Results 231 to 240 of about 436,550 (248)

Efficacy and related factors of levonorgestrel‐releasing intrauterine system combined with metformin in fertility‐preserving treatment for atypical endometrial hyperplasia and early endometrial cancer: A retrospective cohort study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To compare the efficacy of the levonorgestrel‐releasing intrauterine system combined with metformin versus oral progestin combined with metformin in fertility‐preserving treatment for patients with atypical endometrial hyperplasia and early endometrial cancer, and to analyze related factors affecting efficacy.
Pengpeng Gu   +5 more
wiley   +1 more source

Napabucasin transforms liver microenvironment and boosts immunotherapy efficacy by converting potential metastases into “hot” tumors

open access: yesInterdisciplinary Medicine, EarlyView.
Napabucasin reduces liver metastases by reprogramming the hepatic microenvironment. It induces hepatocyte secretion of CCL21 via c‐Fos activation, recruiting lymphocytes and converting “cold” metastases into immunologically “hot” tumors. This effect is liver‐specific and independent of cancer cells.
Qiongqiong Wang   +19 more
wiley   +1 more source

Perfectionism and School Non‐Attendance Reasons in Adolescents: A Latent Profile Analysis

open access: yesJournal of Adolescence, EarlyView.
ABSTRACT Introduction Limited prior knowledge exists regarding perfectionism and other relevant educational variables, such as the wide spectrum of School Attendance Problems. However, perfectionism has been related to somatic complaints and symptoms, school burnout, and negative emotionality. Therefore, this study analyzes the association between this
Andrea Fuster   +3 more
wiley   +1 more source

TERAPÉUTICA: Nuevo método del tratamiento de la brucelosis [PDF]

open access: yes, 1951
Barber, Tracy E., Herrell, Wallace E.
core  

Predicting 7‐year‐olds mental health in the perinatal period: Development and internal validation of a multivariable model using the prospective ALSPAC cohort

open access: yesJCPP Advances, EarlyView.
Abstract Background Mental health difficulties in childhood are increasing. Prevention is the only sustainable and ethical public health approach. However, predicting which children are most at‐risk of mental health difficulties prior to symptoms emerging remains elusive.
Emma Butler   +3 more
wiley   +1 more source

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