Results 261 to 270 of about 585,553 (296)

Reshaping study design for faster extrapolation‐based drug approval in pediatric inflammatory bowel diseases: An ESPGHAN–NASPGHAN position paper

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Children with inflammatory bowel diseases (IBD) have limited access to the available advanced therapies, given the lengthy gap between adult and pediatric approval. We aimed to review key hurdles for pediatric trials and recommend practical solutions.
Dan Turner   +21 more
wiley   +1 more source

Health‐related quality of life in youth with chronic gastrointestinal disease following a biofeedback enhanced cognitive behavioral therapy intervention: A randomized controlled trial

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Pediatric patients with chronic gastrointestinal (GI) conditions including inflammatory bowel diseases (IBD) and irritable bowel syndrome (IBS) on average endorse lower health related quality of life (HRQOL) than their healthy counterparts.
S. Taylor Younginer   +6 more
wiley   +1 more source

Postoperative nausea and vomiting: translating pathophysiological mechanisms into clinical management. [PDF]

open access: yesPerioper Med (Lond)
Zhao X   +7 more
europepmc   +1 more source

Beyond eosinophils: A proteomic dissection of remodeling and inflammation in suspected eosinophilic esophagitis

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Eosinophilic esophagitis (EoE) is characterized by eosinophilic inflammation and epithelial remodeling. However, current biomarkers focus predominantly on eosinophilia, overlooking basal cell hyperplasia (BCH), a histologic feature that may persist despite treatment.
Adi Eindor‐Abarbanel   +7 more
wiley   +1 more source

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