Results 91 to 100 of about 11,699 (159)

ATF4, ZIK1, and PNMA3 Transcriptomic Signatures Predict Chemoradiotherapy Response in Cervical Cancer

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Background Cervical cancer (CC) is a main malignancy affecting women globally, with a high mortality rate. Chemoradiotherapy resistance is a significant factor in determining treatment outcomes, and prognostic biomarkers are essential for the appropriate selection of therapeutic strategies.
Angelo Borges de Melo Neto, Fábio Ribeiro Queiroz, Carolina Pereira de Souza Melo, Bruna Custódio Dias Duarte, Jorge Gomes Goulart Ferreira, Izabela Ferreira Gontijo de Amorim, Laurence Rodrigues do Amaral, Pedro Luiz Lima Bertarini, Telma Maria Rossi de Figueiredo Franco, Andréa Teixeira de Carvalho, Olindo Assis Martins‐Filho, Wander de Jesus Jeremias, Letícia da Conceição Braga, Paulo Guilherme de Oliveira Salles, Matheus de Souza Gomes   +14 more
wiley   +1 more source

The evolving landscape of the Warburg effect in gastric cancer: From molecular mechanisms to targeted therapy

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
Hypoxia, oncogenic signaling, transcriptional and epigenetic remodeling, and H. pylori–microbiota interactions drive the Warburg effect in gastric cancer. Enhanced glycolysis and lactate export support biosynthesis, remodel the tumor microenvironment, promote stromal activation and immune suppression, and reveal actionable biomarkers and therapeutic ...
Guanmo Liu, Pan Li, Zizhuo Li, Jie Li, Chenggang Zhang, Yihua Wang, Weiming Kang, Xin Ye   +7 more
wiley   +1 more source

Postbiotics in Food Systems: Components, Production Methods, Food Applications, Functional Properties, and Technological Challenges

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
This review provides a comprehensive, engineering‐oriented synthesis of postbiotics as next‐generation functional food ingredients. It first outlines the principal production routes for postbiotic generation, encompassing thermal technologies, non‐thermal technologies, and extraction/purification methods, and subsequently examines the analytical and ...
Tansu Taspinar, Nuray Güzeler
wiley   +1 more source

Vitex oreadica and V. umbellata (Lamiaceae): two new species from Cerrado and Atlantic forest of Brazil

Nordic Journal of Botany, Volume 2026, Issue 8, August 2026.
Vitex L. is a pantropical genus of Lamiaceae comprising 209 taxa. Brazil harbors 35 species, representing nearly 50% of the genus richness in the Neotropics, with the Amazon showing the highest richness, followed by the Atlantic Forest and Cerrado domains. Nevertheless, most taxonomic studies of the genus have been conducted in Africa and Asia.
Thaís Teixeira Conegiro, Guilherme Medeiros Antar, Carla Poleselli Bruniera   +2 more
wiley   +1 more source

Differential Impact of Pharmacokinetic and Pharmacodynamic Variability on Response to Combination Therapy

Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
ABSTRACT Interindividual variability (IIV) in drug response complicates both fixed‐dose design and individualized therapy. Understanding how pharmacokinetic (PK) and pharmacodynamic (PD) processes jointly shape this variability is essential, particularly in combination therapy, where multiple interacting pathways influence outcomes. This study employed
Kuteesa R. Bisaso, Ronald Kadada Karyaburo, Jackson K. Mukonzo, Ene I. Ette   +3 more
wiley   +1 more source

The ELAVL1‐PLAUR‐suPAR Axis Exacerbates Diabetic Nephropathy by Promoting Podocyte Injury and Inflammation

Journal of Diabetes, Volume 18, Issue 8, August 2026.
This study identifies a novel pathogenic pathway in DN wherein hyperglycemia‐induced ELAVL1 upregulates PLAUR expression and promotes suPAR release from podocytes, leading to renal inflammation and injury. ABSTRACT Background Diabetic nephropathy (DN) is a leading cause of end‐stage renal disease.
DanDan Xu, Liang Xu, LinLin Li
wiley   +1 more source

Parasitoidism by Brachymeria pandora (Hymenoptera: Chalcididae) in Pupae of Danaus erippus (Lepidoptera: Nymphalidae) in an Urban Savanna Area

Austral Entomology, Volume 65, Issue 3, August 2026.
ABSTRACT The Chalcididae comprises parasitoid wasps that attack various invertebrate groups. Within the family, some Brachymeria species specialises in infecting pupae of Lepidoptera. Here, we quantitatively describe the relationship between Brachymeria pandora and the Southern Monarch butterfly, Danaus erippus, in urban areas of Cuiabá, Mato Grosso ...
Wenrique Verza, Alan Eriksson
wiley   +1 more source

O início da escolarização primária no final do século xix em dois núcleos coloniais italianos

Revista de Educação PUC-Campinas, 2009
Este artigo aborda a maneira como ocorreu o processo de escolarização primária nas colônias italianas de Alfredo Chaves no Paraná e de São Caetano em São Paulo no final do século XIX e início do século XX; analisa as iniciativas de abertura das ...
Eliane Mimesse, Elaine Cátia Falcade Maschio   +1 more
doaj  

Temporal Association Between COVID‐19 Vaccination and HBsAg Loss in Chronic Hepatitis B Infection: An Interrupted Time Series Analysis

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 4, Page 517-526, August 2026.
In 59,946 chronic hepatitis B patients followed over 23 years, COVID‐19 vaccination rollout was temporally associated with a 56% increase in HBsAg loss rates (peak 1.27 per 100 person‐years in 2022), followed by gradual waning. Negative control outcomes showed no similar pattern, supporting biological specificity. ABSTRACT Background and Aims Hepatitis
Jonggi Choi, Allison Carroll, Vy H. Nguyen, Megan Michta, Xuan Q. Zhang, Young‐Suk Lim, Raymond T. Chung   +6 more
wiley   +1 more source

Núcleos diretos e indiretos: técnica de confecção

Revista Pró-UniverSUS, 2017
A restauração de dentes tratados endodonticamente ainda representa um desafio à odontologia moderna. Estes dentes normalmente apresentam-se mais frágeis e desidratados, necessitando de um núcleo intra-radicular como um retentor para uma prótese fixa ...
Gabriella Francisco Manta, Nadine Vibian Taira, Vivian Ribeiro da Silva Santos, Paula Aparecida Monfardini Gonçalves, Taciana Barcellos Carvalheira, Frederico dos Reis Goyatá   +5 more
doaj