Results 81 to 90 of about 14,756 (211)

Associations of cannabis use, tobacco use and co‐use with brain volume: A systematic review and meta‐analysis

Addiction, EarlyView.
Abstract Background and aims Cannabis is the most widely used illicit drug worldwide and is often co‐used with tobacco, the leading cause of preventable death. Although cannabis and tobacco have distinct neurobiological actions, their associations with brain volumes are unclear.
Katherine Sawyer, Tom P. Freeman, Martine Skumlien, Esther Walton, Thomas Lancaster, Jorien L. Treur, Valentina Lorenzetti, Anna K. M. Blackwell, Chloe Burke, Richie J. Carr, Constantinos Constantinides, Maisie Cox, Sarah Dance, Shadi Daryan, Sorcha Hamilton, Tom Jenkins, Gemma M. J. Taylor   +16 more
wiley   +1 more source

Deciphering Cold Stress Resilience: Multiomics Insights in Contrasting Wheat Genotypes From the Western Himalayas

Plant Biotechnology Journal, EarlyView.
ABSTRACT Cold stress threatens wheat productivity, particularly in regions with extreme climatic conditions. To elucidate the molecular mechanisms underlying wheat's response to cold stress, we performed a multiomics analysis integrating lipidomics, transcriptomics, proteomics and metabolomics.
Sofora Jan, Farkhandah Jan, Mukesh Rathore, Yogita Singh, Prexha Kapoor, Palak Chaturvedi, Arindam Ghatak, Palakurthi Ramesh, Upendra Kumar, Manoj Prasad, Sundeep Kumar, Sachin Rustgi, Wolfram Weckwerth, Sanjay Kalia, Rajeev Kumar Varshney, Reyazul Rouf Mir   +15 more
wiley   +1 more source

Rett Syndrome [PDF]

, 2009
Rett syndrome is a thief! It robs little girls of their projected life. It lulls their families into a false sense of security while their little girls develop normally for 6 to 18 months.
Cox, Deborah Ann
core  

Multimodal MRI as a diagnostic biomarker for amyotrophic lateral sclerosis [PDF]

, 2014
Objective Reliable biomarkers for amyotrophic lateral sclerosis ( ALS ) are needed, given the clinical heterogeneity of the disease. Here, we provide proof‐of‐concept for using multimodal magnetic resonance imaging ( MRI ) as a diagnostic biomarker for
Barker, Peter B., Callaghan, Brian C., Carlos, Ruth C., Dwamena, Ben A., Edden, Richard A. E., Feldman, Eva L., Foerster, Bradley R., Mohamed, Mona A., Petrou, Myria, Pomper, Martin G., Welsh, Robert C.   +10 more
core   +1 more source

Spectral Representation of Neurochemicals With Phase, Frequency Offset, and Lineshape Invariance: Application to JPRESS for In Vivo Concentration and T2 Mapping by Deep Learning

Magnetic Resonance in Medicine, Volume 95, Issue 6, Page 3052-3064, June 2026.
ABSTRACT Purpose Using artificial intelligence neural networks to generate a representation that maps the input directly to neurochemical concentrations and metabolite‐level average transverse relaxation times (T2). Methods The proposed model used time‐domain JPRESS data as input and was trained to be invariant to phase shifts, frequency offsets, and ...
Yan Zhang, Jun Shen
wiley   +1 more source

Detection of Metabolites by Proton Ex Vivo NMR, in Vivo MR Spectroscopy Peaks and Tissue Content Analysis: Biochemical-Magnetic Resonance Correlation: Preliminary Results [PDF]

, 2009
*Aim*: Metabolite concentrations by in vivo magnetic resonance spectroscopy and ex vivo NMR spectroscopy were compared with excised normal human tissue relaxation times and tissue homogenate contents. *Hypothesis*: Biochemical analysis
Arun Agrawala, Madan Rehani, Rakesh Sharma   +2 more
core   +1 more source

Radiation Effects on Normal Brain in Subjects With Recurrent Glioblastoma by Spectroscopic MRI

NMR in Biomedicine, Volume 39, Issue 6, June 2026.
Whole‐brain spectroscopic MRI in recurrent glioblastoma revealed modest, dose‐dependent metabolic changes in previously irradiated normal‐appearing brain. N‐acetylaspartate declined with increasing prior radiation dose, while choline changed minimally, producing a baseline rise in Cho:NAA. These findings support patient‐specific dose‐correction maps to
Abram Abdou, Sulaiman Sheriff, Kelly Rojas, Miah Nicholls, Eric A. Mellon   +4 more
wiley   +1 more source

Characterizing Fatigue-Related White Matter Changes in MS: A Proton Magnetic Resonance Spectroscopy Study

Brain Sciences, 2019
Few cross-sectional studies have investigated the correlation between neurochemical changes and multiple sclerosis (MS) fatigue, but little is known on the fatigue-related white matter differences between time points.
Kalyan Yarraguntla, Fen Bao, Samuel Lichtman-Mikol, Sara Razmjou, Carla Santiago-Martinez, Navid Seraji-Bozorgzad, Shitiz Sriwastava, Evanthia Bernitsas   +7 more
doaj   +1 more source

Serial Whole-Brain N-Acetylaspartate Concentration in Healthy Young Adults [PDF]

American Journal of Neuroradiology, 2007
Although the concentration of N-acetylaspartate (NAA) is often used as a neuronal integrity marker, its normal temporal variations are not well documented. To assess them over the 1-2 year periods of typical clinical trials, the whole-brain NAA concentration was measured longitudinally, over 4 years, in a cohort of healthy young adults.
Rigotti, D. J., INGLESE, MARIA MATILDE, Babb, J. S., Rovaris, M., Benedetti, B., Filippi, M., Grossman, R. I., Gonen, Oded   +7 more
openaire   +3 more sources

Asymptomatic Versus Symptomatic Alzheimer's Disease Neuropathology: A Systematic Review of Differences Reported in Post‐Mortem Studies

Neuropathology and Applied Neurobiology, Volume 52, Issue 3, June 2026.
Graphical summary of post‐mortem brain tissue findings that differ between symptomatic and asymptomatic AD. Current evidence suggests reduced accumulation of Aβ and p‐tau oligomers, particularly at synapses, preserved neuronal and synaptic integrity and metabolic activity and a dynamic profile of glial and immune responses in ASYMAD.
Thiago Guilherme Rêgo Barros, Laura Barbosa Grossi, Maria Letícia da Silva Campos, Israel Bem‐Hur Netto Cardoso, Antônio Lúcio Teixeira, Aline Silva de Miranda, Eliana Cristina de Brito Toscano   +6 more
wiley   +1 more source