Results 71 to 80 of about 14,756 (211)
Exploratory 7-Tesla magnetic resonance spectroscopy in Huntington’s disease provides in vivo evidence for impaired energy metabolism [PDF]
, 2011 Neurological Motor ...
Simon J. A. den Bogaard +6 more
core +1 more source
Magnetic Resonance in Medicine, EarlyView.ABSTRACT Purpose This study investigates the effect of VAPOR water suppression and metabolite cycling on metabolite quantification and macromolecules in proton magnetic resonance spectroscopy. Methods Single‐voxel semi‐LASER spectra (TR/TE = 3000/28 ms) and metabolite‐nulled spectra (macromolecules) were acquired in five healthy subjects in the ...
Dinesh K. Deelchand +1 more
wiley +1 more source
Magnetic Resonance Spectroscopy in Neurofibromatosis
Pediatric Neurology Briefs, 1999 The functional significance of T2 hyperintense lesions (UBOs) and their role in learning disabilities associated with neurofibromatosis type 1 (NF-1) were studied by quantitative magnetic resonance spectroscopy (MRS) in 7 male patients, aged 6-19 years ...
J Gordon Millichap
doaj +1 more source
GABA deficiency in NF1: a multimodal [11C]-Flumazenil and spectroscopy study [PDF]
, 2016 Objective: To provide a comprehensive investigation of the GABA system in patients with Neurofibromatosis type 1 (NF1) that allows understanding the nature of the GABA imbalance in humans at pre- and post-synaptic levels. Methods: In this cross-sectional
Abrunhosa, AJ +6 more
core +1 more source
Magnetic Resonance in Medicine, EarlyView.ABSTRACT Purpose Quantification of metabolite concentrations using MRS requires tissue‐dependent signal corrections. Accurate estimation of voxel tissue composition is therefore essential. Commonly used brain tissue segmentation tools differ in their algorithms and implementation, potentially introducing variability in MRS‐derived concentration ...
Jessica Archibald +12 more
wiley +1 more source
Вавиловский журнал генетики и селекции, 2015 Proportions of major neurometabolites with regard to their total amount in the dorsal region of the hippocampus were studied in adult male rats of populations selected for long for increase and absence of aggressivefearful response to humans and in ...
R. G. Gulevich +4 more
doaj +1 more source
Behavioral impairment in SHATI/NAT8L knockout mice via dysfunction of myelination development [PDF]
, 2017 We have identified SHATI/NAT8L in the brain of mice treated with methamphetamine. Recently, it has been reported that SHATI is N-acetyltransferase 8-like protein (NAT8L) that produces N-acetylaspatate (NAA) from aspartate and acetyl-CoA.
Furukawa-Hibi Yoko +8 more
core +3 more sources
GABA+‐Edited Magnetic Resonance Spectroscopy Deep Learning Quality Assessment Framework
Magnetic Resonance in Medicine, EarlyView.ABSTRACT Purpose Motivated by the need to improve GABA+‐edited magnetic resonance spectroscopy (MRS) quality, we developed a three‐module framework to improve transient averaging based on quality. We hypothesized that training a deep learning (DL) model to differentiate spectrum quality could improve transient averaging compared to traditional ...
Hanna Bugler +2 more
wiley +1 more source
Use of localized proton nuclear magnetic resonance spectroscopy in Canavan's disease
The Turkish Journal of Pediatrics, 1998 Canavan's disease is characterized by megalencephaly, leukodystrophy and early motor and mental retardation. On computerized tomography and magnetic resonance imaging, severe changes compatible with white matter disease due to demyelination is ...
N Aydinli, M Calişkan, M Calay, M Ozmen
doaj
Using NMR-based metabolomics to evaluate postprandial urinary responses following consumption of minimally processed wheat bran or wheat aleurone by men and women [PDF]
, 2016 Wheat bran, and especially wheat aleurone fraction, are concentrated sources of a wide range of components which may contribute to the health benefits associated with higher consumption of whole-grain foods. This study used NMR metabolomics to evaluate
Brennan, Lorraine +9 more
core +4 more sources