Results 101 to 110 of about 9,401 (220)

Acute toxicity of ADB‐CHMINACA ‐ a case series of patients with pronounced central nervous symptoms including the posterior reversible encephalopathic syndrome

British Journal of Clinical Pharmacology, EarlyView.
Aim This report presents a series of 16 patients who were admitted to the emergency department following confirmed intake of the potent synthetic cannabinoid ADB‐CHMINACA. Methods The cases are drawn from a prospective observational study following the recreational use of synthetic cannabinoids.
Maren Hermanns‐Clausen, Michaela Sommer, Annette Zschiesche, Verena Angerer, Martin Scheu, Florian Eyer, Johannes Nadler, Volker Auwärter   +7 more
wiley   +1 more source

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum, Milli McMenamin, Tessa Khoo, John M. Edwin, Prathibha Jose, Liam A. O’Callaghan   +5 more
wiley   +1 more source

Náuseas e vómitos persistentes inexplicados: identificar o síndroma de hiperemese por canabinoides a propósito de um caso clínico

Revista Portuguesa de Medicina Geral e Familiar
Introdução: A canábis constitui a substância ilícita com maior prevalência de consumo ao longo da vida em Portugal. Apesar do seu uso medicinal pelas suas propriedades antieméticas tem sido reconhecida uma entidade clínica paradoxal – o síndroma de ...
Carolina Pinto-Gouveia, Joana Marques Pinto, Susana Renca   +2 more
doaj   +1 more source

Eficacia de los antieméticos para prevenir las náuseas y los vómitos en niños con tratamiento quimioterápico

, 2011
Conclusiones de los autores del estudio: los antieméticos, y sobre todo los del grupo antagonistas de los receptores 5-HT3, sirven para prevenir y tratar las náuseas y los vómitos asociados al tratamiento oncológico durante las primeras 24 horas.
Perdikidis Olivieri, Leo, Bonillo Perales, Antonio   +1 more
core  

Repeated intradermal lipopolysaccharide challenge responses in healthy volunteers: Implications for clinical pharmacology studies

British Journal of Clinical Pharmacology, EarlyView.
Aim Intradermal application of lipopolysaccharide (LPS), a Toll‐like receptor 4 agonist, induces a local inflammatory response and is used as a human challenge model to evaluate the pharmacodynamics of investigational medicinal products. While currently applied in a single, parallel‐group setting, alternative within‐subject designs involving repeated ...
Alexandra A. J. Sillé, Juliette A. van den Noort, Iva Lelios, Diana R. Pereira, Marzia A. Scelsi, Erica S. Klaassen, Philipp Schoenenberger, Naomi B. Klarenbeek, Pierre‐Eric Juif, Pascal Espie, Manon A. A. Jansen, Matthijs Moerland, Richard W. D. Welford   +12 more
wiley   +1 more source

Recuperando evidencias en pacientes oncohematológicos (3ª parte): valoración nutricional, nauseas y vómitos

NURE Investigación, 2009
Introducción: Se deben invertir esfuerzos en modificar los cuidados enfermeros basados en la experiencia por los basados en evidencias. Un primer paso es la difusión de los resultados de la investigación.
Natalia Lorenzo García (1), María Dolores Sánchez Ayala (1), Cristóbal Meseguer Liza (2), José María Estrada Lorenzo (3), Lourdes Zarate Riscal (4), Antonio Paredes Sidrach de Cardona (5), Eva Abad Corpa (6)   +6 more
doaj  

Precision medicine in paediatrics: Progress and priorities

British Journal of Clinical Pharmacology, EarlyView.
Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain, Claire Booth, Joseph F. Standing, Charlotte I. S. Barker   +3 more
wiley   +1 more source

Revisión bibliográfica de los abordajes no farmacológicos para las náuseas y los vómitos postquimioterapia. [PDF]

, 2017
UNO DE LOS TRATAMIENTOS QUE MÁS SE USAN CONTRA EL CÁNCER ES LA QUIMIOTERAPIA, TENIENDO COMO CONSECUENCIA UNA MULTITUD DE EFECTOS SECUNDARIOS. LAS PERSONAS QUE PADECEN CÁNCER, REFIEREN QUE LOS EFECTOS SECUNDARIOS QUE LES RESULTAN MÁS DESAGRADABLES SON LAS
Climent Toledo, Assumpta
core   +1 more source

Incidencia y factores de riesgo para náuseas y vómitos postoperatorios (NVPO) en pacientes adultos sometidos a colecistectomía bajo anestesia general balanceada en un hospital general [PDF]

, 2019
Determina la incidencia y factores de riesgo para la presentación de náuseas y vómitos posoperatorios durante las primeras 24 horas. Se encontró una alta incidencia de NVPO en los pacientes adultos sometidos a colecistectomía bajo anestesia general ...
Shiraishi Zapata, Carlos Javier
core  

Evaluating the (comparative) safety profile of the novel oral polio vaccine type 2 using individual case safety reports in VigiBase

British Journal of Clinical Pharmacology, EarlyView.
Aim Novel oral polio vaccine type 2 (nOPV2) was used under the WHO emergency use listing for circulating vaccine‐derived polio virus (cVDPV) outbreaks from 2021 to 2023. We assessed nOPV2 adverse events following immunization (AEFIs) and compared its safety profile to other vaccines using VigiBase.
Comfort Kunak Ogar, Malede Mequanent Sisay, Leonardo Roque‐Pereira, Christine Leopold, Patrick C. Souverein, Aukje K. Mantel‐Teeuwisse, Marie L. De Bruin   +6 more
wiley   +1 more source