Results 71 to 80 of about 2,640 (193)

Clinical Outcomes and Patient Experiences With Celiprolol Therapy in Vascular Ehlers–Danlos Syndrome: The First Non‐European Cohort

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Vascular Ehlers–Danlos syndrome (vEDS) is a hereditary connective tissue disorder caused by heterozygous pathogenic variants in COL3A1. European studies have shown that celiprolol may reduce the risk of life‐threatening vascular events, but outcomes in non‐European populations and the therapy's psychological impact remain unclear. We conducted
Megumi Furuhata‐Yoshimura, Tomomi Yamaguchi, Tomoki Kosho   +2 more
wiley   +1 more source

Utilização de antieméticos no tratamento antineoplásico de pacientes oncológicos

Revista Brasileira de Farmácia Hospitalar e Serviços de Saúde, 2019
Os medicamentos antineoplásicos exercem sua função contra o câncer trazendo inúmeros efeitos colaterais ao paciente. Para os esquemas de tratamento usualmente empregados, os efeitos colaterais mais freqüentes são náuseas e vômitos.
JULIANA BECKER, JEANINE MARIE NARDIN
doaj  

Histidine Supplementation Stabilizes Hearing and Vision and Improves Growth in HARS1‐Related Autosomal Recessive Disorder Associated With Usher‐Like Symptoms

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal recessive HARS1‐related disorder (originally described as Usher syndrome type 3B) caused by a homozygous Y454S variant in the histidyl‐tRNA synthetase gene (HARS1) is characterized by progressive sensorineural hearing and vision loss and respiratory deterioration with risk for sudden death following febrile illnesses.
Victoria Mok Siu, Rosan Kenana, Rana Chakrabarti, Sarah D. P. Wilhelm, Joseph Andrews, Susan J. Leat, Christina Parker, Michael Miller, Leslie A. Nangle, Wendy McCaul, Ashfia Chowdhury, Natalie Hutchings, Ryan A. Adams, Lauren Guy, Mandy Rhody, Verena Juncal, Marisa I. Mendes, Desiree E. C. Smith, Gajja S. Salomons, Angelica A. Moresco, Daphne L. McCulloch, D. Holmes Morton, Ilka U. Heinemann, C. Anthony Rupar   +23 more
wiley   +1 more source

Sappanwood extract modulates hepatic structure–function in hepatomegaly and hepcidin related iron regulatory pathways in a phenylhydrazine induced hemolytic anemia rat model relevant to thalassemia

Animal Models and Experimental Medicine, EarlyView.
Phenylhydrazine (PHZ) induces hemolytic anemia characterized by increased erythrocyte destruction and ineffective erythropoiesis, leading to hepcidin suppression through disruption of the BMP/SMAD signaling pathway. Reduced hepcidin levels enhance intestinal iron absorption and hepatic iron accumulation, leading to hepatic iron overload.
Mohammad Indra Pratama, Ratu Safitri, Desak Made Malini, Mas Rizky A. A. Syamsunarno, Mohammad Ghozali, Madihah Madihah   +5 more
wiley   +1 more source

Náuseas, vômitos e qualidade de vida de mulheres com câncer de mama em tratamento quimioterápico

Revista Gaúcha de Enfermagem
Objetivou-se avaliar a qualidade de vida (QV) de mulheres com câncer de mama em tratamento quimioterápico e identificar a ocorrência de náuseas e vômitos durante o tratamento.
Thais de Oliveira Gozzo, Aline Maria Bonini Moysés, Pamina Roberta da Silva, Ana Maria de Almeida   +3 more
doaj   +3 more sources

Two Years of Ocrelizumab Treatment in Black and Hispanic People with Multiple Sclerosis in CHIMES: A Single‐Arm Clinical Trial

Annals of Neurology, EarlyView.
Objective To evaluate the effectiveness and safety of ocrelizumab in self‐identified black and Hispanic people with relapsing multiple sclerosis. Methods The Characterization of Ocrelizumab in Minorities with Multiple Sclerosis (CHIMES) trial, a prospective, open‐label, single‐arm, phase 4 study, intentionally recruited underrepresented populations in ...
Lilyana Amezcua, Anthony T. Reder, Evanthia Bernitsas, Nancy L. Monson, Timothy Vartanian, Gregory F. Wu, Mansoor Saleh, Annette Okai, Ahmed Z. Obeidat, Dilraj Sokhi, Rikisha Parekh, Jinglan Pei, Christopher Harp, David Clayton, Ibraheem Abioye, Mitzi J. Williams, for the CHIMES Study Group   +16 more
wiley   +1 more source

Editorial Commentary: Estrogen Influences Shoulder Health

Arthroscopy, EarlyView.
Abstract Estrogen influences bone mineral density, muscle quality and quantity, and collagen synthesis, rotator cuff tearing, worse outcomes after rotator cuff repair, hyperlaxity, and adhesive capsulitis. In this commentary, we discuss the potential explanations for the highly significant associations between hormonal systemic birth control and a ...
Peter Chalmers, Robert Tashjian
wiley   +1 more source

Náuseas e vómitos persistentes inexplicados: identificar o síndroma de hiperemese por canabinoides a propósito de um caso clínico

Revista Portuguesa de Medicina Geral e Familiar
Introdução: A canábis constitui a substância ilícita com maior prevalência de consumo ao longo da vida em Portugal. Apesar do seu uso medicinal pelas suas propriedades antieméticas tem sido reconhecida uma entidade clínica paradoxal – o síndroma de ...
Carolina Pinto-Gouveia, Joana Marques Pinto, Susana Renca   +2 more
doaj   +1 more source

Intra‐articular Orthobiologics Show Statistically but Not Clinically Meaningful Improvements Compared With Viscosupplementation in Knee Osteoarthritis: A Network Meta‐analysis of Randomized Controlled Trials

Arthroscopy, EarlyView.
Purpose To evaluate the comparative effectiveness of intra‐articular platelet‐rich plasma (PRP), stromal vascular fraction (SVF), bone marrow aspirate concentrate (BMAC), umbilical cord‐derived mesenchymal stem cell (UC‐MSC), and hyaluronic acid (HA) for pain relief and functional improvement in patients with knee osteoarthritis through network meta ...
Joo Hyung Han, Min Jung, Kwangho Chung, Hyun‐Soo Moon, Se‐Han Jung, Sung‐Hwan Kim   +5 more
wiley   +1 more source

Recuperando evidencias en pacientes oncohematológicos (3ª parte): valoración nutricional, nauseas y vómitos

NURE Investigación, 2009
Introducción: Se deben invertir esfuerzos en modificar los cuidados enfermeros basados en la experiencia por los basados en evidencias. Un primer paso es la difusión de los resultados de la investigación.
Natalia Lorenzo García (1), María Dolores Sánchez Ayala (1), Cristóbal Meseguer Liza (2), José María Estrada Lorenzo (3), Lourdes Zarate Riscal (4), Antonio Paredes Sidrach de Cardona (5), Eva Abad Corpa (6)   +6 more
doaj