of neonates with seizures
Alexandra Santana Almansa +15 more
wiley +1 more source

